公开(公告)号：US20240341643A1

公开(公告)日：2024-10-17

申请号：US18752091

申请日：2024-06-24

Applicant: Roche Diabetes Care, Inc.

Inventor： Helmut Walter

IPC: A61B5/1473 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1486 ,  B08B5/00 ,  B08B7/00

CPC classification number: A61B5/1473 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/14865 ,  A61B5/6849 ,  B08B5/00 ,  B08B7/0035 ,  A61B5/688 ,  A61B2560/063 ,  A61B2562/166 ,  A61B2562/242

Abstract: Medical devices and methods are disclosed for detecting an analyte in a body fluid. The medical device comprises an analyte sensor having an insertable portion adapted for insertion into body tissue of a user. An insertion cannula receives the analyte sensor therein. A housing forms a sealed sensor compartment receiving an insertable portion of the analyte sensor. The sealed sensor compartment comprises a detachable upper cap and a detachable lower cap. The detachable lower cap is configured for detachment before sensor insertion. The cannula is attached to the detachable upper cap, wherein the detachable upper cap is configured for detachment after insertion, thereby removing the insertion cannula. The analyte sensor is operably connected to an electronics unit comprising an interconnect device with at least one electronic component attached thereto

公开(公告)号：US12114975B2

公开(公告)日：2024-10-15

申请号：US16728652

申请日：2019-12-27

Applicant: DexCom, Inc.

Inventor： Sebastian Bohm ,  Anna Claire Harley-Trochimczyk ,  Daiting Rong ,  Rui Ma ,  Wenjie Lan ,  Minglian Shi ,  Disha B. Sheth

IPC: A61B5/1495 ,  A61B5/00 ,  A61B5/0537 ,  A61B5/145 ,  A61B5/1473 ,  A61B5/1486 ,  G01N27/02 ,  G01N27/22 ,  G01N27/24 ,  G01N33/487

CPC classification number: A61B5/1495 ,  A61B5/0537 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/14865 ,  A61B5/6844 ,  G01N27/221 ,  G01N27/24 ,  G01N33/48707 ,  A61B5/0004 ,  A61B5/0031 ,  A61B2560/0223 ,  A61B2560/0252 ,  A61B2560/0276 ,  G01N27/026

Abstract: Various examples are directed to systems and methods for operating an analyte sensor system using sensor electronics. An example method may comprise applying a bias voltage change to an analyte sensor bias voltage and measuring a current value for each of a plurality of time periods after application of the bias voltage change. The example method may also comprise determining an estimated impedance using the current values for the plurality of time periods and determining a characteristic of the analyte sensor using the estimated impedance. The example method may further comprise receiving from the analyte sensor a signal indicative of an analyte concentration, and determining an estimated analyte concentration level using the determined characteristic of the analyte sensor and the received signal.

公开(公告)号：US12089932B2

公开(公告)日：2024-09-17

申请号：US17570235

申请日：2022-01-06

Applicant: Trace Matters Scientific LLC

Inventor： Mazdak Taghioskoui

IPC: A61B5/1473 ,  A61B5/00 ,  A61B10/04 ,  G01N27/622 ,  G01N33/483 ,  H01J49/00 ,  H01J49/06 ,  H01J49/16 ,  H01J49/36 ,  H01J49/42 ,  A61B18/00 ,  A61B18/24

CPC classification number: A61B5/1473 ,  A61B5/4842 ,  A61B10/04 ,  G01N27/622 ,  G01N33/4833 ,  H01J49/0013 ,  H01J49/0031 ,  H01J49/065 ,  H01J49/164 ,  H01J49/165 ,  H01J49/36 ,  H01J49/4235 ,  A61B2018/00577 ,  A61B18/24 ,  A61B2218/007 ,  A61B2503/40

Abstract: An ion transfer device that includes first and second ion guides, one or more RF voltage sources, and one or more DC voltage sources that produce first and second potential gradients in the first and second ion guides such that the potential gradients push the ions to move toward the outlet of each ion guide such that the one or more DC voltages produce a potential barrier, the potential barrier preventing the ions in the first ion guide from entering the second ion guide, the ions accumulate behind the potential barrier and form an ion packet, and the potential barrier is reduced after a predetermined time period to move the ion packet from the first ion guide to the second ion guide.

公开(公告)号：US20240293050A1

公开(公告)日：2024-09-05

申请号：US18646451

申请日：2024-04-25

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  Minglian Shi ,  Sebastian Bohm ,  Maria Noel Brown Wells ,  John Patrick Majewski ,  Leah Morta Edra ,  Disha B. Sheth ,  John Michael Gray ,  Shanger Wang ,  Ted Tang Lee ,  Michael L. Moore ,  Jason Mitchell ,  Jennifer Blackwell ,  Neel Narayan Shah ,  Todd Andrew Newhouse ,  Jason Halac ,  Ryan Everett Schoonmaker ,  Paul V. Neale ,  Jiong Zou ,  Sean T. Saint

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/1473 ,  A61B5/1486

CPC classification number: A61B5/14532 ,  A61B5/14503 ,  A61B5/683 ,  A61B5/6833 ,  A61B5/0004 ,  A61B5/0015 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/6849 ,  A61B2560/045

Abstract: Sensor systems can be used to measure an analyte concentration. Sensor systems can include a base having a distal side configured to face towards a person's skin. An adhesive can couple the base to the skin. A transcutaneous analyte measurement sensor can be coupled to the base and can be located at least partially in the host. A transmitter can be coupled to the base and can transmit analyte measurement data to a remote device.

公开(公告)号：US12070313B2

公开(公告)日：2024-08-27

申请号：US18347522

申请日：2023-07-05

Applicant: Biolinq Incorporated

Inventor： Daniel Alonso-Soski ,  Anderson Micu ,  Yan Li ,  Christopher Griffith ,  Jennifer Ruth Walters Fuchs

IPC: A61B5/1473 ,  A61B5/00 ,  A61B5/145

CPC classification number: A61B5/1473 ,  A61B5/685 ,  A61B5/14532 ,  A61B2560/0219

Abstract: Aspects of the current subject matter are directed to a sensor assembly of an analyte monitoring device including one or more microneedle arrays. Aspects are directed to components and architecture of a sensor assembly to implement power and processing aspects of a microneedle array-based continuous analyte monitoring device for the detection and measuring of an analyte. A source of a power-on event is determined, and the analyte monitoring device is transitioned to a mode that corresponds to the determined source. When a power-on event is determined to be a valid power-on event, the analyte monitoring device is transition to a mode that corresponds to a type of the valid power-on event.

公开(公告)号：US12029554B2

公开(公告)日：2024-07-09

申请号：US17822505

申请日：2022-08-26

Applicant: Abbott Diabetes Care Inc.

Inventor： Udo Hoss ,  Phu Le ,  Yi Wang ,  Frank David Fujimoto ,  Suyue Qian ,  Lam Tran

IPC: A61B5/145 ,  A61B5/1473 ,  C12Q1/00

CPC classification number: A61B5/14532 ,  A61B5/1473 ,  C12Q1/001 ,  C12Q1/006

Abstract: Embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have a sensing surface that includes two or more sensing elements disposed laterally to each other, where the sensing surface is on a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.

公开(公告)号：US20240215904A1

公开(公告)日：2024-07-04

申请号：US18684137

申请日：2022-08-23

Applicant: University of Cincinnati

Inventor： Jason Heikenfeld

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1473

CPC classification number: A61B5/4306 ,  A61B5/1451 ,  A61B5/1473

Abstract: A device for measuring one or more analytes in a sample of interstitial fluid or blood is provided. The device comprises at least one EAB sensor using one or more attached redox couples that measure at least one of the analytes. It also includes at least one means to establish fluid communication between the sensor and the sample. The analytes are selected from the group consisting of progesterone, luteinizing hormone (LH), estrogen, follicle stimulating hormone (FSH), their metabolites, and combinations thereof.

公开(公告)号：US20240215873A1

公开(公告)日：2024-07-04

申请号：US18684114

申请日：2022-08-22

Applicant: University of Cincinnati

Inventor： Jason Heikenfeld ,  Israel Belmonte ,  Ryan Jeffrey White

IPC: A61B5/145 ,  A61B5/1459 ,  A61B5/1473 ,  G01N27/27 ,  G01N27/327 ,  G01N33/53 ,  G01N33/543

CPC classification number: A61B5/14546 ,  A61B5/1459 ,  A61B5/1473 ,  G01N27/27 ,  G01N27/3276 ,  G01N27/3277 ,  G01N33/5308 ,  G01N33/5438 ,  A61B2560/0252

Abstract: A device for measuring one or more analytes in a sample fluid is provided. The device includes at least one aptamer sensor comprising a plurality of aptamers. The sensor provides a measurement of at least one of the analytes. In addition, the measurement is affected by changes in temperature (“a temperature-dependent response”). The device also includes a means to establish fluid communication between the at least one aptamer sensor and the sample fluid. Further, the device includes at least one temperature sensor and a means for correcting a measurement error due to the temperature-dependent response.

公开(公告)号：US20240206771A1

公开(公告)日：2024-06-27

申请号：US18599104

申请日：2024-03-07

Applicant: Bionime Corporation

Inventor： Chun-Mu Huang ,  Chieh-Hsing Chen ,  Heng-Chia Chang ,  Chi-Hao Chen ,  Pi-Hsuan Chen

IPC: A61B5/145 ,  A61B5/1473 ,  A61B5/1486

CPC classification number: A61B5/14503 ,  A61B5/1451 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/14735 ,  A61B5/14865 ,  A61B2560/0223 ,  A61B2560/0468 ,  A61B2562/0215 ,  A61B2562/028 ,  A61B2562/125 ,  A61B2562/16

Abstract: The present invention provides a micro biosensor for reducing a measurement interference when measuring a target analyte in the biofluid, including: a substrate; a first working electrode configured on the surface, and including a first sensing section; a second working electrode configured on the surface, and including a second sensing section which is configured adjacent to at least one side of the first sensing section; and a chemical reagent covered on at least a portion of the first sensing section for reacting with the target analyte to produce a resultant. When the first working electrode is driven by a first working voltage, the first sensing section measures a physiological signal with respect to the target analyte. When the second working electrode is driven by a second working voltage, the second conductive material can directly consume the interferant so as to continuously reduce the measurement inference of the physiological signal.

公开(公告)号：US12016648B2

公开(公告)日：2024-06-25

申请号：US16802399

申请日：2020-02-26

Applicant: DexCom, Inc.

Inventor： Mark C. Brister ,  Jack Pryor ,  John Nolting ,  Jacob S. Leach ,  Luis Pestana ,  Nelson Quintana ,  Vance Swanson ,  Paul V. Goode, Jr. ,  James Patrick Thrower

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/15 ,  G16Z99/00

CPC classification number: A61B5/0022 ,  A61B5/1411 ,  A61B5/14507 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/14865 ,  A61B5/150534 ,  A61B5/6832 ,  A61B5/6833 ,  A61B5/6848 ,  A61B5/6849 ,  A61B5/742 ,  G16Z99/00 ,  A61B5/0002 ,  A61B5/150022 ,  A61B2560/0214 ,  A61B2560/0223 ,  A61B2562/08 ,  Y02A90/10

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.