公开(公告)号：US11033387B2

公开(公告)日：2021-06-15

申请号：US16378307

申请日：2019-04-08

申请人： Edwards Lifesciences Corporation

发明人： John J. Desrosiers ,  Amanda Kristine Anderson White ,  Michael R. Bialas ,  Gilbert Madrid ,  Michael J. Popp ,  Thanh V. Nguyen ,  Jun Liu ,  Asher L. Metchik ,  Darshin S. Patel

IPC分类号： A61F2/24

摘要： One method of implanting a prosthetic valve includes advancing the valve into a patient with a delivery apparatus. The valve includes apices circumferentially-spaced apart relative to each other. At least some of the apices include first apertures. The delivery apparatus includes release arms and a sheath. The release arms include second apertures for receiving the apices. At least one of the second apertures of the release arms has a different length than another one of the second apertures. The method also includes positioning the valve at a location, retracting a sheath of the delivery apparatus relative to the valve, allowing the valve to self-expand from a radially compressed state to a radially expanded state, and while the valve is coupled to the delivery apparatus, pivoting the valve relative about the release arms such that an axis of the valve is tilted relative to an axis of the delivery apparatus.

公开(公告)号：US10350047B2

公开(公告)日：2019-07-16

申请号：US15250759

申请日：2016-08-29

申请人： Edwards Lifesciences Corporation

发明人： Vipul P. Rajpara ,  Darshin S. Patel ,  Michael R. Bialas ,  Brian R. Lowry ,  Russ Hunton ,  Arvin T. Chang

IPC分类号： A61F2/24 ,  A61F2/00 ,  B65D1/34 ,  B65D77/26 ,  B65D43/02

摘要： A packaging system for storing a prosthetic valve and an elongated delivery system in a non-fluid environment. The packaging system includes a tray for securing both a prosthetic valve and an elongated delivery system. The tray includes a cavity sized and shaped to house a valve cover containing the prosthetic valve and at least part of the distal portion of the elongated delivery system. A mounting surface removably couples the valve cover to the cavity floor and to prevent the valve cover from moving. An engaging surface is disposed peripherally of the cavity and is elevated above the cavity floor. A ramp extends downwardly from the engaging surface and into the cavity through an opening defined in the peripheral side wall and adjacent the floor of the cavity. The engaging surface and ramp are configured to secure at least part of the elongated delivery system externally of the cavity.

公开(公告)号：US10314703B2

公开(公告)日：2019-06-11

申请号：US15263204

申请日：2016-09-12

申请人： Edwards Lifesciences Corporation

发明人： David Maimon ,  Michael R. Bialas ,  Mindy Lee Ann Black ,  Tamir S. Levi ,  Linda Thai ,  Yidong M. Zhu

IPC分类号： A61F2/24 ,  A61F2/958

摘要： Disclosed herein are embodiments of a balloon shaped to have one or more enlarged regions to selectively increase expansion forces on an implant. For example, the balloon may have a central portion that is enlarged to exert more force on the center of a stent-mounted prosthetic heart valve. This overcomes the stent-mounted prosthetic heart valve's tendency to expand with flared ends. This forms a more cylindrical or barrel shaped stent frame during expansion of the balloon—reducing or eliminating the instance wherein the cylindrical stent frame has flared ends. Alternatively, the balloon may have conical flares placed to cause or enhance flared ends of the cylindrical implant to enhance its anchoring capabilities.

公开(公告)号：US20190117937A1

公开(公告)日：2019-04-25

申请号：US16159966

申请日：2018-10-15

申请人： Edwards Lifesciences Corporation

发明人： Timothy Lee Humphrey ,  Michael R. Bialas

IPC分类号： A61M25/01

摘要： A steerable medical apparatus includes a shaft, a steering mechanism, and an actuation mechanism. The shaft has a proximal portion, a distal portion, a first pull wire, and a second pull wire. The distal ends of the first and second pull wires are coupled to the distal portion of the shaft. The steering mechanism has a first wheel and a second wheel coupled by a differential mechanism. The proximal ends of the first and second pull wires are respectively coupled to the first and second wheels. The actuation mechanism is coupled to the steering mechanism. Actuating the actuation mechanism in a first operational mode causes the distal portion of the shaft to curve in a first plane. Actuating the actuation mechanism in a second operational mode causes the distal portion of the shaft to curve away from the first plane.

公开(公告)号：US20170056149A1

公开(公告)日：2017-03-02

申请号：US15250759

申请日：2016-08-29

申请人： Edwards Lifesciences Corporation

发明人： Vipul P. Rajpara ,  Darshin S. Patel ,  Michael R. Bialas ,  Brian R. Lowry ,  Russ Hunton ,  Arvin T. Chang

IPC分类号： A61F2/00 ,  A61F2/24 ,  B65D43/02 ,  B65D1/34 ,  B65D77/26

CPC分类号： A61F2/0095 ,  A61F2/2412 ,  A61F2/2427 ,  A61F2240/001 ,  B65D1/34 ,  B65D43/02 ,  B65D77/26

摘要： A packaging system for storing a prosthetic valve and an elongated delivery system in a non-fluid environment. The packaging system comprises a tray for securing both a prosthetic valve and an elongated delivery system. The tray includes a cavity sized and shaped to house a valve cover containing the prosthetic valve and at least part of the distal portion of the elongated delivery system. A mounting surface removably couples the valve cover to the cavity floor and to prevent the valve cover from moving. An engaging surface is disposed peripherally of the cavity and is elevated above the cavity floor. A ramp extends downwardly from the engaging surface and into the cavity through an opening defined in the peripheral side wall and adjacent the floor of the cavity. The engaging surface and ramp are configured to secure at least part of the elongated delivery system externally of the cavity.

摘要翻译： 一种用于在非流体环境中存储人造瓣膜和细长递送系统的包装系统。 包装系统包括用于固定人造瓣膜和细长递送系统的托盘。 托盘包括尺寸和形状以容纳包含人造瓣膜的阀盖和细长递送系统的远端部分的至少一部分的腔体。 安装表面可拆卸地将阀盖连接到空腔底板并防止阀盖移动。 接合表面设置在腔的周边并且在空腔底板上方升高。 斜面从接合表面向下延伸并通过限定在周边侧壁中并邻近空腔底部的开口延伸到空腔中。 接合表面和斜面被构造成将至少部分细长的输送系统固定在空腔的外部。