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公开(公告)号：US5746227A
公开(公告)日：1998-05-05
申请号：US483540
申请日：1995-06-07
Applicant: Jed E. Rose , Frederique Behm , James Turner
Inventor： Jed E. Rose , Frederique Behm , James Turner
CPC classification number: A61K9/007 , A24F47/002 , A61M11/001 , A61M15/00 , A61M15/0006 , A61M15/0028 , A61M15/0036 , A61M15/0041 , A61M15/06 , A61M2202/062 , A61M2202/064 , Y10T137/5196
Abstract: A method for delivering dry powder particles through the mouth of a user, in which a suction is created through an opening in a proximal end of an elongated housing for drawing air into a flow path in the housing from an opening in a distal end of the housing, the distal end including an opening in the housing with a ridge surrounding the housing, and through a resistance member in the housing for introducing a controlled pressure drop in the housing and a resistance to the drawing of air into the mouth of the user. A measured amount of dry powder particles having a therapeutic capability, is introduced into the housing so that the particles will travel downstream from the resistance member at a relatively low velocity in a non-agglomerated state, the dry powder particles being sized and coordinated with the controlled pressure drop so that the particles can be drawn into the mouth of the user and inhaled, with the resistance being sufficiently great that the particles are drawn into the mouth of the user to simulate the action of puffing on a cigarette so that at least some of the particles are deposited in the oral cavity and upper respiratory tract of the user after being drawn into the mouth.
Abstract translation: 一种用于将干燥粉末颗粒输送通过使用者口腔的方法，其中通过细长壳体的近端中的开口产生吸力，用于从空腔的远端中的开口将空气吸入壳体中的流动路径 所述远端包括在所述壳体中的开口，所述开口具有围绕所述壳体的脊，并且通过所述壳体中的阻力构件，用于在所述壳体中引入受控的压降并且阻止将空气抽吸到所述使用者的口中。 将测量量的具有治疗能力的干粉颗粒引入壳体中，使得颗粒将以非聚集状态的相对较低的速度从阻力构件下游移动，干粉颗粒的尺寸和配合与 控制的压降使得颗粒可以被吸入使用者的嘴中并被吸入，其阻力足够大，使得颗粒被吸入使用者的口中以模拟在香烟上膨化的作用，使得至少一些 的颗粒在吸入口腔后沉积在使用者的口腔和上呼吸道中。
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公开(公告)号：US5687746A
公开(公告)日：1997-11-18
申请号：US477562
申请日：1995-06-07
Applicant: Jed E. Rose , Frederique Behm , James Turner
Inventor： Jed E. Rose , Frederique Behm , James Turner
CPC classification number: A61K9/007 , A24F47/002 , A61M11/001 , A61M15/00 , A61M15/0006 , A61M15/0028 , A61M15/0036 , A61M15/0041 , A61M15/06 , A61M2202/062 , A61M2202/064 , Y10T137/5196
Abstract: A dry powder delivery system having an elongated tube containing a matrix having a measured mount of dry particles of therapeutic compound and a porous element having a desiccant therein is disclosed. The porous element with the desiccant can be combined with the powder-containing matrix or it can be two separate elements. The pressure drop induced by inhalation of the user causes air to flow through the tube and into contact with the particles of dry powder for discharging the particles for inhalation by the user.
Abstract translation: 公开了一种干粉输送系统，其具有包含具有测量的治疗化合物的干颗粒的基质的基质的细长管和其中具有干燥剂的多孔元件。 具有干燥剂的多孔元件可以与含粉末的基质组合，或者它可以是两个分开的元素。 吸入使用者引起的压降导致空气流过管并与干粉颗粒接触，用于排出用户吸入的颗粒。
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公开(公告)号：US4294155A
公开(公告)日：1981-10-13
申请号：US112895
申请日：1980-01-17
Applicant: James Turner
Inventor： James Turner
Abstract: An electronic musical keyboard instrument that is controlled by a digital processor. Key and stops/effects statuses are sampled, during successive time intervals, and read into random access memory associated with the digital processor. After manipulation and/or supplementation of the status information to effect implementation of various features, key-representative signals are read out to tone generation and voicing circuits.
Abstract translation: 由数字处理器控制的电子音乐键盘乐器。 键和停止/效果状态在连续的时间间隔期间进行采样，并读入与数字处理器相关联的随机存取存储器。 在操作和/或补充状态信息以实现各种特征之后，将键代表信号读出到音调生成和发声电路。
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