公开(公告)号：US07850839B2

公开(公告)日：2010-12-14

申请号：US11378944

申请日：2006-03-16

申请人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Yoshinobu Tokuno ,  Kazuhiro Matsumoto ,  Yasuhiko Sawada

发明人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Yoshinobu Tokuno ,  Kazuhiro Matsumoto ,  Yasuhiko Sawada

IPC分类号： G01N27/327

CPC分类号： G01N27/327 ,  A61B5/1486 ,  A61B2562/0295 ,  C12Q1/001 ,  C12Q1/005 ,  C12Q1/006 ,  G01N27/26 ,  G01N27/3272 ,  G01N27/3274 ,  G01N33/48771 ,  G01N33/5438

摘要： A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes via the connecting terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.

摘要翻译： 提供了测量样品液体中所含的基板的量的方法。 该方法可以减少由生物传感器引起的测量误差。 生物传感器至少包括绝缘板上的一对电极，插入到测量装置中，该测量装置包括用于可拆卸地支撑生物传感器的支撑部分，要耦合到各个电极的多个连接端子和施加一个电极的驱动电源 通过连接端子对各个电极施加电压。 只有当生物传感器沿给定的方向插入到测量装置中时，生物传感器的电极中的一个连接到测量装置的第一和第二连接端子，并且具有这样的结构，使得电极在第一和第二 由驱动电源施加电压引起的连接端子。

公开(公告)号：US07232510B2

公开(公告)日：2007-06-19

申请号：US10182236

申请日：2001-11-30

申请人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Yoshinobu Tokuno ,  Kazuhiro Matsumoto ,  Yasuhiko Sawada

发明人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Yoshinobu Tokuno ,  Kazuhiro Matsumoto ,  Yasuhiko Sawada

IPC分类号： G01N27/327

CPC分类号： G01N27/327 ,  A61B5/1486 ,  A61B2562/0295 ,  C12Q1/001 ,  C12Q1/005 ,  C12Q1/006 ,  G01N27/26 ,  G01N27/3272 ,  G01N27/3274 ,  G01N33/48771 ,  G01N33/5438

摘要： A biosensor, a measuring instrument for biosensor, and a method of quantifying a substrate contained in specimen liquid to reduce a measurement error by the biosensor; a biosensor, comprising at least a pair of electrodes formed on an insulation substrate; a measuring instrument, comprising a supporting part for detachably supporting the biosensor, a plurality of connection terminals electrically connected to the electrodes, and a drive power supply for applying a voltage to the electrodes through the connection terminals; wherein the biosensor is inserted into the measuring instrument, either one of the electrodes of the biosensor is connected to first and second connection terminals fined to the measuring instrument only when the biosensor is inserted into the support part of the measuring instrument in a specified direction and has an electrode structure to allow the first connection terminal to conduct with the second connection terminal when a voltage is applied by the drive power supply.

摘要翻译： 生物传感器，生物传感器用测定装置以及检测用液体中含有的基板的量化方法，以减少生物传感器的测定误差。 生物传感器，包括形成在绝缘基板上的至少一对电极; 测量仪器，包括用于可拆卸地支撑生物传感器的支撑部件，电连接到电极的多个连接端子，以及通过连接端子向电极施加电压的驱动电源; 其中生物传感器被插入到测量仪器中，只有当生物传感器沿着指定的方向插入到测量仪器的支撑部分中时，生物传感器的电极中的任一个连接到精细到测量仪器的第一和第二连接端子，并且 具有电极结构，以在由驱动电源施加电压时允许第一连接端子与第二连接端子导通。

公开(公告)号：US06881322B2

公开(公告)日：2005-04-19

申请号：US09937300

申请日：2001-01-25

申请人： Hiroyuki Tokunaga ,  Shoji Miyazaki

发明人： Hiroyuki Tokunaga ,  Shoji Miyazaki

IPC分类号： G01N27/327 ,  G01N33/487

CPC分类号： G01N27/3273

摘要： A reaction layer 12 which reacts with a substance to be measured in a sample solution is provided on a working electrode 1, a counter electrode 2, and a third electrode 3 which are provided on an insulating substrate 7 so as to bridge the respective electrodes, the content of the substance to be measured is measured from a current value which reaction is obtained between the working electrode 1 and the counter electrode 2, and the types of sample solution is judged by a difference between oxidation current values or between oxidation current waveforms, which are obtained between the third electrode 3 and the counter electrode 2 or between the third electrode 3 and the working electrode 1, thereby automatically judging the types of sample solution.

摘要翻译： 将反应层12与样品溶液中的待测物质反应，设置在工作电极1，对电极2和第三电极3上，工作电极1，对电极2和第三电极3设置在绝缘基板7上以桥接各个电极， 根据从工作电极1和对电极2之间获得的反应的电流值来测量待测物质的含量，并且通过氧化电流值或氧化电流波形之间的差来判断样品溶液的种类， 其在第三电极3和对电极2之间或第三电极3和工作电极1之间获得，从而自动判断样品溶液的类型。

公开(公告)号：US20140144791A1

公开(公告)日：2014-05-29

申请号：US14166956

申请日：2014-01-29

申请人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Yoshinobu Tokuno

发明人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Yoshinobu Tokuno

IPC分类号： G01N27/327

CPC分类号： G01N27/327 ,  A61B5/1486 ,  A61B2562/0295 ,  C12Q1/001 ,  C12Q1/005 ,  C12Q1/006 ,  G01N27/26 ,  G01N27/3272 ,  G01N27/3274 ,  G01N33/48771 ,  G01N33/5438

摘要： A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltages to the respective electrodes via the connecting terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.

摘要翻译： 提供了测量样品液体中所含的基板的量的方法。 该方法可以减少由生物传感器引起的测量误差。 生物传感器至少包括绝缘板上的一对电极，插入到测量装置中，该测量装置包括用于可拆卸地支撑生物传感器的支撑部分，要耦合到各个电极的多个连接端子和施加一个电极的驱动电源 通过连接端子对各个电极施加电压。 只有当生物传感器沿给定方向插入到测量装置中时，生物传感器的电极之一才连接到测量装置的第一和第二连接端子，并且具有使得电极在第一和第二连接之间变得导电的结构 由于驱动电源施加的电压引起的端子。

公开(公告)号：US20120043227A1

公开(公告)日：2012-02-23

申请号：US13317662

申请日：2011-10-25

申请人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Yoshinobu Tokuno ,  Kazuhiro Matsumoto ,  Yasuhiko Sawada

发明人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Yoshinobu Tokuno ,  Kazuhiro Matsumoto ,  Yasuhiko Sawada

IPC分类号： G01N27/327

CPC分类号： G01N27/327 ,  A61B5/1486 ,  A61B2562/0295 ,  C12Q1/001 ,  C12Q1/005 ,  C12Q1/006 ,  G01N27/26 ,  G01N27/3272 ,  G01N27/3274 ,  G01N33/48771 ,  G01N33/5438

摘要： A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes via the connecting terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.

公开(公告)号：US20110132776A1

公开(公告)日：2011-06-09

申请号：US12931296

申请日：2011-01-28

申请人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Yoshinobu Tokuno

发明人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Yoshinobu Tokuno

IPC分类号： G01N27/327 ,  G01N33/50

CPC分类号： G01N27/327 ,  A61B5/1486 ,  A61B2562/0295 ,  C12Q1/001 ,  C12Q1/005 ,  C12Q1/006 ,  G01N27/26 ,  G01N27/3272 ,  G01N27/3274 ,  G01N33/48771 ,  G01N33/5438

摘要： A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes via the connecting terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.

公开(公告)号：US20100252454A1

公开(公告)日：2010-10-07

申请号：US12802608

申请日：2010-06-10

申请人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Yoshinobu Tokuno ,  Kazuhiro Matsumoto ,  Yasuhiko Sawada

发明人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Yoshinobu Tokuno ,  Kazuhiro Matsumoto ,  Yasuhiko Sawada

IPC分类号： G01N27/403

CPC分类号： G01N27/327 ,  A61B5/1486 ,  A61B2562/0295 ,  C12Q1/001 ,  C12Q1/005 ,  C12Q1/006 ,  G01N27/26 ,  G01N27/3272 ,  G01N27/3274 ,  G01N33/48771 ,  G01N33/5438

摘要： A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes via the connecting terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.

公开(公告)号：US20130020208A1

公开(公告)日：2013-01-24

申请号：US13609305

申请日：2012-09-11

申请人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Yoshinobu Tokuno ,  Kazuhiro Matsumoto ,  Yasuhiko Sawada

发明人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Yoshinobu Tokuno ,  Kazuhiro Matsumoto ,  Yasuhiko Sawada

IPC分类号： G01N27/327

CPC分类号： G01N27/327 ,  A61B5/1486 ,  A61B2562/0295 ,  C12Q1/001 ,  C12Q1/005 ,  C12Q1/006 ,  G01N27/26 ,  G01N27/3272 ,  G01N27/3274 ,  G01N33/48771 ,  G01N33/5438

摘要： A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes via the connecting terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.

摘要翻译： 提供了测量样品液体中所含的基板的量的方法。 该方法可以减少由生物传感器引起的测量误差。 生物传感器至少包括绝缘板上的一对电极，插入到测量装置中，该测量装置包括用于可拆卸地支撑生物传感器的支撑部分，要耦合到各个电极的多个连接端子和施加一个电极的驱动电源 通过连接端子对各个电极施加电压。 只有当生物传感器沿给定的方向插入到测量装置中时，生物传感器的电极中的一个连接到测量装置的第一和第二连接端子，并且具有这样的结构，使得电极在第一和第二 由驱动电源施加电压引起的连接端子。

公开(公告)号：US20100320097A1

公开(公告)日：2010-12-23

申请号：US12803253

申请日：2010-06-22

申请人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Yoshinobu Tokuno ,  Kazuhiro Matsumoto ,  Yasuhiko Sawada

发明人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Yoshinobu Tokuno ,  Kazuhiro Matsumoto ,  Yasuhiko Sawada

IPC分类号： G01N27/26 ,  G01K1/00

CPC分类号： G01N27/327 ,  A61B5/1486 ,  A61B2562/0295 ,  C12Q1/001 ,  C12Q1/005 ,  C12Q1/006 ,  G01N27/26 ,  G01N27/3272 ,  G01N27/3274 ,  G01N33/48771 ,  G01N33/5438

摘要： A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes via the connecting terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.

摘要翻译： 提供了测量样品液体中所含的基板的量的方法。 该方法可以减少由生物传感器引起的测量误差。 生物传感器至少包括绝缘板上的一对电极，插入到测量装置中，该测量装置包括用于可拆卸地支撑生物传感器的支撑部分，要耦合到各个电极的多个连接端子和施加一个电极的驱动电源 通过连接端子对各个电极施加电压。 只有当生物传感器沿给定的方向插入到测量装置中时，生物传感器的电极中的一个连接到测量装置的第一和第二连接端子，并且具有这样的结构，使得电极在第一和第二 由驱动电源施加电压引起的连接端子。

公开(公告)号：US20080110754A1

公开(公告)日：2008-05-15

申请号：US11800273

申请日：2007-05-03

申请人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Yoshinobu Tokuno ,  Kazuhiro Matsumoto ,  Yasuhiko Sawada

发明人： Shoji Miyazaki ,  Hiroyuki Tokunaga ,  Yoshinobu Tokuno ,  Kazuhiro Matsumoto ,  Yasuhiko Sawada

IPC分类号： G01N27/26

CPC分类号： G01N27/327 ,  A61B5/1486 ,  A61B2562/0295 ,  C12Q1/001 ,  C12Q1/005 ,  C12Q1/006 ,  G01N27/26 ,  G01N27/3272 ,  G01N27/3274 ,  G01N33/48771 ,  G01N33/5438

摘要： A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes via the connecting terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.

摘要翻译： 提供了测量样品液体中所含的基板的量的方法。 该方法可以减少由生物传感器引起的测量误差。 生物传感器至少包括绝缘板上的一对电极，插入到测量装置中，该测量装置包括用于可拆卸地支撑生物传感器的支撑部分，要耦合到各个电极的多个连接端子和施加一个电极的驱动电源 通过连接端子对各个电极施加电压。 只有当生物传感器沿给定的方向插入到测量装置中时，生物传感器的电极中的一个连接到测量装置的第一和第二连接端子，并且具有这样的结构，使得电极在第一和第二 由驱动电源施加电压引起的连接端子。