公开(公告)号：US20070027186A1

公开(公告)日：2007-02-01

申请号：US11470741

申请日：2006-09-07

Applicant: Jiacheng Zhou ,  Lynette Oh ,  Philip Ma ,  Hui-Yin Li ,  Pasquale Confalone

Inventor： Jiacheng Zhou ,  Lynette Oh ,  Philip Ma ,  Hui-Yin Li ,  Pasquale Confalone

IPC: A61K31/4545 ,  A61K31/4439 ,  C07D417/02 ,  C07D403/02 ,  C07D401/04

CPC classification number: C07D211/88 ,  C07D211/86 ,  C07D471/04

Abstract: A novel process and intermediates thereof for making 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones of the type shown below from appropriate phenyl hydrazines is described. These compounds are useful as factor Xa inhibitors.

Abstract translation: 描述了由合适的苯肼制备下列所示类型的4,5-二氢 - 吡唑并[3,4-c]吡啶-2-酮的新方法及其中间体。 这些化合物可用作因子Xa抑制剂。

公开(公告)号：US20060111404A1

公开(公告)日：2006-05-25

申请号：US11284220

申请日：2005-11-21

Applicant: Chu-Biao Xue ,  Brian Metcalf ,  Hui-Yin Li ,  Hao Feng ,  Joseph Glenn

Inventor： Chu-Biao Xue ,  Brian Metcalf ,  Hui-Yin Li ,  Hao Feng ,  Joseph Glenn

IPC: A61K31/4439 ,  C07D403/02

CPC classification number: C07D401/08 ,  C07D403/08

Abstract: The present invention pertains to bis(methanesulfonic acid), bis(ethanesulfonic acid), and camphoric acid salts of chemokine receptor inhibitor N-[2-({(3R)-1-[trans-4-hydroxy-4-(6-methoxypyridin-3-yl)-cyclohexyl]-pyrrolidin-3-yl}amino)-2-oxoethyl]-3-(trifluoromethyl)-benzamide, methods of preparing the same, and methods of using the same.

Abstract translation: 本发明涉及趋化因子受体抑制剂N- [2 - （{（3R）-1- [反-4-羟基-4-（6-甲氧基苯磺酸） 甲氧基吡啶-3-基） - 环己基] - 吡咯烷-3-基}氨基）-2-氧代乙基] -3-（三氟甲基） - 苯甲酰胺，其制备方法及其使用方法。

公开(公告)号：US20050219264A1

公开(公告)日：2005-10-06

申请号：US10817516

申请日：2004-04-01

Applicant: Heung-Yeung Shum ,  Jian Sun ,  Shuntaro Yamazaki ,  Yin Li

Inventor： Heung-Yeung Shum ,  Jian Sun ,  Shuntaro Yamazaki ,  Yin Li

IPC: G06K9/00 ,  G06T15/20 ,  G09G5/00

CPC classification number: G06T15/205

Abstract: Techniques are disclosed to produce virtual views of a complex scene. The virtual views are substantially free from aliasing even when using a relatively sparse set of images of the scene. In a described implementation, a scene is split into one or more coherent layers. The boundaries of the coherent layers are propagated across a plurality of frames corresponding to the scene. The splitting may be further refined (e.g., in accordance with user feedback) to present a virtual view of the scene.

Abstract translation: 公开了产生复杂场景的虚拟视图的技术。 即使当使用场景的相对稀疏的图像集时，虚拟视图也基本上没有混叠。 在所描述的实现中，场景被分成一个或多个相干层。 相干层的边界跨越对应于场景的多个帧传播。 可以进一步改进分割（例如，根据用户反馈）来呈现场景的虚拟视图。

公开(公告)号：US06329527B1

公开(公告)日：2001-12-11

申请号：US09685127

申请日：2000-10-10

Applicant: Jiacheng Zhou ,  Lynette May Oh ,  Pasquale N. Confalone ,  Hui-yin Li ,  Philip Ma

Inventor： Jiacheng Zhou ,  Lynette May Oh ,  Pasquale N. Confalone ,  Hui-yin Li ,  Philip Ma

IPC: C07D26120

CPC classification number: C07D231/06 ,  C07D231/14 ,  C07D413/04

Abstract: A novel process for making 1,3,5-trisubstituted pyrazoles of the type shown below from appropriate phenyl hydrazines is described. These compounds are useful as factor Xa inhibitors.

Abstract translation: 描述了从合适的苯肼制备下列类型的1,3,5-三取代吡唑的新方法。这些化合物可用作因子Xa抑制剂。

公开(公告)号：US06194569B1

公开(公告)日：2001-02-27

申请号：US09385271

申请日：1999-08-30

Applicant: Patrick J. Sheeran ,  Luigi Anzalone ,  Hui-Yin Li ,  Joseph M. Fortunak ,  Louis Storace

Inventor： Patrick J. Sheeran ,  Luigi Anzalone ,  Hui-Yin Li ,  Joseph M. Fortunak ,  Louis Storace

IPC: C07D40312

CPC classification number: C07D405/12 ,  C07D205/08

Abstract: Processes for the preparation of [S-(R,S)]-N-[1,3-benzodioxol-5-yl)butyl]-3,3-diethyl-2[4-[4-methyl-1-piperazinyl)carbonyl]phenoxy]-4-oxo-l-azetidine carboxamide, a useful inhibitor of human leukocyte elastase (HLE), are described. The process including (a) contacting a compound of formula (II): with a compound of formula (III): in a first polar solvent system in the presence of an aqueous base and a phase transfer catalyst, to form the title compound, or a salt form thereof.

Abstract translation: 制备[S-（R，S）] - N- [1,3-苯并间二氧杂环戊烯-5-基）丁基] -3,3-二乙基-2 [4- [4-甲基-1-哌嗪基] 羰基]苯氧基] -4-氧代-1-氮杂环丁烷甲酰胺，是人类白细胞弹性蛋白酶（HLE）的有用抑制剂。 该方法包括（a）使式（II）化合物与式（III）化合物在碱性水溶液和相转移催化剂存在下在第一极性溶剂体系中接触以形成标题化合物，或 其盐形式。

公开(公告)号：US5932749A

公开(公告)日：1999-08-03

申请号：US822996

申请日：1997-03-21

Applicant: Hui-Yin Li ,  Luigi Anzalone ,  Robert Eugene Waltermire

Inventor： Hui-Yin Li ,  Luigi Anzalone ,  Robert Eugene Waltermire

IPC: A61K31/00 ,  A61K31/495 ,  A61K31/496 ,  A61P43/00 ,  C07D317/58 ,  C07D405/12

CPC classification number: C07D317/58

Abstract: Processes for the preparation of R-.alpha.-propyl-piperonyl amine and its analogs, such compounds being useful intermediates in the preparation of elastase inhibitors, and intermediates useful for making R-.alpha.-propyl-piperonyl amine are described.

Abstract translation: 描述了制备R-丙基 - 胡椒基胺及其类似物的方法，这些化合物是制备弹性蛋白酶抑制剂的有用中间体，以及可用于制备R-丙基 - 胡椒基胺的中间体。

公开(公告)号：USD935341S1

公开(公告)日：2021-11-09

申请号：US29769166

申请日：2021-02-03

Applicant: Yin Li

Designer： Yin Li

公开(公告)号：US08680108B2

公开(公告)日：2014-03-25

申请号：US12972155

申请日：2010-12-17

Applicant: Yun-Long Li ,  Andrew P. Combs ,  Eddy W. Yue ,  Hui-Yin Li

Inventor： Yun-Long Li ,  Andrew P. Combs ,  Eddy W. Yue ,  Hui-Yin Li

IPC: A61K31/52 ,  A61P13/12 ,  A61P11/06 ,  A61P37/08 ,  A61P19/02 ,  A61P17/06 ,  A61P35/02 ,  A61P35/00 ,  C12N9/99 ,  C07D473/00

CPC classification number: C07D473/34 ,  C07D473/16

Abstract: The present invention provides fused aryl and heteroaryl derivatives of Formula I: wherein X, V, Y, U, W, Z, R1, R2, Cy, and Ar are defined herein, that modulate the activity of phosphoinositide 3-kinases (PI3Ks) and are useful in the treatment of diseases related to the activity of PI3Ks including, for example, inflammatory disorders, immune-based disorders, cancer, and other diseases.

Abstract translation: 本发明提供式I的稠合芳基和杂芳基衍生物：其中X，V，Y，U，W，Z，R 1，R 2，Cy和Ar如本文所定义，其调节磷酸肌醇3-激酶（PI3K）的活性， 并且可用于治疗与PI3Ks的活性相关的疾病，包括例如炎性疾病，基于免疫的疾病，癌症和其它疾病。

公开(公告)号：USD685072S1

公开(公告)日：2013-06-25

申请号：US29395593

申请日：2012-02-24

Applicant: Yubin Li ,  Huanlong Wu ,  Liang Li ,  Kangquan Xu ,  Yin Li

Designer： Yubin Li ,  Huanlong Wu ,  Liang Li ,  Kangquan Xu ,  Yin Li

公开(公告)号：US08060351B2

公开(公告)日：2011-11-15

申请号：US12175499

申请日：2008-07-18

Applicant: I-Yin Li ,  Jean-Fu Kiang

Inventor： I-Yin Li ,  Jean-Fu Kiang

IPC: G06F17/50

CPC classification number: G06F17/5045

Abstract: An LCD display design system and method are disclosed. The method includes performing operations by a variety of operation modules after initial parameters are input and an operation type is selected, so as to generate operation results and transfer the operation results to an integration module; integrating the operation results by an integration module to generate a correspondence relation such as an operation window, a compare-table or an equation, and further transferring the operation results and the correspondence relation to an output module such that the output module can display performance variations of a variety of designs corresponding to the different initial parameters. Therefore, the present invention provides a user with a convenient way to obtain optimal design parameters for designing a display pixel circuit.

Abstract translation: 公开了一种LCD显示设计系统和方法。 该方法包括：在输入初始参数并选择操作类型之后，通过各种操作模块执行操作，从而产生操作结果并将操作结果传送到集成模块; 通过集成模块对运算结果进行积分，生成操作窗口，比较表或方程等对应关系，并将运算结果和对应关系进一步传送到输出模块，使得输出模块可以显示性能变化 的各种设计对应于不同的初始参数。 因此，本发明为用户提供了一种方便的方法来获得用于设计显示像素电路的最佳设计参数。