Dextran esters, the preparation thereof and the use thereof for coating
or embedding drugs
    52.
    发明授权
    Dextran esters, the preparation thereof and the use thereof for coating or embedding drugs 失效
    葡聚糖酯,其制备方法及其用于涂覆或包埋药物的用途

    公开(公告)号:US5739122A

    公开(公告)日:1998-04-14

    申请号:US612975

    申请日:1996-03-11

    摘要: Dextran esters with a molecular weight of 10,000-10,000,000 and ester side chains which are derived from acids with 6-18 carbon atoms, where the degree of esterification is adjusted, depending on the number of carbon atoms in the side chains and the molecular weight, to a value of 0.04-1.1 so that the dextran esters are insoluble in water at room temperature and are broken down by colonic bacteria, and their use for coating and/or embedding pharmaceutical active ingredients or drug formulations.

    摘要翻译: PCT No.PCT / EP94 / 02988 Sec。 371日期:1996年3月11日 102(e)1996年3月11日PCT 1994年9月7日PCT PCT。 出版物WO95 / 07936 日期1995年3月23日分子量为10,000-10,000,000的葡聚糖酯和衍生自具有6-18个碳原子的酸的酯侧链,其中调节酯化度取决于侧链中的碳原子数 和分子量为0.04-1.1,使得葡聚糖酯在室温下不溶于水,并被结肠细菌分解,以及它们用于涂覆和/或包埋药物活性成分或药物制剂的用途。