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公开(公告)号：US20240033489A1
公开(公告)日：2024-02-01
申请号：US18379539
申请日：2023-10-12
发明人： Pu Zhou , Bin Tian , Yidong M. Zhu
IPC分类号： A61M25/10 , B23K26/362 , B23K26/402 , B23K26/0622 , B23K26/361 , B21D39/00 , B23K26/06
CPC分类号： A61M25/1029 , B23K26/362 , B23K26/402 , B23K26/0624 , B23K26/361 , B21D39/00 , B23K26/0626 , A61M2025/1031 , A61M2025/1086 , B23K2103/42
摘要： Inflatable devices are disclosed including a surface which has a network of polymer chains and is configured to be inflatable into a therapeutically or diagnostically useful shape, and at least one ultrashort laser pulse-formed modification in the surface. The network can, for example, include a network morphology that is substantially unchanged by modification with the ultrashort pulse laser. Ultrashort laser pulses can be laser pulses equal to or less than 1000 picoseconds in duration. Advantageously, the etching process uses a relatively low-heat laser to avoid significant heating of surrounding polymers while modifying the surface (and other structures) of the device. The process is configured so that the polymer chain morphology adjacent the modification is substantially unaffected by the low-heat laser. The resulting inflatable device has customized surface features while still retaining substantially homogenous polymer network morphology. This preserves the elasticity, especially the surface elasticity, of the inflatable device.
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公开(公告)号：US20230263629A1
公开(公告)日：2023-08-24
申请号：US18308498
申请日：2023-04-27
发明人： Yidong M. Zhu
CPC分类号： A61F2/2433 , A61M25/10184 , A61F2250/0003
摘要： The present embodiments relate generally to devices, systems, and methods for an inflatable device. A system may include an interior inflatable body configured to inflate in response to receiving fluid. The system may include an exterior inflatable body at least partially surrounding the interior inflatable body and configured to inflate when the interior inflatable body inflates and apply an expansion force to the surface to dilate the surface, the exterior inflatable body having a distal portion, a proximal portion, and one or more openings at the distal portion configured to allow the fluid within the interior inflatable body to escape the exterior inflatable body when the interior inflatable body is punctured or bursts.
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公开(公告)号：US11458015B2
公开(公告)日：2022-10-04
申请号：US16791976
申请日：2020-02-14
发明人： Yidong M. Zhu , Erik Bulman , Baigui Bian , Sam Sok , Pu Zhou
摘要： Disclosed herein are designs for improved inflatable structures for use during minimally invasive cardiovascular procedures. These inflatable structures facilitate the perfusion of blood through an anatomical structure, such as a heart valve, during the cardiovascular procedure. The inflatable structures are formed of a plurality of balloons arranged radially around a central location. The plurality of balloons form a lumen through which blood flows. Each balloon of the plurality is shaped or configured to stabilize the adjacent balloons, limiting their movement relative to each other. For example, some embodiments can feature balloons with a keystone shape that limits movement of the balloons inward toward the lumen. Some implementations can also include a support coil running through the lumen. The support coil holds enables the lumen to be open to perfusion even in the early stages of balloon inflation.
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公开(公告)号：US20200375736A1
公开(公告)日：2020-12-03
申请号：US16996776
申请日：2020-08-18
发明人： Yidong M. Zhu , Pu Zhou , Erik Bulman , Baigui Bian
摘要： The methods and devices disclosed herein promote temporal control of balloon inflation patterns. The devices include a covering for a portion of the balloon that compresses the balloon portion during the inflation process. This enables the distal portion of a balloon to be inflated prior to the proximal portion of a balloon, creating a tapered shape at lower inflation pressures. This is especially useful during transvascular implantation procedures, as it prevents dislodgement of an implant mounted on the balloon. As inflation continues, pressure exerted on the balloon by the covering is overcome such that the proximal region of the balloon inflates, forming a shape with generally straighter sides than the tapered shape, thereby expanding the cardiovascular device.
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公开(公告)号：US10751176B2
公开(公告)日：2020-08-25
申请号：US15248517
申请日：2016-08-26
发明人： Yidong M. Zhu , PU Zhou , Erik Bulman , Baigui Bian
摘要： The methods and devices disclosed herein promote temporal control of balloon inflation patterns. The devices include a covering for a portion of the balloon that compresses the balloon portion during the inflation process. This enables the distal portion of a balloon to be inflated prior to the proximal portion of a balloon, creating a tapered shape at lower inflation pressures. This is especially useful during transvascular implantation procedures, as it prevents dislodgement of an implant mounted on the balloon. As inflation continues, pressure exerted on the balloon by the covering is overcome such that the proximal region of the balloon inflates, forming a shape with generally straighter sides than the tapered shape, thereby expanding the cardiovascular device.
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公开(公告)号：US10391281B2
公开(公告)日：2019-08-27
申请号：US16149671
申请日：2018-10-02
发明人： Pu Zhou , Erik Bulman , Timothy A. Geiser , Michael G. Valdez , Yidong M. Zhu , Baigui Bian , Sonny Tran , Richard D. White , Thanh Huy Le , Tung T. Le , Alpana K. Gowdar , Yong Gao , David D. Williams
摘要： A delivery sheath includes an outer tubular layer and an initially folded inner tubular layer. When an implant passes therethrough, the outer tubular layer expands and the inner tubular layer unfolds into an expanded lumen diameter. The sheath may also include selectively placed longitudinal support rods that mediate friction between the inner and outer tubular layers to facilitate easy expansion, thereby reducing the push force needed to advance the implant through the sheath's lumen.
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公开(公告)号：US10391280B2
公开(公告)日：2019-08-27
申请号：US16149650
申请日：2018-10-02
发明人： Pu Zhou , Erik Bulman , Timothy A. Geiser , Michael G. Valdez , Yidong M. Zhu , Baigui Bian , Sonny Tran , Richard D. White , Thanh Huy Le , Tung T. Le , Alpana K. Gowdar , Yong Gao , David D. Williams
摘要： A delivery sheath includes an outer tubular layer and an initially folded inner tubular layer. When an implant passes therethrough, the outer tubular layer expands and the inner tubular layer unfolds into an expanded lumen diameter. The sheath may also include selectively placed longitudinal support rods that mediate friction between the inner and outer tubular layers to facilitate easy expansion, thereby reducing the push force needed to advance the implant through the sheath's lumen.
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公开(公告)号：US11547561B2
公开(公告)日：2023-01-10
申请号：US16996776
申请日：2020-08-18
发明人： Yidong M. Zhu , Pu Zhou , Erik Bulman , Baigui Bian
摘要： The methods and devices disclosed herein promote temporal control of balloon inflation patterns. The devices include a covering for a portion of the balloon that compresses the balloon portion during the inflation process. This enables the distal portion of a balloon to be inflated prior to the proximal portion of a balloon, creating a tapered shape at lower inflation pressures. This is especially useful during transvascular implantation procedures, as it prevents dislodgement of an implant mounted on the balloon. As inflation continues, pressure exerted on the balloon by the covering is overcome such that the proximal region of the balloon inflates, forming a shape with generally straighter sides than the tapered shape, thereby expanding the cardiovascular device.
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公开(公告)号：US11420026B2
公开(公告)日：2022-08-23
申请号：US16550922
申请日：2019-08-26
发明人： Pu Zhou , Erik Bulman , Timothy A. Geiser , Michael G. Valdez , Yidong M. Zhu , Baigui Bian , Sonny Tran , Richard D. White , Thanh Huy Le , Tung T. Le , Alpana Kiran Gowdar , Yong Gao , David Delon Williams
摘要： A delivery sheath includes an outer tubular layer and an initially folded inner tubular layer. When an implant passes therethrough, the outer tubular layer expands and the inner tubular layer unfolds into an expanded lumen diameter. The sheath may also include selectively placed longitudinal support rods that mediate friction between the inner and outer tubular layers to facilitate easy expansion, thereby reducing the push force needed to advance the implant through the sheath's lumen.
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公开(公告)号：US10561496B2
公开(公告)日：2020-02-18
申请号：US15260192
申请日：2016-09-08
发明人： Yidong M. Zhu , Erik Bulman , Baigui Bian , Sam Sok , Pu Zhou
摘要： Disclosed herein are designs for improved inflatable structures for use during minimally invasive cardiovascular procedures. These inflatable structures facilitate the perfusion of blood through an anatomical structure, such as a heart valve, during the cardiovascular procedure. The inflatable structures are formed of a plurality of balloons arranged radially around a central location. The plurality of balloons form a lumen through which blood flows. Each balloon of the plurality is shaped or configured to stabilize the adjacent balloons, limiting their movement relative to each other. For example, some embodiments can feature balloons with a keystone shape that limits movement of the balloons inward toward the lumen. Some implementations can also include a support coil running through the lumen. The support coil holds enables the lumen to be open to perfusion even in the early stages of balloon inflation.
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