公开(公告)号：US06547994B1

公开(公告)日：2003-04-15

申请号：US09439179

申请日：1999-11-12

申请人： Donald C. Monkhouse ,  Sandeep Kumar ,  Charles W. Rowe ,  Jaedeok Yoo

发明人： Donald C. Monkhouse ,  Sandeep Kumar ,  Charles W. Rowe ,  Jaedeok Yoo

IPC分类号： B29C4102

CPC分类号： B29C64/165 ,  B29L2031/753 ,  B33Y80/00

摘要： A fabrication method to rapidly fabricate different prototypes of drug delivery systems, medical devices, pharmaceutical dosage forms, tissue scaffolds or other bioaffecting agents in small batches or individual forms using a computer-guided system to vary the composition and structure in order to optimize the product and the manufacturing process. The process is immediately scalable. An Expert System can be used with the method to recommend different compositions and designs of the prototypes, devices, dosage forms, tissue scaffold or other bioaffecting agents.

摘要翻译： 使用计算机引导系统以小批量或单独形式快速制造药物递送系统，医疗装置，药物剂型，组织支架或其它生物影响剂的不同原型的制造方法，以改变组合物和结构以优化产品 和制造过程。 该过程可以立即升级。 专家系统可以用于推荐原型，装置，剂型，组织支架或其它生物影响剂的不同成分和设计的方法。

公开(公告)号：US06470339B1

公开(公告)日：2002-10-22

申请号：US09281876

申请日：1999-03-31

申请人： Alan H. Karp ,  Rajiv Gupta ,  Arindam Banerji ,  Chia-Chiang Chao ,  Ernest Mak ,  Sandeep Kumar ,  Venkatesh Krishnan ,  Guillermo Rozas

发明人： Alan H. Karp ,  Rajiv Gupta ,  Arindam Banerji ,  Chia-Chiang Chao ,  Ernest Mak ,  Sandeep Kumar ,  Venkatesh Krishnan ,  Guillermo Rozas

IPC分类号： G06F1700

CPC分类号： G06F9/468 ,  Y10S707/99938 ,  Y10S707/99939

摘要： A software system that provides access control to resources and that disassociates access rights to resources from references to resources to prevent the formation of large and unwieldy access control lists and to enable advanced decentralized security controls. The software system includes a repository that holds a resource descriptor for each resource including lock/permission pairs. Access to particular resources or groups of resources is provided by providing users with the appropriate keys. The keys are themselves are resources with resource descriptors in the repository. Access rights for users may be revoked by deleting keys from the repository. The software system also provides visibility fields for compartmentalizing access to resources. In addition, the software system provides authorizers that maintain audit trails when critical resource such as keys are passed among users and that enable advanced security control when passing resources among users.

摘要翻译： 一种提供对资源的访问控制以及将资源的访问权限从资源引用分解的软件系统，以防止形成大而笨重的访问控制列表并实现高级分散安全控制。 该软件系统包括一个存储库，其中包含包含锁/权限对的每个资源的资源描述符。 通过向用户提供适当的密钥来提供对特定资源或资源组的访问。 密钥本身就是存储库中资源描述符的资源。 可以通过从存储库中删除密钥来撤消对用户的访问权限。 软件系统还提供可视化领域，用于区分对资源的访问。 此外，软件系统提供授权人员，当关键资源（如密钥在用户中传递）之间时，可以维护审计跟踪，并且在用户之间传递资源时可实现高级安全控制。

公开(公告)号：US20210232312A1

公开(公告)日：2021-07-29

申请号：US17214534

申请日：2021-03-26

申请人： Aravinda Prasad ,  Sandeep Kumar ,  Sreenivas Subramoney ,  Andy Rudoff

发明人： Aravinda Prasad ,  Sandeep Kumar ,  Sreenivas Subramoney ,  Andy Rudoff

IPC分类号： G06F3/06

摘要： Disclosed Methods, Apparatus, and articles of manufacture to profile page tables for memory management are disclosed. An example apparatus includes a processor to execute computer readable instructions to: profile a first page at a first level of a page table as not part of a target group; and in response to profiling the first page as not part of the target group, label a data page at a second level that corresponds to the first page as not part of the target group, the second level being lower than the first level.

公开(公告)号：US10688013B2

公开(公告)日：2020-06-23

申请号：US16440943

申请日：2019-06-13

申请人： Debbie Joles ,  Chad Morgan ,  Sandeep Kumar

发明人： Debbie Joles ,  Chad Morgan ,  Sandeep Kumar

IPC分类号： A61H3/04 ,  A61H3/00

摘要： Disclosed herein are novel embodiments of progressive mobility aid devices. Such progressive mobility aid devices are designed to progress through a variety of configurations to accommodate the use of the progressive mobility aid device in a safe and secure manner as the user of the progressive mobility aid device traverses a variety of surfaces and terrain such as traversing irregular surfaces including sidewalks and stone-based surfaces; loose surfaces and terrain including gravel and sand; soft surfaces including wet ground and carpeted surfaces; and variable gradient surfaces including stairs and inclining or declining surfaces and terrain. The progressive mobility aid devices accommodate such uses with an articulating design that provides for front legs of the progressive mobility aid device to be pivotably adjusted with respect to the rear legs of the progressive mobility aid device, and with wheel assemblies that are selectively deployable and retractable.

公开(公告)号：US20180169238A1

公开(公告)日：2018-06-21

申请号：US15795135

申请日：2017-10-26

申请人： Mark White ,  Sandeep Kumar ,  Christopher Chan ,  Spencer Liang ,  Lance Stapleton ,  Andrew W. Drake ,  Yosi Gozlan ,  Ilan Vaknin ,  Shirley Sameah-Greenwald ,  Liat Dassa ,  Zohar Tiran ,  Gad S. Cojocaru ,  Maya Kotturi ,  Hsin-Yuan Cheng ,  Kyle Hansen ,  David Nisim Giladi ,  Einav Safyon ,  Eran Ophir ,  Leonard Presta ,  Richard Theolis ,  Radhika Desai ,  Patrick Wall

发明人： Mark White ,  Sandeep Kumar ,  Christopher Chan ,  Spencer Liang ,  Lance Stapleton ,  Andrew W. Drake ,  Yosi Gozlan ,  Ilan Vaknin ,  Shirley Sameah-Greenwald ,  Liat Dassa ,  Zohar Tiran ,  Gad S. Cojocaru ,  Maya Kotturi ,  Hsin-Yuan Cheng ,  Kyle Hansen ,  David Nisim Giladi ,  Einav Safyon ,  Eran Ophir ,  Leonard Presta ,  Richard Theolis ,  Radhika Desai ,  Patrick Wall

IPC分类号： A61K39/395

CPC分类号： C07K16/2809 ,  A61K39/39541 ,  A61K39/39558 ,  A61K2039/505 ,  A61K2039/507 ,  A61K2039/572 ,  A61P35/00 ,  C07K16/2803 ,  C07K16/2818 ,  C07K16/2827 ,  C07K2317/21 ,  C07K2317/24 ,  C07K2317/33 ,  C07K2317/34 ,  C07K2317/522 ,  C07K2317/524 ,  C07K2317/526 ,  C07K2317/53 ,  C07K2317/55 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/622 ,  C07K2317/732 ,  C07K2317/76 ,  C07K2317/92 ,  C07K2317/94 ,  C07K2319/035 ,  C07K2319/33

摘要： Anti-PVRIG and anti-TIGIT antibodies are provided.

公开(公告)号：US09752154B2

公开(公告)日：2017-09-05

申请号：US14416799

申请日：2013-07-23

申请人： DOW AGROSCIENCES LLC ,  Sandeep Kumar ,  Steven L. Evans ,  Manju Gupta

发明人： Sandeep Kumar ,  Steven L. Evans ,  Manju Gupta

IPC分类号： C12N15/68 ,  C12N15/82

CPC分类号： C12N15/8209 ,  C12N15/68 ,  C12N15/82

摘要： This invention is related to methods and systems for vector assembly for transgenic plants. A uniform modular process is used to reduce cycle time and the methods and systems provided herein can increase cloning throughput using multiple-well plates, for example 96-well plates. In some embodiments, the methods and systems provided herein eliminate or reduce the need for sequencing confirmation because no PCR is involved in the vector assembly process.

公开(公告)号：US09688996B2

公开(公告)日：2017-06-27

申请号：US14416811

申请日：2013-08-08

申请人： DOW AGROSCIENCES LLC ,  Sandeep Kumar ,  Manju Gupta ,  Diaa Alabed

发明人： Sandeep Kumar ,  Manju Gupta ,  Diaa Alabed

IPC分类号： C12N15/82

CPC分类号： C12N15/8216 ,  C12N15/8218

摘要： Provided are methods, vectors and gene constructs for enhancing expression of a recombinant nucleic acid sequence in transgenic plants and plant tissues. According to the present invention, nucleic acid sequences are obtained and/or derived from the 3′ untranslated regions of genes encoding ubiquitin proteins and engineered to flank respective portions of a selected coding region of a vector. The vector construct may be introduced into plants and/or plant tissues through conventional or gene targeting procedures, resulting in enhanced expression of the selected coding region. In some embodiments, the selected coding region is a chimeric gene or gene fragment expressing one or more proteins known to impart a level of insecticidal activity to a transgenic plant and/or plant tissue.

公开(公告)号：US09114072B2

公开(公告)日：2015-08-25

申请号：US13369473

申请日：2012-02-09

申请人： Jaedeok Yoo ,  Sandeep Kumar ,  Donald C. Monkhouse

发明人： Jaedeok Yoo ,  Sandeep Kumar ,  Donald C. Monkhouse

IPC分类号： A61K9/00 ,  A61K9/14 ,  A61F13/15 ,  B27N3/00 ,  B32B17/00 ,  B29D11/00 ,  B29C35/04 ,  A61K9/20

CPC分类号： A61K9/0056 ,  A61K9/2072 ,  A61K9/2095 ,  B33Y80/00

摘要： A rapidly dispersing dosage form is described, which releases its active ingredients within a period of less than about ninety seconds. These dosage forms exhibit a three-dimensional shape that is retained for adequate storage but is readily dispersed in the presence of excess moisture. Also disclosed are methods of administration of a medicament and a process for the preparation of rapidly dispersing dosage forms.

公开(公告)号：US08745179B2

公开(公告)日：2014-06-03

申请号：US11669799

申请日：2007-01-31

申请人： Kollivakkam Raghavan ,  Sandeep Kumar

发明人： Kollivakkam Raghavan ,  Sandeep Kumar

IPC分类号： G06F15/177 ,  G06F15/173 ,  H04L12/24

CPC分类号： H04L41/0806 ,  H04L41/0803 ,  H04L41/0813 ,  H04L41/0816 ,  H04L41/0853 ,  H04L41/0856 ,  H04L67/26 ,  H04L67/34

摘要： A system that enables automatic version provisioning in heterogeneous application oriented network (AON) architectures is provided. Generally, the specification enables appropriate version configurations to be selected at runtime as needed in an AON environment. More particularly, the subject specification describes the ability of a device (e.g., AON node) to perform and/or select a self-configuration operation based upon the environment and the runtime operation. To facilitate message-based runtime instantiation of the appropriate configuration, the system enables network applicable configurations to be pushed to each of the nodes in the AON architecture.

摘要翻译： 提供了一种在异构面向应用的网络（AON）体系结构中实现自动版本配置的系统。 通常，规范允许在运行时根据需要在AON环境中选择适当的版本配置。 更具体地，主题说明书描述了设备（例如，AON节点）基于环境和运行时操作执行和/或选择自配置操作的能力。 为了促进基于消息的运行时实例化适当的配置，系统使网络适用的配置被推送到AON架构中的每个节点。

公开(公告)号：US08386507B2

公开(公告)日：2013-02-26

申请号：US13105746

申请日：2011-05-11

申请人： Rajiv Puranik ,  Jay Ramamurthi ,  ChyrSong Ting ,  Scott Haynie ,  Timothy R. McCune ,  Sandeep Kumar

发明人： Rajiv Puranik ,  Jay Ramamurthi ,  ChyrSong Ting ,  Scott Haynie ,  Timothy R. McCune ,  Sandeep Kumar

IPC分类号： G06F17/30

CPC分类号： G06F17/30902

摘要： A method and apparatus for intelligent caching is provided. A thin layer of business logic on a web server receives URL requests sent to the web server from clients and resolves the URLs into URLs corresponding to component parts of the requested document according to the rules of a rule set. Thus only the component resources of a composite document are cached in the web server's caching layer. The rule set defines a format for the requests sent to the web server, the manner in which properly formatted requests should be resolved, and the manner in which the component resources should be assembled into the composite document.

摘要翻译： 提供了智能缓存的方法和装置。 Web服务器上的一薄层业务逻辑接收从客户端发送到Web服务器的URL请求，并根据规则集的规则将URL解析为对应于所请求文档的组成部分的URL。 因此，只有复合文档的组件资源被缓存在Web服务器的缓存层中。 规则集定义了发送到Web服务器的请求的格式，应解析格式正确的请求的方式以及将组件资源组装到复合文档中的方式。