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公开(公告)号:US20190127399A1
公开(公告)日:2019-05-02
申请号:US16228130
申请日:2018-12-20
发明人: Robert Yongxin ZHAO , Xing LI , Yuangyuang HUANG , Qingliang YANG
IPC分类号: C07F9/30 , C07F9/572 , C07F9/6558 , A61K47/68 , C07F9/6561 , C07F9/32 , A61K38/07 , C07F9/58
摘要: Cell binding agent-drug conjugates comprising phosphinate-based charged linkers and methods of using such linkers and conjugates are provided.