公开(公告)号：US20060229701A1

公开(公告)日：2006-10-12

申请号：US11372932

申请日：2006-03-10

申请人： Hitinder Gurm ,  Jay Yadav ,  Ji-Feng Chen

发明人： Hitinder Gurm ,  Jay Yadav ,  Ji-Feng Chen

IPC分类号： A61F2/06

CPC分类号： A61F2/958

摘要： An apparatus for use with an expandable stent having oppositely disposed first and second terminal edges. The apparatus has a catheter shaft with a lumen, and an inflatable balloon with oppositely disposed first and second end portions and an internal chamber. The internal chamber is in fluid communication with the lumen of the catheter shaft, and receives inflation fluid to inflate the balloon. The balloon has cylindrical inner and outer surfaces that extend between the end portions. The cylindrical inner surface is secured to the catheter shaft at first and second attachment sites adjacent the first and second end portions, respectively. At least one of the first and second end portions of the balloon has a toroidal shape defined by an arcuate end surface that intersects the cylindrical inner and outer surfaces at a common radial plane. A respective one of the attachment sites is located adjacent the one end portion lying adjacent the common radial plane. The balloon is positionable within the stent so that one of the terminal edges of the stent lies in the common radial plane to ensure that, when the balloon is expanded, the one terminal edge receives full and uniform expansion pressure.

摘要翻译： 一种与具有相对设置的第一和第二端边缘的可扩张支架一起使用的装置。 该装置具有带内腔的导管轴和具有相对设置的第一和第二端部和内部腔室的可膨胀气囊。 内室与导管轴的内腔流体连通，并接收充气流体以使气囊膨胀。 气球具有在端部之间延伸的圆柱形内表面和外表面。 圆柱形内表面分别在与第一和第二端部相邻的第一和第二附接位置处固定到导管轴。 球囊的第一和第二端部中的至少一个具有由弧形端面限定的环形形状，该圆弧端面与圆柱形内表面和外表面在共同的径向平面相交。 附接位置中的相应一个位于邻近公共径向平面的一个端部附近。 气囊可以定位在支架内，使得支架的一个端部边缘位于共同的径向平面中，以确保当气囊膨胀时，一个末端边缘接收完全均匀的膨胀压力。

公开(公告)号：US20060195060A1

公开(公告)日：2006-08-31

申请号：US11325816

申请日：2006-01-05

申请人： Jose Navia ,  Jose Navia ,  Jorge Jordana ,  Ji-Feng Chen

发明人： Jose Navia ,  Jose Navia ,  Jorge Jordana ,  Ji-Feng Chen

IPC分类号： A61M29/00

CPC分类号： A61M1/3653 ,  A61F2/01 ,  A61F2/90 ,  A61F2220/0008 ,  A61M1/3613 ,  A61M1/3659

摘要： An apparatus and method for automatically retroperfusing a coronary vein. The apparatus includes an intraluminal graft having a tubular body extending between a proximal end and a distal end. The proximal end is for fluidly connecting to an artery to automatically supply retrograde blood for retroperfusion. The tubular body and the distal end are extendable into a vein that is fluidly connected with the coronary vein to be retroperfused. The distal end includes an expandable stent for securing the distal end in the coronary vein.

公开(公告)号：US06534004B2

公开(公告)日：2003-03-18

申请号：US09752313

申请日：2000-12-28

申请人： Ji-Feng Chen ,  Kent Wika

发明人： Ji-Feng Chen ,  Kent Wika

IPC分类号： B01J1900

CPC分类号： A61L27/3691 ,  A01N1/00 ,  A01N1/02 ,  A01N1/0221 ,  A61L2/0094 ,  A61L2/08 ,  A61L2/20 ,  A61L2/206 ,  A61L27/36 ,  A61L27/3683 ,  A61L2202/21

摘要： A method that allows for dry storage of bioprosthetic devices comprising a tissue component is provided. The method comprises the steps of providing a device comprising a chemically cross-linked animal tissue component; treating the tissue component with an aqueous solution comprising a biocompatible, water soluble, organic molecule comprising a plurality of carbon atoms and a plurality of hydroxyl groups for a time sufficient to allow equilibration between the fluids in the interstices of the tissue component and the aqueous solution; and then sterilizing the treated tissue component using a sterilizing gas or ionizing radiation. The present invention also relates to an implantable tissue component that can be stored dry. The tissue component is chemically-fixed and comprises within the interstices thereof a dimensional stabilizer selected from the group consisting of a polyhydric alcohol and derivatives thereof, a water soluble carbohydrate, and a water soluble gum. The tissue component is disposed within the chamber of a package, the chamber being defined by one or more members formed from a material that is resistant to penetration by micro-organisms, particularly bacteria and fungi. The chamber and tissue component are sterile and essentially free of an aldehyde solution. Except for the liquids contained within the tissue component, the chamber is also essentially free of liquid.

摘要翻译： 提供允许包含组织成分的生物假体装置的干燥储存的方法。 该方法包括提供包括化学交联动物组织成分的装置的步骤; 用含有包含多个碳原子和多个羟基的生物相容的水溶性有机分子的水溶液处理组织成分足以允许组织组分和水溶液间隙中的流体之间的平衡的时间 ; 然后使用灭菌气体或电离辐射对经处理的组织组分进行灭菌。 本发明还涉及可以干燥储存的可植入组织成分。 组织组分是化学固定的，并且在其间隙内包含选自多元醇及其衍生物，水溶性碳水化合物和水溶性胶质的尺寸稳定剂。 组织部件设置在包装的腔室内，该腔室由一种或多种由能够被微生物特别是细菌和真菌穿透的材料形成的构件限定。 腔室和组织组分是无菌的，基本上不含醛溶液。 除了包含在组织部件内的液体之外，室也基本上没有液体。