公开(公告)号：US20060034914A1

公开(公告)日：2006-02-16

申请号：US11196799

申请日：2005-08-03

申请人： Joseph Tyler ,  John Petersen

发明人： Joseph Tyler ,  John Petersen

IPC分类号： A61K9/20

CPC分类号： A61K31/785 ,  A61K9/2009 ,  A61K9/2013 ,  A61K9/2027 ,  A61K9/28 ,  A61K9/282 ,  A61K9/2866

摘要： The present invention provides a tablet core which comprises at least about 95% by weight of an aliphatic amine polymer. The invention also provides a method of producing a tablet core comprising at least about 95% by weight of an aliphatic amine polymer resin The method comprises the step of compressing the aliphatic amine polymer to form the tablet core. The tablet core can further include one or more excipients. In this embodiment, the method of producing the tablet core comprises the steps of: (1) hydrating the aliphatic amine polymer to the desired moisture level; (2) blending the aliphatic amine polymer with the excipients in amounts such that the polymer comprises at least about 95% by weight of the resulting blend; and (3) compressing the blend to form the tablet core. The present invention further relates to a coated tablet comprising an aliphatic amine polymer core wherein the coating is a water based coating.

公开(公告)号：US20050260236A1

公开(公告)日：2005-11-24

申请号：US10405105

申请日：2003-03-31

申请人： Joseph Tyler ,  John Petersen

发明人： Joseph Tyler ,  John Petersen

IPC分类号： A61K9/00 ,  A61K9/20 ,  A61K9/28 ,  A61K31/785

CPC分类号： A61K31/785 ,  A61K9/2009 ,  A61K9/2013 ,  A61K9/2027 ,  A61K9/2045 ,  A61K9/2054 ,  A61K9/2095 ,  A61K9/282 ,  A61K9/2866

摘要： The present invention provides a tablet comprising a compressed tablet core which comprises at least about 80% by weight of an aliphatic amine polymer. The invention also provides a method of producing a tablet core comprising at least about 80% by weight of an aliphatic amine polymer resin. The method comprises the step of compressing the aliphatic amine polymer to form the tablet core. The tablet core can further include one or more excipients. In this embodiment, the method of producing the tablet core comprises the steps of: (1) hydrating the aliphatic amine polymer to the desired moisture level; (2) blending the aliphatic amine polymer with the excipients in amounts such that the polymer comprises at least about 80% by weight of the resulting blend; and (3) compressing the blend to form the tablet core. The present invention further relates to a coated tablet comprising an aliphatic amine polymer core wherein the coating is a water based coating.

摘要翻译： 本发明提供了包含压缩片芯的片剂，其包含至少约80重量％的脂族胺聚合物。 本发明还提供一种生产包含至少约80重量％的脂族胺聚合物树脂的片芯的方法。 该方法包括压缩脂族胺聚合物以形成片芯的步骤。 片芯可进一步包括一种或多种赋形剂。 在该实施方案中，制备片芯的方法包括以下步骤：（1）将脂族胺聚合物水合至期望的水分含量; （2）将脂族胺聚合物与赋形剂混合，使得聚合物包含至少约80重量％的所得共混物; 和（3）压缩混合物以形成片芯。 本发明还涉及一种包含脂族胺聚合物核心的包衣片剂，其中该涂料是水基涂料。

公开(公告)号：US4766065A

公开(公告)日：1988-08-23

申请号：US643403

申请日：1984-08-23

申请人： Larry Mosier ,  John Petersen

发明人： Larry Mosier ,  John Petersen

IPC分类号： A61K39/00 ,  C12Q1/00 ,  G01N33/569 ,  G01N33/53 ,  C12Q1/04

CPC分类号： G01N33/56927

摘要： The invention comprises a method for detecting cell proteins of microorganisms, such as the principal outer membrane protein of Chlamydia trachomatis having a mean molecular weight of 39,500 daltons. The method includes the steps of adding a buffer salt solution to a specimen suspected of containing bacterial antigens, raising the pH of the buffered solution so produced, incubating the solution, adding a neutralizing buffer to the solution to lower the pH, and assaying the sample by conventional immunoassay techniques. Optionally the sample solution is heated prior to incubation and then cooled afterwards before adding the neutralizing buffer.

摘要翻译： 本发明包括一种检测微生物细胞蛋白的方法，例如沙眼衣原体的主要外膜蛋白，其平均分子量为39,500道尔顿。 该方法包括以下步骤：向疑似含有细菌抗原的样品中加入缓冲盐溶液，提高如此制备的缓冲溶液的pH值，孵育溶液，向溶液中加入中和缓冲液以降低pH值，并测定样品 通过常规免疫测定技术。 任选地，将样品溶液在孵育之前加热，然后在加入中和缓冲液之前冷却。