Fluorescent correalated spectrometric analysis device
    5.
    发明申请
    Fluorescent correalated spectrometric analysis device 有权
    荧光相关光谱分析装置

    公开(公告)号:US20060262301A1

    公开(公告)日:2006-11-23

    申请号:US10545393

    申请日:2004-02-13

    Abstract: A fluorescence correlation spectroscopy analyzer 1 is equipped with an excitation light illuminating optical system 21, a fluorescence imaging optical system 22, a CCD camera 15, and a data analyzer 16. The excitation light illuminating optical system 21 illuminates excitation light onto a predetermined region of a measured sample S. The fluorescence imaging optical system 22 images the fluorescence generated at the measured sample S onto the photodetection surface of the CCD camera 15. The CCD camera 15 performs photoelectric conversion of the fluorescence made incident onto the photodetection surface in accordance with the respective pixels and outputs the charges generated by the photoelectric conversion as detection signals from an output terminal. The data analyzer 16 inputs the detection signals based on the charges generated at the pixels, among the pixels of the CCD camera 15, that belong to an analyzed pixel set and computes autocorrelation functions of the input detection signals according to each pixel. A fluorescence correlation spectroscopy analyzer, which is enabled to perform fluorescence correlation spectroscopy analysis on multiple points of a measured sample simultaneously and at high speed, is thus provided.

    Abstract translation: 荧光相关光谱分析仪1配备有激发光照明光学系统21,荧光成像光学系统22,CCD照相机15和数据分析器16。 激发光照射光学系统21将激发光照射到测量样品S的预定区域上。荧光成像光学系统22将在测量样品S处产生的荧光图像到CCD照相机15的光电检测表面上。 CCD摄像机15根据各像素对入射到光检测面上的荧光进行光电转换,并将从光电转换产生的电荷作为检测信号从输出端子输出。 数据分析器16基于在CCD摄像机15的像素中产生的属于分析像素组的像素产生的电荷输入检测信号,并根据每个像素计算输入检测信号的自相关函数。 因此,提供了可以同时进行高速度地对多个点进行荧光相关光谱分析的荧光相关光谱分析仪。

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