公开(公告)号：US12128057B2

公开(公告)日：2024-10-29

申请号：US17840332

申请日：2022-06-14

Applicant: Natals, Inc.

Inventor： Luke Bucci ,  Katerina Schneider ,  Mastaneh Sharafi ,  Nima Alamdari

IPC: A61K31/593 ,  A23D9/007 ,  A23L5/00 ,  A23L33/00 ,  A23L33/115 ,  A23L33/12 ,  A23L33/15 ,  A23L33/155 ,  A23L33/16 ,  A61K9/16 ,  A61K9/48 ,  A61K31/122 ,  A61K31/202 ,  A61K31/355 ,  A61K31/519 ,  A61K31/714 ,  A61K33/06 ,  A61K33/22 ,  A61K33/26 ,  A61K36/02 ,  A61K36/31 ,  B65D25/54 ,  B65D81/20

CPC classification number: A61K31/593 ,  A23D9/007 ,  A23L5/00 ,  A23L33/115 ,  A23L33/12 ,  A23L33/15 ,  A23L33/155 ,  A23L33/16 ,  A23L33/40 ,  A61K9/1652 ,  A61K9/1664 ,  A61K9/1676 ,  A61K9/4808 ,  A61K31/122 ,  A61K31/202 ,  A61K31/355 ,  A61K31/519 ,  A61K31/714 ,  A61K33/06 ,  A61K33/22 ,  A61K33/26 ,  A61K36/02 ,  A61K36/31 ,  B65D25/54 ,  B65D81/2076 ,  A23V2002/00 ,  B65D2203/12 ,  A23V2002/00 ,  A23V2200/224 ,  A23V2200/30 ,  A23V2250/1572 ,  A23V2250/1592 ,  A23V2250/161 ,  A23V2250/1642 ,  A23V2250/1882 ,  A23V2250/202 ,  A23V2250/5054 ,  A23V2250/51084 ,  A23V2250/702 ,  A23V2250/7056 ,  A23V2250/706 ,  A23V2250/71 ,  A23V2250/712 ,  A23V2250/714 ,  A23V2002/00 ,  A23V2200/224 ,  A23V2200/30 ,  A23V2250/1572 ,  A23V2250/1592 ,  A23V2250/161 ,  A23V2250/1882 ,  A23V2250/202 ,  A23V2250/5054 ,  A23V2250/51084 ,  A23V2250/7056 ,  A23V2250/706 ,  A23V2250/71 ,  A23V2250/712 ,  A23V2250/714

Abstract: Provided herein are dietary supplement compositions comprising a plurality of beadlets and an oil. Provided herein are also dietary supplement compositions comprising a plurality of mini-tabs and oil. The beadlets or mini-tabs comprise at least one nutrient that is miscible in aqueous solution, and the oil comprises at least one fat-soluble nutrient. The composition may be contained within one or more capsules, and be packaged with a scented insert.

公开(公告)号：US20240350429A1

公开(公告)日：2024-10-24

申请号：US18759705

申请日：2024-06-28

Applicant: QH Holdings (Oregon), Inc.

Inventor： James Stringham

IPC: A61K31/065 ,  A61K31/202 ,  A61K31/341 ,  A61K31/355 ,  A61K33/30 ,  A61K35/60 ,  A61K35/644 ,  A61K36/28 ,  A61K36/48 ,  A61K47/42 ,  A61P27/02

CPC classification number: A61K31/065 ,  A61K31/202 ,  A61K31/341 ,  A61K31/355 ,  A61K33/30 ,  A61K35/60 ,  A61K35/644 ,  A61K36/28 ,  A61K36/48 ,  A61K47/42 ,  A61P27/02

Abstract: An eye health supplement and methods of using the eye health supplement are disclosed.

公开(公告)号：US12109254B2

公开(公告)日：2024-10-08

申请号：US17945043

申请日：2022-09-14

Applicant: Edgar Lee Hull, Jr.

Inventor： Edgar Lee Hull, Jr. ,  Narashima Murthy ,  Sridhara Am

IPC: A61K38/44 ,  A61K31/122 ,  A61K31/197 ,  A61K31/198 ,  A61K31/355 ,  A61K31/405 ,  A61K31/4172 ,  A61K31/4415 ,  A61K31/455 ,  A61K31/51 ,  A61K31/519 ,  A61K31/525 ,  A61K31/714 ,  A61K33/00 ,  A61K33/04 ,  A61K33/30

CPC classification number: A61K38/443 ,  A61K31/122 ,  A61K31/197 ,  A61K31/198 ,  A61K31/355 ,  A61K31/405 ,  A61K31/4172 ,  A61K31/4415 ,  A61K31/455 ,  A61K31/51 ,  A61K31/519 ,  A61K31/525 ,  A61K31/714 ,  A61K33/00 ,  A61K33/04 ,  A61K33/30 ,  A61K38/446

Abstract: A low nitrogen protein food composition Albutrix™ for use by kidney patients in Stages 3, 4, 4a, 4b, and 5, who are not on dialysis, in a treatment program comprising administering daily a: low nitrogen diet; low nitrogen protein food comprising magnesium and/or calcium salts of alpha keto acids; and time released vitamin. The vitamin comprises the active ingredients of: Zinc; Selenium; Vitamins B1, B2, B6, B12, B5, E, and K2; Niacin; superoxide dismutase; catalase; glutathione and Folate; and excludes calcium, magnesium, phosphorus, sodium, manganese, fluoride, Vitamin D and K1. The low nitrogen food contains daily up to 300 mg of nitrogen; and at least five alpha keto analogues of magnesium and/or calcium salts of: leucine, isoleucine, methionine (MEMS-II), phenylalanine (PAMS-I), and valine. The treatment results in an increase of Glomerular Filtration Rate (GFR), a decrease in blood urea levels, and a decrease in creatinine levels.

公开(公告)号：US20240325292A1

公开(公告)日：2024-10-03

申请号：US18295188

申请日：2023-04-03

Applicant: Xygenyx Inc.

Inventor： Alexy Goldstein

IPC: A61K9/00 ,  A61K31/33 ,  A61K31/355 ,  A61K31/357 ,  A61K35/74 ,  A61K36/28 ,  A61K36/886

CPC classification number: A61K9/0014 ,  A61K31/33 ,  A61K31/355 ,  A61K31/357 ,  A61K35/74 ,  A61K36/28 ,  A61K36/886

Abstract: A composition comprising an aqueous gel with therapeutically effective amounts of carnosine, vitamin E, aloe vera gel, and a Silybum marianum extract. The extract of the Silybum marianum plants may be silymarin, and the addition of a therapeutically effective amount of a Lactobacillus ferment lysate may also be used.

公开(公告)号：US20240285549A1

公开(公告)日：2024-08-29

申请号：US18488736

申请日：2023-10-17

Applicant: Constance Therapeutics, Inc.

Inventor： Constance Finley ,  Haley Poole Bestwick

IPC: A61K31/05 ,  A61K31/192 ,  A61K31/352 ,  A61K31/355 ,  A61K36/185 ,  A61P35/00

CPC classification number: A61K31/05 ,  A61K31/192 ,  A61K31/352 ,  A61K31/355 ,  A61K36/185 ,  A61P35/00 ,  A61K2300/00

Abstract: The present invention provides Cannabis oil compositions, including Cannabis oil compositions containing vitamin E, and methods for preparing the Cannabis oil compositions. In some embodiments, the invention provides a method for preparing a Cannabis oil composition comprising eluting cannabinoids from Cannabis plant material with a solvent to produce an eluate; filtering the eluate with a filter to produce a filtrate; evaporating the solvent from the filtrate with a distiller to produce a distillate; and purging the distillate under conditions sufficient to remove residual solvent. In some embodiments, the method further includes mixing a quantity of vitamin E with the extract. Blended Cannabis oil compositions containing mixtures of Cannabis oil preparations are also described.

公开(公告)号：US20240261412A1

公开(公告)日：2024-08-08

申请号：US18564462

申请日：2022-05-30

Applicant: AKAY NATURAL INGREDIENTS PRIVATE LIMITED

Inventor： Krishnakumar ILLATHU MADHAVAMENON ,  Balu Paulose MALIAKEL

IPC: A61K47/36 ,  A61K9/107 ,  A61K31/047 ,  A61K31/05 ,  A61K31/07 ,  A61K31/122 ,  A61K31/352 ,  A61K31/355 ,  A61K31/375 ,  A61K31/409 ,  A61K31/4375 ,  A61K31/593 ,  A61K33/04 ,  A61K33/06 ,  A61K33/26 ,  A61K33/30

CPC classification number: A61K47/36 ,  A61K9/107 ,  A61K31/047 ,  A61K31/05 ,  A61K31/07 ,  A61K31/122 ,  A61K31/352 ,  A61K31/355 ,  A61K31/375 ,  A61K31/409 ,  A61K31/4375 ,  A61K31/593 ,  A61K33/04 ,  A61K33/06 ,  A61K33/26 ,  A61K33/30

Abstract: The present disclosure relates to a nutraceutical composition and a process for its preparation. The nutraceutical composition comprises a bioactive substance, galactomannan mixture for the delivery of hydrophilic and hydrophobic bioactive substances. The nutraceutical composition of the present disclosure provides stable composition and enhances the concentration and duration of a bioactive substance in the systemic circulation and its efficacy.

公开(公告)号：US20240245607A1

公开(公告)日：2024-07-25

申请号：US18426838

申请日：2024-01-30

Applicant: Temple University-Of The Commonwealth System of Higher Education

Inventor： Gregory S. Smutzer ,  Kevin Lee ,  Dhruti Patel

IPC: A61K9/16 ,  A61K9/00 ,  A61K31/01 ,  A61K31/015 ,  A61K31/047 ,  A61K31/12 ,  A61K31/165 ,  A61K31/192 ,  A61K31/353 ,  A61K31/355 ,  A61K31/366 ,  A61K31/704 ,  A61K36/185 ,  A61K47/10 ,  A61K47/22 ,  A61K47/24 ,  A61K47/26 ,  A61K47/36 ,  A61K47/38 ,  A61K47/46

CPC classification number: A61K9/1617 ,  A61K9/0056 ,  A61K9/1623 ,  A61K9/1682 ,  A61K31/01 ,  A61K31/015 ,  A61K31/047 ,  A61K31/12 ,  A61K31/165 ,  A61K31/192 ,  A61K31/353 ,  A61K31/355 ,  A61K31/366 ,  A61K31/704 ,  A61K36/185 ,  A61K47/10 ,  A61K47/22 ,  A61K47/24 ,  A61K47/26 ,  A61K47/36 ,  A61K47/38 ,  A61K47/46

Abstract: The present invention relates to compositions and methods for masking the taste of an agent. In certain aspects, the invention comprises a microsphere and at least one sweetener therein. In another aspect, the invention comprises an edible material comprising at least one microsphere comprising an agent and at least one microsphere comprising a sweetener.

公开(公告)号：US20240238289A1

公开(公告)日：2024-07-18

申请号：US18432824

申请日：2024-02-05

Applicant: Mayo Foundation for Medical Education and Research

Inventor： Karl A. Nath ,  James L. Kirkland ,  Tamar Tchkonia

IPC: A61K31/506 ,  A61K31/355 ,  A61P9/10

CPC classification number: A61K31/506 ,  A61K31/355 ,  A61P9/10

Abstract: This document provides methods and materials for improving arteriovenous fistula (AVF) maturation and/or maintaining AVF functionality. For example, methods and materials for using one or more senolytic agents to improve AVF maturation, to maintain AVF functionality, and/or to maintain the patency of an AVF are provided. Methods and materials for using one or more senolytic agents to maintain functionality and/or patency of a venous graft (e.g., a venous graft that bypasses an occluded artery) also are provided.

公开(公告)号：US20240226027A1

公开(公告)日：2024-07-11

申请号：US18409244

申请日：2024-01-10

Applicant: Nuecology Biomedical Inc.

Inventor： Chung Chin SUN ,  Dean Mo LIU

IPC: A61K9/51 ,  A61K9/00 ,  A61K31/07 ,  A61K31/12 ,  A61K31/337 ,  A61K31/355 ,  A61K31/4745 ,  A61K31/704 ,  A61P35/00 ,  C07K16/32

CPC classification number: A61K9/5161 ,  A61K9/0019 ,  A61K31/07 ,  A61K31/12 ,  A61K31/337 ,  A61K31/355 ,  A61K31/4745 ,  A61K31/704 ,  A61P35/00 ,  C07K16/32

Abstract: This invention discloses an injectable nanocomposite gel composition and the method of making the composition. The composition is composed of amphiphilic alginate nanoparticle, gel stabilizer, gel crosslinker, and gel structural modifiers. The nanocomposite gel can be manufactured into a form of highly-viscous gel or a solid-like gel, used as a vehicle to carry and deliver pharmaceutically active ingredients with high drug load via injection administration for medical uses.

公开(公告)号：US20240191250A1

公开(公告)日：2024-06-13

申请号：US18513227

申请日：2023-11-17

Applicant: RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL

Inventor： Louise Rodino-Klapac

IPC: C12N15/85 ,  A01K67/0276 ,  A61K31/122 ,  A61K31/355 ,  A61K45/06 ,  A61K48/00 ,  A61P21/00 ,  C07K14/435 ,  C07K14/47 ,  C07K14/705 ,  C12N15/86

CPC classification number: C12N15/8509 ,  A01K67/0276 ,  A61K31/122 ,  A61K31/355 ,  A61K45/06 ,  A61K48/005 ,  A61P21/00 ,  C07K14/435 ,  C07K14/4707 ,  C07K14/705 ,  C12N15/86 ,  A01K2217/075 ,  A01K2227/105 ,  A01K2267/0306 ,  C12N2015/8518 ,  C12N2015/8536 ,  C12N2750/14143 ,  C12N2830/008

Abstract: The invention provides for AAV vectors expressing the ANO5 gene and antioxidant therapy as methods of inducing muscle regeneration and a method of treating muscular dystrophy.