-
公开(公告)号:US20070066810A1
公开(公告)日:2007-03-22
申请号:US11550911
申请日:2006-10-19
申请人: Lowell Brady , Kevin Klucher , Chung Chan , Dennis Dong , Hong Liu , Paul Sheppard , Thomas Bukowski
发明人: Lowell Brady , Kevin Klucher , Chung Chan , Dennis Dong , Hong Liu , Paul Sheppard , Thomas Bukowski
IPC分类号: C07K16/24
CPC分类号: A61K38/20 , A61K38/00 , C07K14/54 , C07K14/555 , C07K2319/00 , Y10S435/81 , Y10S435/975 , Y10S514/894
摘要: Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor or exhibit biological activity. One type of biological activity that is shown is an antiviral activity.
-
公开(公告)号:US20070055054A1
公开(公告)日:2007-03-08
申请号:US11550904
申请日:2006-10-19
申请人: Lowell Brady , Kevin Klucher , Chung Chan , Dennis Dong , Hong Liu , Paul Sheppard , Thomas Bukowski
发明人: Lowell Brady , Kevin Klucher , Chung Chan , Dennis Dong , Hong Liu , Paul Sheppard , Thomas Bukowski
IPC分类号: C07K16/24
CPC分类号: A61K38/20 , A61K38/00 , C07K14/54 , C07K14/555 , C07K2319/00 , Y10S435/81 , Y10S435/975 , Y10S514/894
摘要: Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor or exhibit biological activity. One type of biological activity that is shown is an antiviral activity.
-
公开(公告)号:US20070054376A1
公开(公告)日:2007-03-08
申请号:US11550613
申请日:2006-10-18
申请人: Lowell Brady , Kevin Klucher , Chung Chan , Dennis Dong , Hong Liu , Paul Sheppard , Thomas Bukowski
发明人: Lowell Brady , Kevin Klucher , Chung Chan , Dennis Dong , Hong Liu , Paul Sheppard , Thomas Bukowski
CPC分类号: A61K38/20 , A61K38/00 , C07K14/54 , C07K14/555 , C07K2319/00 , Y10S435/81 , Y10S435/975 , Y10S514/894
摘要: Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor or exhibit biological activity. One type of biological activity that is shown is an antiviral activity.
-
公开(公告)号:US20070048276A1
公开(公告)日:2007-03-01
申请号:US11549729
申请日:2006-10-16
申请人: Lowell Brady , Kevin Klucher , Chung Chan , Dennis Dong , Hong Liu , Paul Sheppard , Thomas Bukowski
发明人: Lowell Brady , Kevin Klucher , Chung Chan , Dennis Dong , Hong Liu , Paul Sheppard , Thomas Bukowski
CPC分类号: A61K38/20 , A61K38/00 , C07K14/54 , C07K14/555 , C07K2319/00 , Y10S435/81 , Y10S435/975 , Y10S514/894
摘要: Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor or exhibit biological activity. One type of biological activity that is shown is an antiviral activity.
-
公开(公告)号:US20070048275A1
公开(公告)日:2007-03-01
申请号:US11549707
申请日:2006-10-16
申请人: Lowell Brady , Kevin Klucher , Chung Chan , Dennis Dong , Hong Liu , Paul Sheppard , Thomas Bukowski
发明人: Lowell Brady , Kevin Klucher , Chung Chan , Dennis Dong , Hong Liu , Paul Sheppard , Thomas Bukowski
CPC分类号: A61K38/20 , A61K38/00 , C07K14/54 , C07K14/555 , C07K2319/00 , Y10S435/81 , Y10S435/975 , Y10S514/894
摘要: Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor or exhibit biological activity. One type of biological activity that is shown is an antiviral activity.
-
公开(公告)号:US20070041975A1
公开(公告)日:2007-02-22
申请号:US11550899
申请日:2006-10-19
申请人: Lowell Brady , Kevin Klucher , Chung Chan , Dennis Dong , Hong Liu , Paul Sheppard , Thomas Bukowski
发明人: Lowell Brady , Kevin Klucher , Chung Chan , Dennis Dong , Hong Liu , Paul Sheppard , Thomas Bukowski
IPC分类号: A61K39/395 , C07K16/24
CPC分类号: A61K38/20 , A61K38/00 , C07K14/54 , C07K14/555 , C07K2319/00 , Y10S435/81 , Y10S435/975 , Y10S514/894
摘要: Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor or exhibit biological activity. One type of biological activity that is shown is an antiviral activity.
-
公开(公告)号:US20070073044A1
公开(公告)日:2007-03-29
申请号:US11550903
申请日:2006-10-19
申请人: Lowell Brady , Kevin Klucher , Chung Chan , Dennis Dong , Hong Liu , Paul Sheppard , Thomas Bukowski
发明人: Lowell Brady , Kevin Klucher , Chung Chan , Dennis Dong , Hong Liu , Paul Sheppard , Thomas Bukowski
IPC分类号: C07K16/24
CPC分类号: A61K38/20 , A61K38/00 , C07K14/54 , C07K14/555 , C07K2319/00 , Y10S435/81 , Y10S435/975 , Y10S514/894
摘要: Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor or exhibit biological activity. One type of biological activity that is shown is an antiviral activity.
-
公开(公告)号:US20070059313A1
公开(公告)日:2007-03-15
申请号:US11550909
申请日:2006-10-19
申请人: Lowell Brady , Kevin Klucher , Chung Chan , Dennis Dong , Hong Liu , Paul Sheppard , Thomas Bukowski
发明人: Lowell Brady , Kevin Klucher , Chung Chan , Dennis Dong , Hong Liu , Paul Sheppard , Thomas Bukowski
IPC分类号: A61K39/395 , C07K16/24
CPC分类号: A61K38/20 , A61K38/00 , C07K14/54 , C07K14/555 , C07K2319/00 , Y10S435/81 , Y10S435/975 , Y10S514/894
摘要: Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor or exhibit biological activity. One type of biological activity that is shown is an antiviral activity.
-
公开(公告)号:US20070055053A1
公开(公告)日:2007-03-08
申请号:US11550879
申请日:2006-10-19
申请人: Lowell Brady , Kevin Klucher , Chung Chan , Dennis Dong , Hong Liu , Paul Sheppard , Thomas Bukowski
发明人: Lowell Brady , Kevin Klucher , Chung Chan , Dennis Dong , Hong Liu , Paul Sheppard , Thomas Bukowski
IPC分类号: C07K16/24
CPC分类号: A61K38/20 , A61K38/00 , C07K14/54 , C07K14/555 , C07K2319/00 , Y10S435/81 , Y10S435/975 , Y10S514/894
摘要: Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor or exhibit biological activity. One type of biological activity that is shown is an antiviral activity.
-
公开(公告)号:US20070054377A1
公开(公告)日:2007-03-08
申请号:US11550873
申请日:2006-10-19
申请人: Lowell Brady , Kevin Klucher , Chung Chan , Dennis Dong , Hong Liu , Paul Sheppard , Thomas Bukowski
发明人: Lowell Brady , Kevin Klucher , Chung Chan , Dennis Dong , Hong Liu , Paul Sheppard , Thomas Bukowski
CPC分类号: A61K38/20 , A61K38/00 , C07K14/54 , C07K14/555 , C07K2319/00 , Y10S435/81 , Y10S435/975 , Y10S514/894
摘要: Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor or exhibit biological activity. One type of biological activity that is shown is an antiviral activity.
-
-
-
-
-
-
-
-
-