公开(公告)号：US20050048104A1

公开(公告)日：2005-03-03

申请号：US10611531

申请日：2003-06-30

Applicant: Subramanian Venkatraman ,  Thomas Stein ,  James Snider ,  Richard Hamlin

Inventor： Subramanian Venkatraman ,  Thomas Stein ,  James Snider ,  Richard Hamlin

IPC: A61K9/70 ,  A61K31/138 ,  A61K31/216 ,  A61K31/4468 ,  A61K47/14 ,  A61K47/18 ,  A61K47/34 ,  A61P1/00 ,  A61P1/04 ,  A61P3/02 ,  A61P3/10 ,  A61P5/06 ,  A61P5/26 ,  A61P5/38 ,  A61P7/02 ,  A61P7/04 ,  A61P9/08 ,  A61P9/10 ,  A61P11/06 ,  A61P15/00 ,  A61P23/00 ,  A61P25/16 ,  A61P25/24 ,  A61P25/30 ,  A61P29/00 ,  A61P31/04 ,  A61P31/10 ,  A61P31/12 ,  A61P33/00 ,  A61P35/00 ,  A61P37/08 ,  A61P43/00 ,  C08G18/48 ,  C08G18/65 ,  C08G18/75 ,  C08K5/00 ,  C08L75/04

CPC classification number: A61K9/7069 ,  A61K9/7084 ,  A61K47/34

Abstract: The present invention relates to the field of transdermal drug delivery. More specifically, the present invention relates to drug reservoir materials for use in transdermal drug delivery devices. The drug reservoirs of the present invention comprise a polyurethane polymer which can be processed at temperatures below those which cause degradation of temperature sensitive drugs and/or excipients. The present invention is also directed to tailoring the release characteristics of the polyurethane material to accommodate a range of suitable drugs to be delivered from the transdermal drug delivery device and/or provide a range of delivery rates for a particular drug.

Abstract translation: 本发明涉及透皮药物递送领域。 更具体地，本发明涉及用于透皮药物递送装置的药物储存材料。 本发明的药物储存器包含聚氨酯聚合物，其可以在低于导致温度敏感性药物和/或赋形剂降解的温度下进行加工。 本发明还涉及定制聚氨酯材料的释放特性以适应从透皮药物递送装置递送的一定范围的合适药物和/或为特定药物提供一定范围的递送速率。