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公开(公告)号:US20160145246A1
公开(公告)日:2016-05-26
申请号:US14747394
申请日:2015-06-23
IPC分类号: C07D413/12 , C07D403/12 , C07D401/10 , C07D249/08
CPC分类号: A61K31/4196 , A61K31/454 , A61K31/497 , A61K31/5377 , A61K45/06 , C07D249/08 , C07D401/10 , C07D401/12 , C07D403/12 , C07D413/12 , Y02A50/465
摘要: The present invention relates to compounds of formula I: and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising the compounds of formula I, and methods of using said compounds, salts and compositions in the treatment of various disorders associated with CRM1 activity.
摘要翻译: 本发明涉及式I化合物及其药学上可接受的盐,包含式I化合物的药物组合物,以及使用所述化合物,盐和组合物治疗与CRM1活性相关的各种疾病的方法。