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公开(公告)号：US20240173129A1
公开(公告)日：2024-05-30
申请号：US18519557
申请日：2023-11-27
发明人： Noam Nir , Michael Bukin
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/243 , A61F2002/9511 , A61F2250/0071
摘要： A skirt for an implantable prosthetic device can include an annular fabric matrix radially expandable from a radially compressed configuration to a first diameter upon application of a radially outwardly directed force via the implantable prosthetic device, and a plurality of frangible restriction filaments embedded in the fabric matrix. Each restriction filament can have a selected maximum diameter different from that of at least one of the other restriction filaments, and each restriction filament can break when a radially outwardly directed force applied to the restriction filament exceeds a predetermined threshold.
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公开(公告)号：US20230372093A1
公开(公告)日：2023-11-23
申请号：US18358845
申请日：2023-07-25
发明人： Michael Bukin , Nikolai Gurovich , Noam Nir , Tomer Saar , Tamir S. Levi
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2250/0069
摘要： The present invention relates to implantable prosthetic devices, and more particularly, to 3D-shaped skirts having various coatings and/or configurations thereof.
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公开(公告)号：US20230240843A1
公开(公告)日：2023-08-03
申请号：US18131325
申请日：2023-04-05
发明人： Haim Yushtein , Noam Nir , Michael Bukin , David Maimon
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2403
摘要： An implantable prosthetic device can include a radially expandable and compressible frame including an inflow end portion and an outflow end portion. The frame can include an expansion and locking mechanism comprising a member having a first set of lateral extensions disposed adjacent an outflow end and a second set of lateral extensions axially spaced from the first set, each lateral extension comprising a bore extending into the lateral extension. The frame can further comprise a commissure attachment member having a first set of arms each extending into a respective inner bore of the first set of lateral extensions and a second set of arms each extending into a respective inner bore of the second set of lateral extensions such that the commissure attachment member is restrained from movement relative to the expansion and locking mechanism in the radial and axial directions.
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4.发明公开公开(公告)号：US20230190463A1
公开(公告)日：2023-06-22
申请号：US18110705
申请日：2023-02-16
发明人： Noam Nir
IPC分类号： A61F2/24
CPC分类号： A61F2/243 , A61F2/2466
摘要： An expansion and locking mechanism for a prosthetic valve and associated methods are disclosed. As one example, an expansion and locking mechanism for an implantable prosthetic device can include a first member coupled to a frame of the device and including at least one extension member extending in a circumferential direction and having a free end biased radially inward, into an interior of the first member and a second member coupled to the frame at a second location spaced apart from the first location, the second member extending at least partially inside the first member and comprising a plurality of radial extensions spaced apart from one another along a portion of a length of the second member, the plurality of radial extensions arranged in a first side of the second member that is arranged opposite a second side of the second member, the second side not including any radial extensions.
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公开(公告)号：US20230157802A1
公开(公告)日：2023-05-25
申请号：US18094864
申请日：2023-01-09
发明人： Noam Nir , Carmel Peleg , Tomer Saar , Alexander Barash , David Maimon
CPC分类号： A61F2/0095 , A61F2/24 , A61F2/9525 , A61F2/9522 , A61F2/9524
摘要： Disclosed herein is a storage container for an expandable prosthetic heart valve that crimps the valve upon opening the container and removal of the valve from the container. The container includes a housing sized to receive the heart valve in its expanded configuration and a crimping mechanism. The crimping mechanism is incorporated into the container and engages the heart valve so as to operably convert the heart valve from its expanded configuration to its smaller crimped configuration upon opening the container and removing the valve.
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公开(公告)号：US20220323211A1
公开(公告)日：2022-10-13
申请号：US17852136
申请日：2022-06-28
IPC分类号： A61F2/24
摘要： An assembly and associated method for a commissure of a prosthetic heart valve is disclosed. As one example, a method includes: forming a plurality of commissures with the plurality of leaflets, wherein each commissure is formed by: pairing a first commissure tab of a first leaflet with an adjacent, second commissure tab of a second leaflet, coupling a main body of a support strip to the first and second commissure tabs via primary sutures, folding a tab portion of the support strip over the main body, and coupling the tab portion of the support strip to the main body via secondary sutures, and for each commissure, securing the commissure to a respective support portion of a frame of the prosthetic heart valve.
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公开(公告)号：US20220234306A1
公开(公告)日：2022-07-28
申请号：US17719262
申请日：2022-04-12
发明人： Itai Pelled , Elena Sherman , Eran Goldberg , Kevin D. Rupp , Noam Nir
摘要： A prosthetic heart valve has a radially expandable and collapsible annular frame, the frame having an inflow end and an outflow end and defining a longitudinal axis along a lumen of the prosthetic heart valve when it is in the expanded configuration. A leaflet structure is positioned within the frame and secured thereto. The prosthetic heart valve also has a laminate sealing member including a plurality of layers heat-bonded together to encapsulate at least a portion of the frame. The laminate sealing member extends along the longitudinal axis in an upstream direction and doubles back toward the outflow end of the frame at a fold line to form a cuff, and an edge portion of the laminate sealing member is secured to a main portion of the laminate sealing member downstream of the fold line such that the cuff forms an inflow end of the laminate sealing member.
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公开(公告)号：US20220023036A1
公开(公告)日：2022-01-27
申请号：US17496670
申请日：2021-10-07
发明人： Tamir S. Levi , Elena Sherman , Noam Nir
IPC分类号： A61F2/24
摘要： A method of assembling a prosthetic heart valve comprises securing a suture loop having at least first and second windings to an outflow edge portion of an inner skirt. The first and second windings are arranged in a repeating pattern of figure-eight shape curves and each winding has a plurality of first sections attached to the outflow edge portion of the inner skirt and a plurality of second sections unattached to the inner skirt. The inner skirt is placed inside of an annular frame and the second sections of the first and second windings are placed over apices of an outflow end of the frame such that the second sections of the first and second windings reside outside of the frame. The second sections of the windings are inserted inwardly through openings in the frame and attached to selected locations on the inner skirt.
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公开(公告)号：US10918473B2
公开(公告)日：2021-02-16
申请号：US16036190
申请日：2018-07-16
发明人： Noam Nir , Carmel Peleg , Tomer Saar , Alexander Barash , David Maimon
摘要： Disclosed herein is a storage container for an expandable prosthetic heart valve that crimps the valve upon opening the container and removal of the valve from the container. The container includes a housing sized to receive the heart valve in its expanded configuration and a crimping mechanism. The crimping mechanism is incorporated into the container and engages the heart valve so as to operably convert the heart valve from its expanded configuration to its smaller crimped configuration upon opening the container and removing the valve.
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公开(公告)号：US10470876B2
公开(公告)日：2019-11-12
申请号：US15345857
申请日：2016-11-08
发明人： Nikolay Gurovich , Mohammad Jafari , Liron Tayeb , Ilan Tamir , Ziv Yohanan , Noam Nir , David Maimon , Boaz Manash
IPC分类号： A61F2/24
摘要： Embodiments of prosthetic valves for implantation within a native mitral valve are provided. A prosthetic valve may comprise a radially compressible main body and a one-way valve portion. The prosthetic valve may further comprise one or more ventricular anchors coupled to the main body and disposed outside of the main body. The ventricular anchors may be configured such that a reduced profile of the prosthetic valve is possible. A space may be provided between an outer surface of the main body and the ventricular anchors for receiving native mitral valve leaflets. The prosthetic valve may include an atrial sealing member adapted for placement above the annulus of the mitral valve. Methods and devices for receiving the native mitral valve leaflets between the ventricular anchors and the main body are described.
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