公开(公告)号：US08602992B2

公开(公告)日：2013-12-10

申请号：US12887465

申请日：2010-09-21

申请人： Rajiv Shah ,  Wayne A. Morgan ,  David Y. Choy ,  James L. Henke ,  Bahar Reghabi ,  Gopikrishnan Soundararajan ,  Peter Schultz ,  Udo Hoss

发明人： Rajiv Shah ,  Wayne A. Morgan ,  David Y. Choy ,  James L. Henke ,  Bahar Reghabi ,  Gopikrishnan Soundararajan ,  Peter Schultz ,  Udo Hoss

IPC分类号： A61B5/05 ,  A61B5/00

CPC分类号： G01N27/403 ,  A61B5/14532 ,  A61B5/1473 ,  A61B2560/0223 ,  A61B2562/02 ,  C12Q1/006 ,  G01N27/327 ,  G01N27/416

摘要： A sensor system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes a connection detection device, a power source, and a delay circuit. The connection detection device determines if the sensor electronics device is connected to the sensor and transmits a connection signal. The delay circuit receives the connection signal, waits a preset hydration time, and couples the regulated voltage from the power source to an electrode in the sensor after the preset hydration time has elapsed. Alternatively, the sensor electronics device may include an electrical detection circuit and a microcontroller. The electrical detection circuit determines if the plurality of electrodes are hydrated and generates an interrupt if the electrodes are hydrated. A microcontroller receives the interrupt and transmits a signal representative of a voltage to an electrode of the plurality of electrodes.

摘要翻译： 传感器系统包括传感器和传感器电子设备。 传感器包括多个电极。 传感器电子设备包括连接检测装置，电源和延迟电路。 连接检测装置确定传感器电子设备是否连接到传感器并发送连接信号。 延迟电路接收连接信号，等待预设的水合时间，并且在经过预设水合时间之后将调节的电压从电源耦合到传感器中的电极。 或者，传感器电子设备可以包括电检测电路和微控制器。 电检测电路确定多个电极是否水合，并且如果电极是水合的则产生中断。 微控制器接收中断，并将代表电压的信号传送到多个电极的电极。

公开(公告)号：US08532732B2

公开(公告)日：2013-09-10

申请号：US12887449

申请日：2010-09-21

申请人： Rajiv Shah ,  Wayne A. Morgan ,  David Y. Choy ,  James L. Henke ,  Bahar Reghabi ,  Gopikrishnan Soundararajan ,  Peter Schultz ,  Udo Hoss

发明人： Rajiv Shah ,  Wayne A. Morgan ,  David Y. Choy ,  James L. Henke ,  Bahar Reghabi ,  Gopikrishnan Soundararajan ,  Peter Schultz ,  Udo Hoss

IPC分类号： A61B5/05

CPC分类号： G01N27/403 ,  A61B5/14532 ,  A61B5/1473 ,  A61B2560/0223 ,  A61B2562/02 ,  C12Q1/006 ,  G01N27/327 ,  G01N27/416

摘要： A sensor system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes a connection detection device, a power source, and a delay circuit. The connection detection device determines if the sensor electronics device is connected to the sensor and transmits a connection signal. The delay circuit receives the connection signal, waits a preset hydration time, and couples the regulated voltage from the power source to an electrode in the sensor after the preset hydration time has elapsed. Alternatively, the sensor electronics device may include an electrical detection circuit and a microcontroller. The electrical detection circuit determines if the plurality of electrodes are hydrated and generates an interrupt if the electrodes are hydrated. A microcontroller receives the interrupt and transmits a signal representative of a voltage to an electrode of the plurality of electrodes.

公开(公告)号：US20110125446A1

公开(公告)日：2011-05-26

申请号：US13004646

申请日：2011-01-11

申请人： RAJIV SHAH ,  Bahar Reghabi ,  James L. Henke ,  Wayne A. Morgan ,  Gopikrishnan Soundararajan ,  David Y. Choy ,  Peter Schultz ,  Udo Hoss

发明人： RAJIV SHAH ,  Bahar Reghabi ,  James L. Henke ,  Wayne A. Morgan ,  Gopikrishnan Soundararajan ,  David Y. Choy ,  Peter Schultz ,  Udo Hoss

IPC分类号： G06F19/00 ,  G01R35/00

CPC分类号： A61B5/1495 ,  A61B5/14532 ,  A61B5/14865 ,  A61B5/4839 ,  A61B2560/0223 ,  A61M5/1723 ,  A61M2230/201 ,  G01N27/327 ,  G01N27/3274

摘要： A blood glucose sensing system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes stabilization circuitry. The stabilization circuitry causes a first voltage to be applied to one of the electrodes for a first timeframe and causes a second voltage to be applied to one of the electrodes for a second timeframe. The stabilization circuitry repeats the application of the first voltage and the second voltage to continue the anodic—cathodic cycle. The sensor electronics device may include a power supply, a regulator, and a voltage application device, where the voltage application device receives a regulated voltage from the regulator, applies a first voltage to an electrode for the first timeframe, and applies a second voltage to an electrode for the second timeframe.

摘要翻译： 血糖感测系统包括传感器和传感器电子设备。 传感器包括多个电极。 传感器电子设备包括稳定电路。 稳定电路使得第一电压被施加到第一时间帧中的一个电极，并且使得第二电压被施加到第二时间范围中的一个电极。 稳定电路重复施加第一电压和第二电压以继续阳极 - 阴极循环。 传感器电子设备可以包括电源，调节器和电压施加装置，其中电压施加装置从调节器接收调节电压，在第一时间帧向电极施加第一电压，并施加第二电压 第二时间段的电极。

公开(公告)号：US20110010104A1

公开(公告)日：2011-01-13

申请号：US12887457

申请日：2010-09-21

申请人： RAJIV SHAH ,  Wayne A. Morgan ,  David Y. Choy ,  James L. Henke ,  Bahar Reghabi ,  Gopikrishnan Soundararajan ,  Peter Schultz ,  Udo Hoss

发明人： RAJIV SHAH ,  Wayne A. Morgan ,  David Y. Choy ,  James L. Henke ,  Bahar Reghabi ,  Gopikrishnan Soundararajan ,  Peter Schultz ,  Udo Hoss

IPC分类号： G06F19/00 ,  G01N33/48

CPC分类号： G01N27/403 ,  A61B5/14532 ,  A61B5/1473 ,  A61B2560/0223 ,  A61B2562/02 ,  C12Q1/006 ,  G01N27/327 ,  G01N27/416

摘要： A sensor system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes a connection detection device, a power source, and a delay circuit. The connection detection device determines if the sensor electronics device is connected to the sensor and transmits a connection signal. The delay circuit receives the connection signal, waits a preset hydration time, and couples the regulated voltage from the power source to an electrode in the sensor after the preset hydration time has elapsed. Alternatively, the sensor electronics device may include an electrical detection circuit and a microcontroller. The electrical detection circuit determines if the plurality of electrodes are hydrated and generates an interrupt if the electrodes are hydrated. A microcontroller receives the interrupt and transmits a signal representative of a voltage to an electrode of the plurality of electrodes.

公开(公告)号：US20070169533A1

公开(公告)日：2007-07-26

申请号：US11323242

申请日：2005-12-30

申请人： Rajiv Shah ,  Wayne A. Morgan ,  David Y. Choy ,  James L. Henke ,  Bahar Reghabi ,  Gopikrishnan Soundararajan ,  Peter Schultz ,  Udo Hoss

发明人： Rajiv Shah ,  Wayne A. Morgan ,  David Y. Choy ,  James L. Henke ,  Bahar Reghabi ,  Gopikrishnan Soundararajan ,  Peter Schultz ,  Udo Hoss

IPC分类号： G01D18/00 ,  A61B5/05 ,  A61B5/00

CPC分类号： G01N27/403 ,  A61B5/14532 ,  A61B5/1473 ,  A61B2560/0223 ,  A61B2562/02 ,  C12Q1/006 ,  G01N27/327 ,  G01N27/416

摘要： A sensor system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes a connection detection device, a power source, and a delay circuit. The connection detection device determines if the sensor electronics device is connected to the sensor and transmits a connection signal. The delay circuit receives the connection signal, waits a preset hydration time, and couples the regulated voltage from the power source to an electrode in the sensor after the preset hydration time has elapsed. Alternatively, the sensor electronics device may include an electrical detection circuit and a microcontroller. The electrical detection circuit determines if the plurality of electrodes are hydrated and generates an interrupt if the electrodes are hydrated. A microcontroller receives the interrupt and transmits a signal representative of a voltage to an electrode of the plurality of electrodes.

摘要翻译： 传感器系统包括传感器和传感器电子设备。 传感器包括多个电极。 传感器电子设备包括连接检测装置，电源和延迟电路。 连接检测装置确定传感器电子设备是否连接到传感器并发送连接信号。 延迟电路接收连接信号，等待预设的水合时间，并且在经过预设水合时间之后将调节的电压从电源耦合到传感器中的电极。 或者，传感器电子设备可以包括电检测电路和微控制器。 电检测电路确定多个电极是否水合，并且如果电极是水合的则产生中断。 微控制器接收中断，并将代表电压的信号传送到多个电极的电极。

公开(公告)号：US08216434B2

公开(公告)日：2012-07-10

申请号：US12041577

申请日：2008-03-03

申请人： Tzung K. Hsiai ,  Gopikrishnan Soundararajan ,  Eun Sok Kim ,  Hongyu Yu ,  Mahsa Rouhanizadeh ,  Christina Tiantian Lin

发明人： Tzung K. Hsiai ,  Gopikrishnan Soundararajan ,  Eun Sok Kim ,  Hongyu Yu ,  Mahsa Rouhanizadeh ,  Christina Tiantian Lin

IPC分类号： C23C14/34

CPC分类号： B81C1/00246 ,  G01N3/24

摘要： A micromachined sensor for measuring vascular parameters, such as fluid shear stress, includes a substrate having a front-side surface, and a backside surface opposite the front-side surface. The sensor includes a diaphragm overlying a cavity etched within the substrate, and a heat sensing element disposed on the front-side surface of the substrate and on top of the cavity and the diaphragm. The heat sensing element is electrically couplable to electrode leads formed on the backside surface of the substrate. The sensor includes an electronic system connected to the backside surface and configured to measure a change in heat convection from the sensing element to surrounding fluid when the sensing element is heated by applying an electric current thereto, and further configured to derive from the change in heat convection vascular parameters such as the shear stress of fluid flowing past the sensing element.

摘要翻译： 用于测量诸如流体剪切应力的血管参数的微加工传感器包括具有前侧表面的基底和与前侧表面相对的背侧表面。 传感器包括覆盖在衬底内蚀刻的空腔的膜片，以及设置在衬底的前侧表面上并且在空腔和隔膜顶部上的感热元件。 热敏元件可电连接到形成在基板的背面上的电极引线。 所述传感器包括连接到所述背面的电子系统，并且被配置为当通过向其施加电流来加热所述感测元件时，测量从所述感测元件到周围流体的热对流变化，并进一步被配置为从热变化 对流血管参数，例如流过感测元件的流体的剪切应力。

公开(公告)号：US20060081064A1

公开(公告)日：2006-04-20

申请号：US11196849

申请日：2005-08-04

申请人： Tzung Hsiai ,  Gopikrishnan Soundararajan ,  E. Kim ,  Hongyu Yu ,  Mahsa Rouhanizadeh ,  Tiantian Lin

发明人： Tzung Hsiai ,  Gopikrishnan Soundararajan ,  E. Kim ,  Hongyu Yu ,  Mahsa Rouhanizadeh ,  Tiantian Lin

IPC分类号： G01N3/24

CPC分类号： B81C1/00246 ,  G01N3/24

摘要： A micromachined sensor for measuring vascular parameters, such as fluid shear stress, includes a substrate having a front-side surface, and a backside surface opposite the front-side surface. The sensor includes a diaphragm overlying a cavity etched within the substrate, and a heat sensing element disposed on the front-side surface of the substrate and on top of the cavity and the diaphragm. The heat sensing element is electrically couplable to electrode leads formed on the backside surface of the substrate. The sensor includes an electronic system connected to the backside surface and configured to measure a change in heat convection from the sensing element to surrounding fluid when the sensing element is heated by applying an electric current thereto, and further configured to derive from the change in heat convection vascular parameters such as the shear stress of fluid flowing past the sensing element.

摘要翻译： 用于测量诸如流体剪切应力的血管参数的微加工传感器包括具有前侧表面的基底和与前侧表面相对的背侧表面。 传感器包括覆盖在衬底内蚀刻的空腔的膜片，以及设置在衬底的前侧表面上并且在空腔和隔膜顶部上的感热元件。 热敏元件可电连接到形成在基板的背面上的电极引线。 所述传感器包括连接到所述背面的电子系统，并且被配置为当通过向其施加电流来加热所述感测元件时，测量从所述感测元件到周围流体的热对流变化，并进一步被配置为从热变化 对流血管参数，例如流过感测元件的流体的剪切应力。

公开(公告)号：US20120215121A1

公开(公告)日：2012-08-23

申请号：US13461716

申请日：2012-05-01

申请人： Tzung K. Hsiai ,  Gopikrishnan Soundararajan ,  Eun Sok Kim ,  Hongyu Yu ,  Mahsa Rouhanizadeh ,  Christina Tiantian Lin

发明人： Tzung K. Hsiai ,  Gopikrishnan Soundararajan ,  Eun Sok Kim ,  Hongyu Yu ,  Mahsa Rouhanizadeh ,  Christina Tiantian Lin

IPC分类号： A61B5/027

CPC分类号： B81C1/00246 ,  G01N3/24

摘要： A micromachined sensor for measuring vascular parameters, such as fluid shear stress, includes a substrate having a front-side surface, and a backside surface opposite the front-side surface. The sensor includes a diaphragm overlying a cavity etched within the substrate, and a heat sensing element disposed on the front-side surface of the substrate and on top of the cavity and the diaphragm. The heat sensing element is electrically couplable to electrode leads formed on the backside surface of the substrate. The sensor includes an electronic system connected to the backside surface and configured to measure a change in heat convection from the sensing element to surrounding fluid when the sensing element is heated by applying an electric current thereto, and further configured to derive from the change in heat convection vascular parameters such as the shear stress of fluid flowing past the sensing element.

摘要翻译： 用于测量诸如流体剪切应力的血管参数的微加工传感器包括具有前侧表面的基底和与前侧表面相对的背侧表面。 传感器包括覆盖在衬底内蚀刻的空腔的膜片，以及设置在衬底的前侧表面上并且在空腔和隔膜顶部上的感热元件。 热敏元件可电连接到形成在基板的背面上的电极引线。 所述传感器包括连接到所述背面的电子系统，并且被配置为当通过向其施加电流来加热所述感测元件时，测量从所述感测元件到周围流体的热对流变化，并进一步被配置为从热变化 对流血管参数，例如流过感测元件的流体的剪切应力。