公开(公告)号：US12209095B2

公开(公告)日：2025-01-28

申请号：US17620255

申请日：2020-11-20

Applicant: LG CHEM, LTD.

Inventor： Kyunghee Kim ,  Wanpyo Hong ,  Sujeong Geum ,  Moung Gon Kim ,  Yonghan Lee

IPC: C07D491/22 ,  C07C15/28 ,  C07D307/91 ,  C07D333/08 ,  C07D333/76 ,  C07D405/10 ,  C07D405/14 ,  C07D409/10 ,  C07D409/14 ,  C07D487/06 ,  C07D487/16 ,  C07D491/16 ,  C07D495/16 ,  C07D495/22 ,  C07F7/08 ,  H10K50/125 ,  H10K85/40 ,  H10K85/60

Abstract: Provided is a compound of Formula 1: wherein: X and Y are independently O, S, or CZ1Z2; Ring A is a benzene or naphthalene ring; A1 to A4 are independently hydrogen, deuterium, a halogen group, a cyano group, a nitro group, a hydroxyl group, or a substituted or unsubstituted: alkyl, cycloalkyl, aryl, or heterocyclic group; R1 to R6, Z1, and Z2 are independently a substituted or unsubstituted: alkyl, aryl, or heterocyclic group; n1 to n3, m, and l are 0 or 1 and n1+n2+n3 is ≥2; a1 and a2 are 1 to 4; a3 is 1 to 3; a4 is 1 to 6; and when a1 to a4 are each 2 or higher, structures in the parenthesis are the same or different, provided that when Ring A is naphthalene, m is 0, and when l is 1, Ring A is a benzene ring, and an organic light-emitting device comprising the compound.

公开(公告)号：US20240315130A1

公开(公告)日：2024-09-19

申请号：US18276297

申请日：2022-02-24

Applicant: LT MATERIALS CO., LTD.

Inventor： Nam Jin LEE ,  Dong Jin LEE ,  Won Jang JEONG ,  Dong Jun KIM

IPC: H10K85/60 ,  C07D219/08 ,  C07D405/10 ,  C07D405/12 ,  C07D409/04 ,  C07D409/10 ,  C07D409/12 ,  C09K11/06 ,  H10K50/11 ,  H10K50/15 ,  H10K50/18

CPC classification number: H10K85/636 ,  C07D219/08 ,  C07D405/10 ,  C07D405/12 ,  C07D409/04 ,  C07D409/10 ,  C07D409/12 ,  C09K11/06 ,  H10K85/633 ,  C09K2211/1018 ,  H10K50/11 ,  H10K50/15 ,  H10K50/181 ,  H10K85/615 ,  H10K85/622 ,  H10K85/626 ,  H10K85/6572 ,  H10K85/6574 ,  H10K85/6576

Abstract: The present disclosure relates to a heterocyclic compound represented by Chemical Formula 1, an organic light emitting device comprising the same, a manufacturing method thereof, and a composition for organic material layer.

公开(公告)号：US20240298534A1

公开(公告)日：2024-09-05

申请号：US18618426

申请日：2024-03-27

Applicant: Universal Display Corporation

Inventor： Lichang ZENG ,  Suman LAYEK ,  Pennington T. BOUDREAULT ,  Zeinab ELSHENAWY ,  Gregg KOTTAS ,  Alexey Borisovich DYATKIN ,  Scott JOSEPH ,  Vadim ADAMOVICH ,  Chuanjun XIA ,  Ting-Chih WANG ,  Walter YEAGER

IPC: H10K85/60 ,  C07D251/24 ,  C07D405/10 ,  C07D409/04 ,  C07D409/10 ,  C07D421/10 ,  C09K11/02 ,  C09K11/06 ,  H10K50/11 ,  H10K50/16 ,  H10K85/30 ,  H10K101/10

CPC classification number: H10K85/654 ,  C07D251/24 ,  C07D405/10 ,  C07D409/04 ,  C07D409/10 ,  C07D421/10 ,  C09K11/025 ,  C09K11/06 ,  H10K85/342 ,  H10K85/626 ,  H10K85/6574 ,  H10K85/6576 ,  C09K2211/1007 ,  C09K2211/1059 ,  C09K2211/1092 ,  C09K2211/1096 ,  C09K2211/185 ,  H10K50/11 ,  H10K50/16 ,  H10K2101/10

Abstract: A composition of materials including a first compound having a structure according to Formula I

公开(公告)号：US20240277852A1

公开(公告)日：2024-08-22

申请号：US18559655

申请日：2022-05-19

Applicant: DANA-FARBER CANCER INSTITUTE, INC. ,  CORNELL UNIVERSITY

Inventor： Nathanael S. Gray ,  Mingxing Teng ,  Eric Wang ,  Jie Jiang ,  Tinghu Zhang ,  Lewis C. Cantley ,  Eric S. Fischer ,  Katherine A. Donovan

IPC: A61K47/55 ,  A61K31/505 ,  A61K31/506 ,  A61K31/5383 ,  A61K47/54 ,  C07D239/42 ,  C07D401/04 ,  C07D401/10 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C07D409/04 ,  C07D409/10 ,  C07D417/04 ,  C07D498/14

CPC classification number: A61K47/55 ,  A61K31/505 ,  A61K31/506 ,  A61K31/5383 ,  A61K47/545 ,  C07D239/42 ,  C07D401/04 ,  C07D401/10 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C07D409/04 ,  C07D409/10 ,  C07D417/04 ,  C07D498/14

Abstract: The present invention relates to compounds, compositions, and methods for treating diseases or conditions by modulating (e.g., reducing) the level or activity of at least one of PIP4K2A, PIP4K2B, and PIP4K2C.

公开(公告)号：US12063851B2

公开(公告)日：2024-08-13

申请号：US16030689

申请日：2018-07-09

Applicant: IDEMITSU KOSAN CO., LTD.

Inventor： Tomoki Kato ,  Nobuhiro Yabunouchi ,  Takahiro Fujiyama

IPC: H10K85/60 ,  C07D405/04 ,  C07D405/10 ,  C07D405/14 ,  C07D409/10 ,  C07D409/14 ,  C07D457/04 ,  C07D487/04 ,  C07D491/048 ,  C07D495/04 ,  C09B57/00 ,  C09B69/00 ,  C09K11/06 ,  H05B33/20 ,  H10K50/11 ,  H10K85/30

CPC classification number: H10K85/615 ,  C07D405/10 ,  C07D405/14 ,  C07D457/04 ,  C07D487/04 ,  C07D491/048 ,  C07D495/04 ,  C09B57/00 ,  C09B69/008 ,  C09K11/06 ,  H05B33/20 ,  H10K85/657 ,  H10K85/6572 ,  H10K85/6574 ,  C09K2211/1007 ,  C09K2211/1029 ,  C09K2211/1033 ,  C09K2211/1044 ,  C09K2211/1059 ,  C09K2211/1092 ,  C09K2211/185 ,  H10K50/11 ,  H10K85/342 ,  H10K85/631

Abstract: A nitrogen-containing aromatic heterocyclic derivative in which a nitrogen atom of an indenocarbazole skeleton optionally having a hetero atom or an indenoindole skeleton optionally having a hetero atom is bonded to a dibenzofuran or a dibenzothiophene directly or indirectly. The derivative realizes an organic EL device with a high emission efficiency and a long lifetime.

公开(公告)号：US12060331B2

公开(公告)日：2024-08-13

申请号：US16960980

申请日：2019-01-04

Applicant: SYNGENTA PARTICIPATIONS AG

Inventor： Kenneth Bruce Ling ,  Christopher John Mathews ,  Timothy Jeremiah Cornelius O'Riordan ,  Stephen Edward Shanahan ,  Joseph Andrew Tate ,  Christiana Kitsiou ,  Peter Timothy Seden

IPC: C07D237/04 ,  A01N43/58 ,  A01N43/78 ,  C07D237/16 ,  C07D401/10 ,  C07D403/10 ,  C07D409/10 ,  C07D417/10

CPC classification number: C07D237/04 ,  A01N43/58 ,  A01N43/78 ,  C07D237/16 ,  C07D401/10 ,  C07D403/10 ,  C07D409/10 ,  C07D417/10

Abstract: The present invention relates to herbicidal substituted phenyl-pyridazine-diones and substituted phenyl-pyridazinone derivatives of formula (I), as well as to processes and intermediates used for the preparation of such derivatives. The invention further extends to herbicidal compositions comprising such derivatives, as well as to the use of such compounds and compositions in controlling undesirable plant growth: in particular the use in controlling weeds, such as broad-leaved dicotyledonous weeds, in crops of useful plants.

公开(公告)号：US12053473B2

公开(公告)日：2024-08-06

申请号：US17077232

申请日：2020-10-22

Applicant: Boehringer Ingelheim International GmbH

Inventor： Dirk Kessler ,  Christiane Kofink ,  Matthew Russell Netherton ,  Juergen Ramharter ,  Tobias Wunberg

IPC: A61K31/517 ,  A61K9/20 ,  A61K31/337 ,  A61K31/496 ,  A61K31/506 ,  A61K31/519 ,  A61K31/5377 ,  A61K31/7068 ,  A61P35/00 ,  C07D239/94 ,  C07D401/14 ,  C07D403/10 ,  C07D405/12 ,  C07D405/14 ,  C07D409/10 ,  C07D413/10 ,  C07D487/04

CPC classification number: A61K31/517 ,  A61K9/2009 ,  A61K9/2018 ,  A61K9/2027 ,  A61K9/2054 ,  A61K9/2059 ,  A61K31/337 ,  A61K31/496 ,  A61K31/506 ,  A61K31/519 ,  A61K31/5377 ,  A61K31/7068 ,  A61P35/00 ,  C07D239/94 ,  C07D401/14 ,  C07D403/10 ,  C07D405/12 ,  C07D405/14 ,  C07D409/10 ,  C07D413/10 ,  C07D487/04

Abstract: The present invention encompasses compounds of formula (I)




wherein the groups R1 to R7 have the meanings given in the claims and specification, their use as inhibitors of SOS1, pharmaceutical compositions which contain compounds of this kind and their use as medicaments/medical uses, especially as agents for treatment and/or prevention of oncological diseases.

公开(公告)号：US20240254099A1

公开(公告)日：2024-08-01

申请号：US18289138

申请日：2022-04-08

Applicant: LT MATERIALS CO., LTD.

Inventor： Ji Un KIM ,  GWANG IL DONG ,  Yong Hui LEE ,  Won Jang JEONG ,  Dong Jun KIM

IPC: C07D333/76 ,  C07B59/00 ,  C07D409/10 ,  C07D409/12 ,  H10K50/15 ,  H10K50/16 ,  H10K85/60

CPC classification number: C07D333/76 ,  C07B59/004 ,  C07D409/10 ,  C07D409/12 ,  H10K50/15 ,  H10K50/16 ,  H10K85/615 ,  H10K85/633 ,  H10K85/6574 ,  H10K85/6576 ,  C07B2200/05

Abstract: The present disclosure relates to a heterocyclic compound represented by Chemical Formula 1 and an organic light emitting device comprising the same.

公开(公告)号：US20240254079A1

公开(公告)日：2024-08-01

申请号：US18239892

申请日：2023-08-30

Applicant: ARCUS BIOSCIENCES, INC.

Inventor： Joel Worley BEATTY ,  Samuel Lawrie DREW ,  Matthew EPPLIN ,  Jeremy Thomas Andre FOURNIER ,  Balint GAL ,  Tezcan GUNEY ,  Karl T. HAELSIG ,  Clayton HARDMAN ,  Steven Donald JACOB ,  Jenna Leigh JEFFREY ,  Jaroslaw KALISIAK ,  Kenneth Victor LAWSON ,  Manmohan Reddy LELETI ,  Erick Allen LINDSEY ,  Artur Karenovich MAILYAN ,  Debashis MANDAL ,  Guillaume MATA ,  Hyunyoung MOON ,  Jay Patrick POWERS ,  Brandon Reid ROSEN ,  Yongli SU ,  Anh Thu TRAN ,  Zhang WANG ,  Xuelei YAN ,  Kai YU

IPC: C07C317/32 ,  A61K31/10 ,  A61K31/277 ,  A61K31/343 ,  A61K31/353 ,  A61K31/365 ,  A61K31/381 ,  A61K31/404 ,  A61K31/415 ,  A61K31/416 ,  A61K31/4174 ,  A61K31/4192 ,  A61K31/4196 ,  A61K31/421 ,  A61K31/423 ,  A61K31/426 ,  A61K31/428 ,  A61K31/437 ,  A61K31/44 ,  A61K31/4412 ,  A61K31/47 ,  A61K31/4709 ,  A61K31/472 ,  A61K31/4965 ,  A61K31/50 ,  A61K31/5025 ,  A61K31/505 ,  A61K31/519 ,  A61K31/538 ,  A61K39/395 ,  A61K45/06 ,  C07C255/53 ,  C07C317/22 ,  C07C317/36 ,  C07D209/34 ,  C07D211/86 ,  C07D213/57 ,  C07D213/71 ,  C07D213/73 ,  C07D213/74 ,  C07D213/84 ,  C07D215/48 ,  C07D217/04 ,  C07D231/12 ,  C07D231/56 ,  C07D233/64 ,  C07D237/20 ,  C07D239/42 ,  C07D241/12 ,  C07D249/06 ,  C07D249/08 ,  C07D263/32 ,  C07D263/57 ,  C07D265/36 ,  C07D277/30 ,  C07D277/56 ,  C07D277/64 ,  C07D307/83 ,  C07D311/22 ,  C07D333/64 ,  C07D401/04 ,  C07D401/10 ,  C07D409/10 ,  C07D413/10 ,  C07D471/04 ,  C07D487/04

CPC classification number: C07C317/32 ,  A61K31/10 ,  A61K31/277 ,  A61K31/343 ,  A61K31/353 ,  A61K31/365 ,  A61K31/381 ,  A61K31/404 ,  A61K31/415 ,  A61K31/416 ,  A61K31/4174 ,  A61K31/4192 ,  A61K31/4196 ,  A61K31/421 ,  A61K31/423 ,  A61K31/426 ,  A61K31/428 ,  A61K31/437 ,  A61K31/44 ,  A61K31/4412 ,  A61K31/47 ,  A61K31/4709 ,  A61K31/472 ,  A61K31/4965 ,  A61K31/50 ,  A61K31/5025 ,  A61K31/505 ,  A61K31/519 ,  A61K31/538 ,  A61K39/3955 ,  A61K45/06 ,  C07C255/53 ,  C07C317/22 ,  C07C317/36 ,  C07D209/34 ,  C07D211/86 ,  C07D213/57 ,  C07D213/71 ,  C07D213/73 ,  C07D213/74 ,  C07D213/84 ,  C07D215/48 ,  C07D217/04 ,  C07D231/12 ,  C07D231/56 ,  C07D233/64 ,  C07D237/20 ,  C07D239/42 ,  C07D241/12 ,  C07D249/06 ,  C07D249/08 ,  C07D263/32 ,  C07D263/57 ,  C07D265/36 ,  C07D277/30 ,  C07D277/56 ,  C07D277/64 ,  C07D307/83 ,  C07D311/22 ,  C07D333/64 ,  C07D401/04 ,  C07D401/10 ,  C07D409/10 ,  C07D413/10 ,  C07D471/04 ,  C07D487/04 ,  C07C2602/08 ,  C07C2602/10

Abstract: Compounds that inhibit HIF-2α, and compositions containing the compound(s) and methods for synthesizing the compounds, are described herein. Also described are the use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by HIF-2α.

公开(公告)号：US20240251665A1

公开(公告)日：2024-07-25

申请号：US18285084

申请日：2022-03-31

Applicant: TOSOH CORPORATION

Inventor： Masaya HIRANO ,  Naoki MATSUMOTO ,  Hirokazu SHINYA ,  Shintaro NOMURA ,  Hiroyuki KAWASHIMA ,  Kenji KOIKE

IPC: H10K85/60 ,  C07D209/88 ,  C07D405/04 ,  C07D405/10 ,  C07D405/12 ,  C07D405/14 ,  C07D409/04 ,  C07D409/10 ,  C07D409/12 ,  C07D409/14 ,  C09K11/06 ,  H10K50/15 ,  H10K50/17 ,  H10K85/40

CPC classification number: H10K85/636 ,  C07D209/88 ,  C07D405/04 ,  C07D405/10 ,  C07D405/12 ,  C07D405/14 ,  C07D409/04 ,  C07D409/10 ,  C07D409/12 ,  C07D409/14 ,  C09K11/06 ,  H10K85/40 ,  H10K85/633 ,  C09K2211/1018 ,  H10K50/15 ,  H10K50/17 ,  H10K85/615 ,  H10K85/622 ,  H10K85/624 ,  H10K85/626 ,  H10K85/6572 ,  H10K85/6574 ,  H10K85/6576

Abstract: There is provided a transverse current suppressing material that suppresses a transverse current of an organic electroluminescent element, a carbazole compound, a hole-injection layer containing the transverse current suppressing material and the carbazole compound and an organic electroluminescent element that has good drive voltage, luminous efficiency and durability and has a lower transverse current. A transverse current suppressing material for an organic electroluminescent element, represented by the formula (1) [In the formula (1), A is represented by the formula (2) or (3), and B is represented by the formula (4)].