专利检索 ap:("Rajashehar Betageri" OR "Steffen Breitfelder" OR "Pier F. Cirillo" OR "Thomas A. Gilmore" OR "Eugene R. Hickey" OR "Thomas M. Kirrane" OR "Monica H. Moriak" OR "Neil Moss" OR "Usha R. Patel" OR "John R. Proudfoot" OR "John R. Regan" OR "Rajiv Sharma" OR "Sanxing Sun" OR "Alan D. Swinamer" OR "Hidenori Takahashi") AND inv:"Steffen Breitfelder" 第 5 页

41.

发明授权
Esters of hydroxyl-substituted nitrogen heterocycles, processes for the preparation thereof as well as the use thereof as pharmaceutical compositions 有权
标题翻译：羟基取代的氮杂环的酯，其制备方法及其作为药物组合物的用途

公开(公告)号：US07094788B2

公开(公告)日：2006-08-22

申请号：US10396147

申请日：2003-03-25

申请人： Matthias Grauert , Michael P. Pieper , Gerald Pohl , Georg Speck , Steffen Breitfelder

发明人： Matthias Grauert , Michael P. Pieper , Gerald Pohl , Georg Speck , Steffen Breitfelder

IPC分类号： C07D31/403 , C07D221/22 , C07D471/08 , C07D471/10 , C07D409/10

CPC分类号： C07D451/02 , A61K31/46 , A61K45/06

摘要： The present invention relates to new compounds of general formula 1 wherein X− and the groups A, B, R, R1, R2, R3, R3′, R4, R4′, Rx and Rx′ may have the meanings given in the claims and in the specification, processes for preparing them and their use as pharmaceutical compositions.

摘要翻译： 本发明涉及通式1的新化合物，其中X，O和A，B，R，R 1，R 2， R 3，R 3，R 4，R 4，R 4，R 12， >和R“X”可以具有权利要求书和说明书中给出的含义，其制备方法及其作为药物组合物的用途。

42.

发明申请
Esters of hydroxyl-substituted nitrogen heterocycles, processes for the preparation thereof as well as the use thereof as pharmaceutical compositions 有权
标题翻译：羟基取代的氮杂环的酯，其制备方法及其作为药物组合物的用途

公开(公告)号：US20060058344A1

公开(公告)日：2006-03-16

申请号：US11270303

申请日：2005-11-09

申请人： Matthias Grauert , Michael Pieper , Gerald Pohl , Georg Speck , Steffen Breitfelder

发明人： Matthias Grauert , Michael Pieper , Gerald Pohl , Georg Speck , Steffen Breitfelder

IPC分类号： A61K31/46

CPC分类号： C07D451/02 , A61K31/46 , A61K45/06

摘要： The present invention relates to new compounds of general formula 1 wherein X− and the groups A, B, R, R1, R2, R3, R3′, R4, R4′, Rx and Rx′ may have the meanings given in the claims and in the specification, processes for preparing them and their use as pharmaceutical compositions.

摘要翻译： 本发明涉及通式1的新化合物

43.

发明申请
Intermediate compounds for making dihydropteridinones useful as pharmaceutical compositions 审中-公开
标题翻译：用作制备二氢蝶啶酮的中间体化合物，可用作药物组合物

公开(公告)号：US20050014761A1

公开(公告)日：2005-01-20

申请号：US10909008

申请日：2004-07-30

申请人： Matthias Hoffmann , Matthias Grauert , Trixi Brandl , Steffen Breitfelder , Christian Eickmeier , Martin Steegmaier , Gisela Schnapp , Anke Baum , Jens Quant , Flavio Solca , Florian Colbatzky

发明人： Matthias Hoffmann , Matthias Grauert , Trixi Brandl , Steffen Breitfelder , Christian Eickmeier , Martin Steegmaier , Gisela Schnapp , Anke Baum , Jens Quant , Flavio Solca , Florian Colbatzky

IPC分类号： A61P35/00 , C07D475/00 , C07D519/00 , A61K31/525 , C07D475/02

CPC分类号： C07D295/073 , C07D475/00

摘要： Disclosed are new dihydropteridinones of general formula (I) wherein the groups L and R1-R5 have the meanings given in the claims and specification, the isomers thereof, intermediates and processes for preparing these dihydropteridinones and the use thereof as pharmaceutical compositions.

摘要翻译： 公开了通式（I）的新的二氢蝶啶酮，其中基团L和R 1 -R 5具有权利要求书和说明书中给出的含义，其异构体，制备这些二氢蝶呤的中间体和方法及其用途药物组合物。