公开(公告)号：US20080174776A1

公开(公告)日：2008-07-24

申请号：US12000732

申请日：2007-12-17

Applicant: Takayuki Inoue ,  Tadashi Maruno ,  Fumio Iwase

Inventor： Takayuki Inoue ,  Tadashi Maruno ,  Fumio Iwase

IPC: G01N21/64

CPC classification number: G01N21/6456 ,  G01J3/2803 ,  G01J3/2823 ,  G01J3/2889 ,  G01J3/4406 ,  G01J2003/2813 ,  G01J2003/282 ,  G01N21/645 ,  G01N2021/6417 ,  G01N2021/6423 ,  H04N5/3454 ,  H04N5/372

Abstract: A fluorescence correlation spectroscopy analyzer 1 is equipped with an excitation light illuminating optical system 21, a fluorescence imaging optical system 22, a CCD camera 15, and a data analyzer 16. The excitation light illuminating optical system 21 illuminates excitation light onto a predetermined region of a measured sample S. The fluorescence imaging optical system 22 images the fluorescence generated at the measured sample S onto the photodetection surface of the CCD camera 15. The CCD camera 15 performs photoelectric conversion of the fluorescence made incident onto the photodetection surface in accordance with the respective pixels and outputs the charges generated by the photoelectric conversion as detection signals from an output terminal. The data analyzer 16 inputs the detection signals based on the charges generated at the pixels, among the pixels of the CCD camera 15, that belong to an analyzed pixel set and computes autocorrelation functions of the input detection signals according to each pixel. A fluorescence correlation spectroscopy analyzer, which is enabled to perform fluorescence correlation spectroscopy analysis on multiple points of a measured sample simultaneously and at high speed, is thus provided.

Abstract translation: 荧光相关光谱分析仪1配备有激发光照明光学系统21，荧光成像光学系统22，CCD照相机15和数据分析器16.激发光照射光学系统21将激发光照射到 测量样品S.荧光成像光学系统22将在测量样品S处产生的荧光图像成像到CCD照相机15的光电检测表面上。CCD照相机15根据照相机15对入射到光电检测表面上的荧光进行光电转换 并输出由光电转换产生的电荷作为来自输出端的检测信号。 数据分析器16基于在CCD摄像机15的像素中产生的属于分析像素组的像素产生的电荷输入检测信号，并根据每个像素计算输入检测信号的自相关函数。 因此，提供了可以同时进行高速度地对多个点进行荧光相关光谱分析的荧光相关光谱分析仪。

公开(公告)号：US20050205758A1

公开(公告)日：2005-09-22

申请号：US10804005

申请日：2004-03-19

Applicant: Leo Almeida

Inventor： Leo Almeida

IPC: G01J1/42 ,  G01J3/28 ,  H01J5/16

CPC classification number: G01J3/2803 ,  G01J3/2823 ,  G01J2003/282

Abstract: A multispectral photodetector array includes a two-dimensional array of photodetectors, either photodiodes or photoconductors, are coupled to a read out integrated circuit. The integrated circuit collects electrical signals from individual pixels of the array. Such an array differs from a conventional array in that each row or group of rows in the array has a distinct spectral response.

Abstract translation: 包括二维阵列的光电二极管或光电导体的多光谱光电检测器阵列耦合到读出的集成电路。 集成电路从阵列的各个像素收集电信号。 这种阵列与常规阵列不同之处在于阵列中的每行或一组行具有不同的光谱响应。