摘要:
The present invention relates to a method of treating asthma by raising the pH of the airways of an individual. The effect can be mediated directly by administering a pharmaceutically acceptable basic solution or alternatively, the effect can be mediated by enhancing the activity of glutaminase.
摘要:
Forceps for grasping tissue during a medical procedure. The forceps include a body, a jaw pivotally mounted on the body for movement between a grasping position and a releasing position, and a lever operatively connected to the jaw to drive the jaw from the grasping position to the releasing position. The forceps include a digit engagement member rotatably mounted on the lever. The digit engagement member has an engagement surface configured to engage a digit of an operator's hand during use. The engagement surface rotates relative to the lever as the lever drives the jaw from the releasing position to the grasping position
摘要:
A method and apparatus for completing a lateral channel from an existing oil or gas well includes a well perforating tool for perforating a well casing at a preselected depth, and a lateral alignment tool for directing a flexible hose and blaster nozzle through a previously made perforation in the casing to complete the lateral channel. The disclosed apparatus also is effective to provide an expanded groove within the earth strata beyond the well casing. The apparatus eliminates the need to maintain the precise alignment of a downhole “shoe” in order to direct the flexible hose and blaster nozzle through a previously made perforation through the well casing.
摘要:
One possible embodiment for the invention could be an additive delivery device for an irrigation system having at least one vacuum pressure breaker, whereby the additive delivery device can attach to the irrigation system without altering or otherwise changing the preexisting components of the vacuum pressure breaker. The attachment could occur at two pre-existing attachment points of the pressure vacuum breaker which were originally and substantially designed for other uses other than the introduction of additive(s) into the interior of the vacuum pressure breaker. The additive delivery device could comprise a container for holding and mixing additive with water from the irrigation system and a connector device for making container's interior and pressure vacuum breaker's interior substantially continuous. The connector device could utilize a passage restriction device to direct water from vacuum pressure breaker to the container and to direct water-additive solution from the container to the vacuum pressure breaker.
摘要:
The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2, FGFR-1, PDGFR, HER-1, HER-2, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.