公开(公告)号：US20230051890A1

公开(公告)日：2023-02-16

申请号：US17978826

申请日：2022-11-01

Applicant: Edwards Lifesciences Corporation

Inventor： Noam Nir ,  Michael Bukin

IPC: A61F2/24

Abstract: A buckle commissure clamp can be used to attach leaflets of a valvular structure to a frame of a prosthetic heart valve. Tabs of adjacent leaflets can be assembled to the buckle commissure clamp by passing each leaflet through one or more gaps of the buckle commissure clamp. Each leaflet tab can be wrapped around portions of the buckle commissure clamp. Once the leaflet tabs are assembled to the buckle commissure clamp, the assembly can be attached to the frame, for example, by one or more sutures extending between the buckle commissure clamp and a support member, such as a strut of the frame, an actuator of the frame, a locking mechanism of the frame. In some embodiments, the buckle commissure clamp has a substantially W-shape or M-shape.

公开(公告)号：US20220409366A1

公开(公告)日：2022-12-29

申请号：US17901602

申请日：2022-09-01

Applicant: Edwards Lifesciences Corporation

Inventor： Michael Bukin ,  Noam Nir ,  Tamir S. Levi ,  Ziv Yohanan ,  Elena Sherman ,  Eran Goldberg ,  David Maimon

IPC: A61F2/24

Abstract: A prosthetic heart valve and associated methods for assembling a prosthetic heart valve including a plurality of leaflets is disclosed. As one example, a prosthetic heart valve includes a frame; a plurality of commissure support elements, each connected the frame and including two axially-extending members spaced apart from one another to form a window; and a plurality of leaflets, each leaflet comprising a body and two opposing commissure tabs, each commissure tab arranged adjacent to another commissure tab to form a pair of commissure tabs that are disposed in a commissure support element to form a commissure. Each commissure tab includes a series of overlapping layers that include a first set of two overlapping layers that extends through the window and a second set of two overlapping layers that extends away from the first set of two overlapping layers and over an outer side of a corresponding axially-extending member.

公开(公告)号：US20220387175A1

公开(公告)日：2022-12-08

申请号：US17889309

申请日：2022-08-16

Applicant: Edwards Lifesciences Corporation

Inventor： Ziv Yohanan ,  Noam Nir ,  Elena Sherman

IPC: A61F2/24

Abstract: A prosthetic heart valve comprises an annular frame that is radially compressible and expandable between a radially compressed state and a radially expanded state, wherein the frame elongates in an axial direction when radially compressed from the radially expanded state to the radially compressed state. Leaflets are coupled to the frame such that when the frame is in the radially expanded state, the leaflets have slack in an axial direction, wherein when the frame is radially compressed to a partially radially compressed state between the radially expanded state and the radially compressed state, the leaflets are in a relaxed state, and wherein when the frame is in the radially compressed state, the leaflets are stretched in the axial direction.

公开(公告)号：US20220287851A1

公开(公告)日：2022-09-15

申请号：US17805015

申请日：2022-06-01

Applicant: Edwards Lifesciences Corporation

Inventor： Eran Goldberg ,  Noam Nir

IPC: A61F2/48 ,  A61F2/24 ,  A61B5/00 ,  G16H40/63 ,  H02K7/18 ,  H02K11/00 ,  H02S10/40 ,  H02S40/38

Abstract: A valve monitoring assembly, constituted of: a prosthetic valve, constituted of a frame and leaflets positioned at least partially within the frame, that regulate blood flow through the prosthetic valve; and a monitoring apparatus constituted of: at least one sensor associated with the prosthetic valve, wherein the at least one sensor is selected from the group consisting of: flow sensor, pressure sensor, and temperature sensor; a local control circuitry; at least one communication component configured to wirelessly transmit signals; and an energy harvesting power source, configured to be secured to a patient and comprising a self-powered energy harvesting mechanism and an energy storage member, wherein the energy storage member is configured to store energy generated by the self-powered energy harvesting mechanism, and wherein the energy harvesting power source is configured to supply power to the at least one sensor, the local control circuitry and/or the at least one communication component.

公开(公告)号：US20220257367A1

公开(公告)日：2022-08-18

申请号：US17732985

申请日：2022-04-29

Applicant: Edwards Lifesciences Corporation

Inventor： Yair A. Neumann ,  Oren Cohen ,  Khen Perlmutter ,  Eitan Atias ,  Noam Miller ,  Eran Goldberg ,  Anatoly Dvorsky ,  Tamir S. Levi ,  Haim Yushtein ,  Danny M. Garmahi ,  Ziv Yohanan ,  Michael Bukin ,  Noam Nir ,  Elena Sherman ,  Gideon Sagi

IPC: A61F2/24

Abstract: An implantable prosthetic valve can include a frame movable between a radially compressed and a radially expanded configuration. The frame can include a first strut having a first locking feature disposed on a radially facing inner surface of the strut and a second strut having a second locking feature disposed on a radially facing outer surface of the strut. The first and second locking features can engage each other so as to allow pivoting of the first and second struts relative to one another in a first direction upon radial expansion of the frame and resist pivoting of the first and second struts relative to one another in a second direction to resist radial compression of the frame.

公开(公告)号：US20220168100A1

公开(公告)日：2022-06-02

申请号：US17671180

申请日：2022-02-14

Applicant: Edwards Lifesciences Corporation

Inventor： Noam Nir

IPC: A61F2/24

Abstract: A prosthetic valve assembly includes a radially expandable and compressible annular frame. The frame includes a plurality of interconnected struts, which include a plurality of inner struts and a plurality of outer struts. The inner struts overlap adjacent outer struts at a plurality of pivot joints. Radial expansion or compression of the annular frame causes the inner struts to pivot relative to the outer struts at the pivot joints. The assembly also includes a valvular structure inside the frame having a plurality of leaflets that regulate blood flow through the frame. Some of the struts include recessed portions and other struts that cross the recessed portions include segments that are seated in the recessed portions at the pivot joints. This provides a continuous or flush inner or outer surface of the frame.

公开(公告)号：US20220160505A1

公开(公告)日：2022-05-26

申请号：US17669138

申请日：2022-02-10

Applicant: Edwards Lifesciences Corporation

Inventor： Noam Nir ,  Michael Bukin ,  Ziv Yohanan ,  Tamir S. Levi ,  Elena Sherman

IPC: A61F2/24

Abstract: Disclosed are techniques for construction of prosthetic heart valves, particularly techniques for attachment of scalloped edges of valvular leaflets to struts of mechanical frames using sutures and/or other materials as intermediate coupling members. In some embodiments, the scalloped edges of the leaflets are coupled to the segments of the struts of the frame via suture loops that are oriented transverse to the scalloped edges of the leaflets. In some embodiments, central portions of scallop line segments are attached to the scalloped edges of the leaflets and are not attached to the frame. In some embodiments, strut segments are tapered to limit translation of suture loops. In some embodiments, a cloth strip couples the scalloped edges of the leaflets to frame struts. In some embodiments, the scalloped edge is attached to adjacent segments of intersecting struts via sliding suture loops, where the adjacent segments join at a common pivot joint.

公开(公告)号：US20210169630A1

公开(公告)日：2021-06-10

申请号：US17174784

申请日：2021-02-12

Applicant: Edwards Lifesciences Corporation

Inventor： Noam Nir ,  Carmel Peleg ,  Tomer Saar ,  Alexander Barash ,  David Maimon

IPC: A61F2/00 ,  A61F2/24

Abstract: Disclosed herein is a storage container for an expandable prosthetic heart valve that crimps the valve upon opening the container and removal of the valve from the container. The container includes a housing sized to receive the heart valve in its expanded configuration and a crimping mechanism. The crimping mechanism is incorporated into the container and engages the heart valve so as to operably convert the heart valve from its expanded configuration to its smaller crimped configuration upon opening the container and removing the valve.

公开(公告)号：US20210085454A1

公开(公告)日：2021-03-25

申请号：US17114251

申请日：2020-12-07

Applicant: Edwards Lifesciences Corporation

Inventor： Alexander Barash ,  Yair A. Neumann ,  Tomer Saar ,  Ziv Yohanan ,  Noam Nir

IPC: A61F2/24

Abstract: In one embodiment, a method of assembling a prosthetic valve can comprise forming a radially expandable and compressible frame by pivotally joining together a plurality of struts without requiring individual rivets. In some embodiments, the frame is formed by interweaving the struts, which can be joined using integral hinges formed in the struts, such as by performing alternate cuts on the struts, bending the struts to form stopper tabs adjacent to joints and/or drilling holes in the struts to facilitate interconnecting struts at joints, or otherwise forming integral hinges and corresponding holes at junction points between the struts. In other embodiments, separate hinges are provided to interconnect the struts. In still other embodiments, separate flanged rivets are provided to connect the struts.

公开(公告)号：US10925730B2

公开(公告)日：2021-02-23

申请号：US15956031

申请日：2018-04-18

Applicant: Edwards Lifesciences Corporation

Inventor： David Maimon ,  Noam Nir ,  Tomer Saar

IPC: A61F2/24

Abstract: A method for improving leaflet prolapse and/or valve regurgitation associated with a heart valve involves delivering a spacer device into a ventricle of a heart using a delivery system comprising a catheter, fixing the spacer device to a wall of the ventricle, expanding the spacer device to reposition a papillary muscle disposed in the ventricle away from the wall, the papillary muscle being connected to a leaflet of an atrioventricular heart valve via chordae tendineae, and releasing the spacer device from the catheter.