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公开(公告)号:US20100129930A1
公开(公告)日:2010-05-27
申请号:US12309728
申请日:2007-07-27
申请人: Roberto Polakewicz , Charles Farnsworth , Ailan Guo , Klarisa Rikova , Albrecht Moritz , Kimberly Lee , Erik Spek
发明人: Roberto Polakewicz , Charles Farnsworth , Ailan Guo , Klarisa Rikova , Albrecht Moritz , Kimberly Lee , Erik Spek
CPC分类号: C07K16/44 , C07K16/30 , G01N33/573 , G01N33/574 , G01N33/6842
摘要: The invention discloses 351 novel phosphorylation sites identified in carcinoma, peptides (including AQUA peptides) comprising a phosphorylation site of the invention, antibodies specifically bind to a novel phosphorylation site of the invention, and diagnostic and therapeutic uses of the above.
摘要翻译: 本发明公开了在癌中鉴定的351个新的磷酸化位点,包含本发明的磷酸化位点的肽(包括AQUA肽),特异性结合本发明的新的磷酸化位点的抗体,以及上述的诊断和治疗用途。
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公开(公告)号:US20100129929A1
公开(公告)日:2010-05-27
申请号:US12309727
申请日:2007-07-27
申请人: Roberto Polakewicz , Charles Farnsworth , Ailan Guo , Klarisa Rikova , Albrecht Moritz , Kimberly Lee , Erik Spek
发明人: Roberto Polakewicz , Charles Farnsworth , Ailan Guo , Klarisa Rikova , Albrecht Moritz , Kimberly Lee , Erik Spek
CPC分类号: C07K16/44
摘要: The invention discloses 349 novel phosphorylation sites identified in carcinoma, peptides (including AQUA peptides) comprising a phosphorylation site of the invention, antibodies specifically bind to a novel phosphorylation site of the invention, and diagnostic and therapeutic uses of the above.
摘要翻译: 本发明公开了在癌中鉴定的349个新的磷酸化位点,包含本发明的磷酸化位点的肽(包括AQUA肽),特异性结合本发明的新的磷酸化位点的抗体,以及上述的诊断和治疗用途。
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公开(公告)号:US20100216718A1
公开(公告)日:2010-08-26
申请号:US12738524
申请日:2008-10-20
申请人: Klarisa Rikova
发明人: Klarisa Rikova
IPC分类号: A61K38/16 , G01N33/574 , A61P35/00
CPC分类号: G01N33/57423 , A61K31/506 , C12Q1/485 , C12Q1/6886 , C12Q2600/112 , C12Q2600/158 , G01N33/57415 , G01N33/5743 , G01N33/57434 , G01N33/57446 , G01N33/57492 , G01N2333/91205 , G01N2800/52 , G01N2800/7028
摘要: The present invention relates to methods of classifying cancer cells based on the presence, absence or level of a tyrosine kinase or a phosphorylated tyrosine kinase. The present invention also relates to methods of treating cancer using cancer classification. The present invention further relates to methods of determining the effectiveness of a treatment for cancer using cancer classification.
摘要翻译: 本发明涉及基于酪氨酸激酶或磷酸化酪氨酸激酶的存在,不存在或水平对癌细胞进行分类的方法。 本发明还涉及使用癌症分类治疗癌症的方法。 本发明还涉及使用癌症分类来确定癌症治疗的有效性的方法。
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