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公开(公告)号：US20240189143A1
公开(公告)日：2024-06-13
申请号：US18583268
申请日：2024-02-21
发明人： Yehuda Ivri
CPC分类号： A61F9/0008 , A61B2017/00057 , A61B2017/00889
摘要： Multi-dose preservative-free ocular fluid delivery devices are provided. The fluid delivery device includes a fluid dispensing system and a fluid package for storing a liquid therein and supplying said liquid to the dispensing system. The dispensing system comprises an elongated chamber which includes a check valve which defines a frontal closure to the chamber. The valve is normally closed and hermetically seals the chamber. The dispenser includes a vibration motor that induces oscillations to the chamber and to the fluid within. The oscillations of the chamber impart momentum to the fluid stored in the chamber which in turn imparts force that cyclically opens the valve to dispense streams or liquid droplets. Fluid is dispensed only when the motor oscillates while otherwise the valve is hermetically closed.
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32.发明公开公开(公告)号：US20240142801A1
公开(公告)日：2024-05-02
申请号：US18409320
申请日：2024-01-10
发明人： Kristen Hovinga , Mohammad Musleh , Mengchen Xu
IPC分类号： G02C7/04
摘要： An ophthalmic lens, comprising a central zone having at least a first power, and a peripheral zone having an add-power offset relative to the at least first power and a spatially-modulated optical parameter. In some embodiments, the central zone has a diameter in the range 2.0 to 5.0 mm. In some embodiments, the central zone is not more than 1 mm smaller than a wearer's pupil. The spatially-modulated optical parameter may include optical power, light scattering or light transmission.
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公开(公告)号：US20230159202A1
公开(公告)日：2023-05-25
申请号：US17533978
申请日：2021-11-23
发明人： David J. Heiler
CPC分类号： B65B25/008 , B65B55/14 , B65B55/22
摘要： A preservative-free, sterile packaged ophthalmic device product is disclosed. The preservative-free, sterile packaged ophthalmic device product is obtained by (a) adding at least one polyquaternium polymer to an aqueous packaging solution for preventing antimicrobial contamination during storage; (b) packaging the aqueous packaging solution and an ophthalmic device in a manner preventing contamination of the ophthalmic device by one or more microorganisms; and (c) heat sterilizing the aqueous packaging solution and the ophthalmic device, whereby the at least one polyquaternium polymer decomposes during the heat sterilizing to obtain the preservative-free packaged ophthalmic device product.
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公开(公告)号：US20230045046A1
公开(公告)日：2023-02-09
申请号：US17397496
申请日：2021-08-09
发明人： Michael MOOREHEAD
IPC分类号： B65D75/32
摘要： A contact lens package includes a base including an upper surface and a receptacle having a volume. The contact lens package also includes a flexible cover including an interior surface that is coupled to the upper surface of the base. A stiff dome is attached to an interior surface of the cover and the stiff dome displaces an amount of volume from the volume of the receptacle. The contact lens package may also include a lens having an anterior surface and a posterior surface disposed in the receptacle with the posterior surface of the lens disposed adjacent to the stiff dome. By peeling the flexible cover away from the base, the lens remains mounted on the stiff dome causing the anterior surface of the lens to be presented to a user.
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公开(公告)号：US20230000679A1
公开(公告)日：2023-01-05
申请号：US17365353
申请日：2021-07-01
发明人： Christopher KOCHER , Jason TAYLOR , Elijah KESSLER
IPC分类号： A61F9/007
摘要： A phacoemulsification handpiece is provided for ophthalmic surgery. The phacoemulsification handpiece includes a housing having a cavity positioned at a distal end of the housing. The phacoemulsification handpiece further includes a horn positioned within the cavity. An irrigation line is coupled to the housing and is exterior to the housing. A port is coupled between the irrigation line and the cavity and the port is configured to direct fluid into the cavity to a side of the horn (e.g., without directly impinging on the horn, etc.).
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公开(公告)号：US20220411115A1
公开(公告)日：2022-12-29
申请号：US17714393
申请日：2022-04-06
发明人： Alok K. Awasthi , Jade J. Russell , Mark R. Mis
摘要： A packaging system for the storage of an ophthalmic device is disclosed. The packaging system includes a sealed container containing one or more unused ophthalmic devices immersed in an aqueous packaging solution that includes ectoine or an ophthalmologically acceptable ectoine derivative. The aqueous packaging solution has an osmolality of at least about 150 mOsm/kg, a pH of about 6 to about 9 and is sterilized.
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公开(公告)号：US20220298287A1
公开(公告)日：2022-09-22
申请号：US17694981
申请日：2022-03-15
发明人： Ivan M. Nuñez , Lynn Coullard , Katie L. Poetz
摘要： A biomedical device is disclosed which is a polymerization product of a mixture comprising (a) one or more difunctional isocyanates; (b) one or more polyalcohols; (c) one or more hydroxy-terminated polysiloxane prepolymers; and (d) one or more polyoxazoline polyols having a weight average molecular weight of equal to or greater than about 1000 Daltons.
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公开(公告)号：US20240245628A1
公开(公告)日：2024-07-25
申请号：US18402046
申请日：2024-01-02
发明人： Daniel STEIN , Christopher CORTINA
IPC分类号： A61K31/122 , A61K31/05 , A61K31/355 , A61K31/375 , A61K33/30 , A61K33/34 , A61K45/06
CPC分类号： A61K31/122 , A61K31/05 , A61K31/355 , A61K31/375 , A61K33/30 , A61K33/34 , A61K45/06
摘要： The present disclosure describes compositions comprising vitamin C, vitamin E, zinc, copper, lutein, zeaxanthin, and coenzyme Q10, and pharmaceutically acceptable salts of any of the foregoing. The compositions are useful in methods for treating conditions associated with a loss of visual acuity including, for example, age-related macular degeneration as well as supporting heart health.
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公开(公告)号：US20240238120A1
公开(公告)日：2024-07-18
申请号：US18435403
申请日：2024-02-07
发明人： Yehuda Ivri
CPC分类号： A61F9/0008 , B05B1/3006 , G02B5/10
摘要： Multi-dose preservative-free ocular fluid delivery devices are provided. The fluid delivery device includes a fluid dispensing system and a fluid package for storing a liquid therein and supplying said liquid to the dispensing system. The dispensing system comprises an elongated chamber which includes a check valve which defines a frontal closure to the chamber. The valve is normally closed and hermetically seals the chamber. The dispenser includes a vibration motor that induces oscillations to the chamber and to the fluid within. The oscillations of the chamber impart momentum to the fluid stored in the chamber which in turn imparts force that cyclically opens the valve to dispense streams or liquid droplets. Fluid is dispensed only when the motor oscillates while otherwise the valve is hermetically closed.
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公开(公告)号：US20240218291A1
公开(公告)日：2024-07-04
申请号：US18374208
申请日：2023-09-28
CPC分类号： C11D3/0078 , C11D3/046 , C11D3/222 , C11D3/30
摘要： A contact lens treating solution includes (a) one or more potassium salts selected from the group consisting of potassium chloride, potassium citrate, potassium hydroxide, potassium borate, potassium ethylenediaminetetraacetic acid and potassium phosphate, (b) an antimicrobial agent comprising alexidine or a salt or a free base thereof, and (c) optionally, one or more sodium salts selected from the group consisting of sodium chloride, sodium citrate, sodium hydroxide, sodium phosphate, sodium ethylenediaminetetraacetic acid and sodium borate, wherein the one or more potassium salts are present in an amount greater than an amount of the one or more sodium salts when present.
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