TARGETING VEGF-B REGULATION OF FATTY ACID TRANSPORTERS TO MODULATE HUMAN DISEASES
    51.
    发明申请
    TARGETING VEGF-B REGULATION OF FATTY ACID TRANSPORTERS TO MODULATE HUMAN DISEASES 有权
    针对脂肪酸转运蛋白调控人类疾病的VEGF-B调控

    公开(公告)号:US20120114642A1

    公开(公告)日:2012-05-10

    申请号:US13343493

    申请日:2012-01-04

    申请人: ULF ERIKSSON

    发明人: ULF ERIKSSON

    摘要: The present invention provides materials and methods for modulating FATP expression and/or activity in vivo. The materials and methods have numerous diagnostic, prophylactic, and therapeutic applications for various diseases and conditions that are influenced by FATPs, or characterized by excessive or inadequate FATP expression or activity.

    摘要翻译: 本发明提供了用于在体内调节FATP表达和/或活性的材料和方法。 这些材料和方法对于受FATP影响的各种疾病和病症具有许多诊断,预防和治疗应用,或者由于过度或不足的FATP表达或活性。

    Targeting VEGF-B regulation of fatty acid transporters to modulate human diseases
    53.
    发明授权
    Targeting VEGF-B regulation of fatty acid transporters to modulate human diseases 有权
    靶向脂肪酸转运蛋白的VEGF-B调节调节人类疾病

    公开(公告)号:US08114399B2

    公开(公告)日:2012-02-14

    申请号:US12299672

    申请日:2007-05-17

    申请人: Ulf Eriksson

    发明人: Ulf Eriksson

    摘要: The present invention provides materials and methods for modulating FATP expression and/or activity in vivo. The materials and methods have numerous diagnostic, prophylactic, and therapeutic applications for various diseases and conditions that are influenced by FATPs, or characterized by excessive or inadequate FATP expression or activity.

    摘要翻译: 本发明提供了用于在体内调节FATP表达和/或活性的材料和方法。 这些材料和方法对于受FATP影响的各种疾病和病症具有许多诊断,预防和治疗应用,或者由于过度或不足的FATP表达或活性。

    Cleaning device, cleaning tool and method of using the cleaning device
    54.
    发明授权
    Cleaning device, cleaning tool and method of using the cleaning device 失效
    清洁装置,清洁工具以及使用清洁装置的方法

    公开(公告)号:US07971539B2

    公开(公告)日:2011-07-05

    申请号:US10962534

    申请日:2004-10-13

    IPC分类号: F23G7/04

    CPC分类号: D21C11/106

    摘要: A cleaning device, cleaning tool and method for cleaning outlet ports or the like and/or outlet spouts (12) or the like in soda recovery boilers of the like the cleaning device including at least one connecting rod and at least one front tool part mounted on the connecting rod.

    摘要翻译: 清洁装置,清洁工具以及用于清洁诸如此类的苏打水回收锅炉中的出口等的出口和/或出口(12)等的方法,该清洁装置包括至少一个连接杆和至少一个前部工具部件 在连杆上。

    Steering wheel adjusting mechanism for motor vehicles
    55.
    发明授权
    Steering wheel adjusting mechanism for motor vehicles 有权
    机动车辆方向盘调整机构

    公开(公告)号:US07866698B2

    公开(公告)日:2011-01-11

    申请号:US11793758

    申请日:2005-12-16

    申请人: Ulf Eriksson

    发明人: Ulf Eriksson

    IPC分类号: B62D1/18

    CPC分类号: B62D1/184

    摘要: The invention relates to a steering wheel adjusting mechanism (2) for motor vehicles (4) comprising a pivotally to the vehicle (4) attached supporting arm (8), and a pivotally to the supporting arm (8) attached steering shaft housing unit (12), where at least one locking plate package (14 and 16, respectively) is attached to both the vehicle (4) and the steering shaft housing unit (12), which locking plate package (14 and 16, respectively) is compressible with clamping means (18) in order to lock the steering shaft housing unit (12) relative to the vehicle (4). Optionally, the supporting arm (8) is pivotally attached to a to the vehicle (4) mountable fastening part (20). Optionally, the locking plate package (14 and 16, respectively) is attached to a firmly to the vehicle (4) mountable fastening unit (22). Optionally, the fastening part (20) and the fastening unit (22) are integrated with each other to a firmly to the vehicle (4) mountable steering wheel adjusting bracket (24).

    摘要翻译: 本发明涉及一种用于机动车辆(4)的方向盘调节机构(2),其包括枢转地连接到车辆(4)附接的支撑臂(8),并且枢转地连接到支撑臂(8),转向轴壳体单元 12),其中至少一个锁定板封装(分别为14和16)分别连接到车辆(4)和转向轴壳体单元(12)上,该锁定板封装(14和16)分别可压缩 夹紧装置(18),以便相对于车辆(4)锁定转向轴壳体单元(12)。 可选地,支撑臂(8)可枢转地附接到车辆(4)可安装紧固部分(20)。 可选地,锁定板封装(14和16分别)被牢固地附接到车辆(4)可安装紧固单元(22)。 可选地,紧固部件(20)和紧固单元(22)彼此一体地牢固地固定到车辆(4)可安装的方向盘调节支架(24)上。

    TELESCOPIC SHAFT
    56.
    发明申请
    TELESCOPIC SHAFT 有权
    TELESCOPIC轴

    公开(公告)号:US20100130293A1

    公开(公告)日:2010-05-27

    申请号:US12601702

    申请日:2008-05-28

    IPC分类号: F16D3/06

    摘要: The invention relates to a telescopic shaft for vehicles comprising an inner shaft (14) axially movable in an outer shaft (16), where the telescopic shaft (4) comprises at least two rows (35, 37) of balls (36, 38) with at least one ball (36, 38) a row (35, 37) between the inner shaft (14) and the outer shaft (16), where a row (35) of balls (36) is arranged on at least one ball race (40) arranged against the inner shaft (14), where the ball race (40) is wedge shaped on its against the inner shaft (14) facing surface and that the telescopic shaft (4) comprises a prestress mechanism (46) which pushes the ball race (40) along a wedge unit (48) axially in relation to and radially in the direction against the outer shaft (16) whereby the telescopic shaft (48) is prestressed and that the prestress mechanism (46) is arranged to release the prestress when the alteration in length of the telescopic shaft (4) exceeds a predetermined length.

    摘要翻译: 本发明涉及一种用于车辆的伸缩轴,包括可在外轴(16)中可轴向移动的内轴(14),其中伸缩轴(4)包括至少两排(35,37)的球(36,38) 在内轴(14)和外轴(16)之间具有至少一个球(36,38)一排(35,37),其中一排(35)的球(36)布置在至少一个球 (40)抵靠所述内轴(14)布置,其中所述球座(40)在其抵靠所述内轴(14)面向表面上是楔形的,并且所述伸缩轴(4)包括预应力机构(46),所述预应力机构 沿着楔形单元(48)沿相对于径向方向相对于外轴(16)的方向推动球座(40),由此伸缩轴(48)被预应力,并且预应力机构(46)被布置成 当伸缩轴(4)的长度变化超过预定长度时,释放预应力。

    Steering Wheel Arrangement
    58.
    发明申请
    Steering Wheel Arrangement 有权
    方向盘布置

    公开(公告)号:US20090173180A1

    公开(公告)日:2009-07-09

    申请号:US12091755

    申请日:2005-10-28

    IPC分类号: B62D1/184 B62D1/189

    摘要: A steering wheel arrangement for a motor vehicle includes a steering column having a first end for cooperation with a steering wheel and a second end for cooperation with a vehicle steering mechanism. The steering wheel arrangement further includes a suspension arrangement for the steering column. The suspension arrangement includes two pivot joints and is pivotally connected to the steering column via a third pivot joint, the first, second and third pivot joints including first, second and third locking arrangements, respectively. The steering wheel arrangement has thus three adjustable pivot points where only one or two of the three pivot joints are adjustable in a first step depressing a foot pedal to a first position and only the remaining of the three pivot joints are adjustable in a second step depressing the foot pedal to a second position which implies that the adjustments can be made in a secure way by the driver during the ride.

    摘要翻译: 用于机动车辆的方向盘装置包括转向柱,其具有用于与方向盘配合的第一端和用于与车辆转向机构配合的第二端。 方向盘装置还包括用于转向柱的悬挂装置。 悬挂装置包括两个枢转接头,并经由第三枢转接头枢转地连接到转向柱,第一,第二和第三枢转接头分别包括第一,第二和第三锁定装置。 因此,方向盘装置具有三个可调枢轴点,其中三个枢轴接头中只有一个或两个在第一步骤中可调节,第一步骤将脚踏板压下到第一位置,并且只有剩余的三个枢转接头在第二阶段压下 脚踏板到第二位置,这意味着驾驶员可以在驾驶期间以安全的方式进行调节。

    Method for modulating, regulating and/or stabilizing angiogenesis
    59.
    发明授权
    Method for modulating, regulating and/or stabilizing angiogenesis 失效
    调节,调节和/或稳定血管发生的方法

    公开(公告)号:US07476654B2

    公开(公告)日:2009-01-13

    申请号:US11073605

    申请日:2005-03-08

    IPC分类号: A61K38/18

    CPC分类号: A61K38/1858 A61K48/00

    摘要: A method of modulating, regulating and/or stabilizing angiogenesis in a mammal in need thereof, in which the PDGF-D level or activity or both in the mammal are modulated or increased. In preferred embodiments, an active PDGF-D polypeptide, or a polynucleotide encoding an active PDGF-D is administered to the mammal, preferably at a location where angiogenesis modulation or stabilization is desired. The PDGF-D is advantageously co-administered with an angiogenic growth factor, such as a member of the VEGF family of growth factors, in particular VEGF-E. The claimed method inhibits leakage of blood vessels and is useful, inter alia, for treatment of edemas.

    摘要翻译: 在有需要的哺乳动物中调节,调节和/或稳定血管发生的方法,其中调节或增加哺乳动物的PDGF-D水平或活性。 在优选的实施方案中,将活性PDGF-D多肽或编码活性PDGF-D的多核苷酸施用于哺乳动物,优选在需要血管生成调节或稳定的位置。 PDGF-D有利地与血管生成生长因子如生长因子VEGF家族的成员,特别是VEGF-E共同施用。 所要求保护的方法抑制血管渗漏,尤其用于治疗水肿。