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公开(公告)号:US5053393A
公开(公告)日:1991-10-01
申请号:US540953
申请日:1990-06-20
申请人: Foe S. Tjoeng , Larry P. Feigen , Steven P. Adams
发明人: Foe S. Tjoeng , Larry P. Feigen , Steven P. Adams
CPC分类号: C07C279/14 , C07K5/021 , C07K5/06113 , A61K38/00
摘要: N-[8-[(Aminoiminomethyl)amino]-1-oxooctyl]-N-L-.alpha.-aspartyl-L-phenylanine is disclosed as a highly potent inhibitor of platelet aggregation.
摘要翻译: 公开了N- [8 - [(氨基亚氨基甲基)氨基] -1-氧代辛基] -N-L-天冬酰基-L-苯丙氨酸作为血小板聚集的高效抑制剂。
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公开(公告)号:US5026686A
公开(公告)日:1991-06-25
申请号:US305148
申请日:1989-02-01
IPC分类号: A61K38/00 , C07K14/005 , C07K14/18
CPC分类号: C07K14/005 , A61K38/00 , C12N2770/36122
摘要: Novel antiviral peptides are disclosed which have a sequence of about 4 to 10 amino acids and which are substantially identical to a small portion of the cytoplasmic domain of a glycoprotein in a virus that contains a lipid-bilayer in its structure.
摘要翻译: 公开了新型抗病毒肽,其具有约4至10个氨基酸的序列,并且其基本上与其结构中含有脂质 - 双层的病毒中的糖蛋白的细胞质结构域的一小部分相同。
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公开(公告)号:US4740588A
公开(公告)日:1988-04-26
申请号:US924543
申请日:1986-10-29
申请人: Steven P. Adams , Dwight A. Towler , Luis Glaser
发明人: Steven P. Adams , Dwight A. Towler , Luis Glaser
CPC分类号: C07K7/06
摘要: A peptide substrate for myristoylating enzymes is disclosed having an amino acid sequence selected from the group consisting of the following sequences or a physiologically acceptable amide or salt derivative thereof: ##STR1## wherein R=Ala, Asn, Gln or Ser;S=Ala, Arg, Gln, Glu, Phe or Ser;T=Ala or Lys;W=Ala or Ser;X=Ala, Tyr, or Lys;Y=Arg or Pro; andZ=Arg, Leu or Lys.
摘要翻译: 公开了用于肉豆蔻酰化酶的肽底物,其具有选自以下序列或其生理上可接受的酰胺或盐衍生物的氨基酸序列:其中R = Ala ,Asn,Gln或Ser; S = Ala,Arg,Gln,Glu,Phe或Ser; T = Ala或Lys; W = Ala或Ser; X = Ala,Tyr或Lys; Y = Arg或Pro; Z = Arg,Leu或Lys。
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