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41.发明授权公开(公告)号：US10576135B2
公开(公告)日：2020-03-03
申请号：US16563151
申请日：2019-09-06
发明人： Toni Weinschenk , Jens Fritsche , Harpreet Singh , Andrea Mahr , Martina Ott , Claudia Wagner , Oliver Schoor
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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公开(公告)号：US10550167B2
公开(公告)日：2020-02-04
申请号：US16519987
申请日：2019-07-23
发明人： Andrea Mahr , Toni Weinschenk , Oliver Schoor , Jens Fritsche , Harpreet Singh , Claudia Wagner , Julia Leibold , Colette Song
IPC分类号： A61K35/17 , C07K14/47 , C07K14/725 , C07K14/74 , C12N5/0783 , C07K16/30 , C07K16/28 , A61P35/00 , G16B20/20 , G01N33/574 , C12Q1/6886 , A61K39/00
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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公开(公告)号：US10526389B2
公开(公告)日：2020-01-07
申请号：US16520003
申请日：2019-07-23
发明人： Andrea Mahr , Toni Weinschenk , Oliver Schoor , Jens Fritsche , Harpreet Singh , Claudia Wagner , Julia Leibold , Colette Song
IPC分类号： A61K39/00 , C07K14/47 , C07K14/725 , C07K14/74 , C12N5/0783 , A61K35/17 , C07K16/30 , C07K16/28 , A61P35/00 , G16B20/20 , G01N33/574 , C12Q1/6886
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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