专利检索 ap:("Dennis Fiegen" OR "Sandra Handschuh" OR "Silke Hobbie" OR "Matthias Hoffmann" OR "Takeshi Kono" OR "Yayoi Sato" OR "Andreas Schnapp" OR "Annette Schuler-Metz") AND inv:"Annette Schuler-Metz" 第 7 页

61.

发明申请
SUBSTITUTED PROLINAMIDES, THE PREPARATION THEREOF AND THE USE THEREOF AS PHARMACEUTICAL COMPOSITIONS 有权
标题翻译：取代的丙氨酸，其制备方法及其作为药物组合物的用途

公开(公告)号：US20090048231A1

公开(公告)日：2009-02-19

申请号：US12278296

申请日：2007-02-13

申请人： Henning Priepke , Georg Dahmann , Kai Gerlach , Herbert Nar , Roland Pfau , Annette Schuler-Metz , Wolfgang Wienen

发明人： Henning Priepke , Georg Dahmann , Kai Gerlach , Herbert Nar , Roland Pfau , Annette Schuler-Metz , Wolfgang Wienen

IPC分类号： A61K31/55 , C07D403/12 , A61P7/02

CPC分类号： C07D401/14 , C07D403/12

摘要： The present invention provides new substituted prolinamides of the general formula (I) in which D, L, E, G, J, M, R3, R4, R5, and R13 are defined as in claim 1, their tautomers, their enantiomers, their diastereomers, their mixtures and their salts, more particularly their physiologically tolerated salts with organic or inorganic acids or bases, which exhibit valuable properties.

摘要翻译： 本发明提供了通式（I）的新的取代的脯氨酰胺，其中D，L，E，G，J，M，R 3，R 4，R 5和R 13如权利要求1中所定义，它们的互变异构体，非对映异构体，它们的混合物和它们的盐，更特别是它们与有机或无机酸或碱的生理学上可接受的盐，其表现出有价值的性质。

62.

发明申请
SUBSTITUTED PROLINAMIDES, MANUFACTURING, AND THE USE THEREOF AS MEDICAMENTS 有权
标题翻译：取代的生物素，制造及其作为药物的用途

公开(公告)号：US20080139605A1

公开(公告)日：2008-06-12

申请号：US11749204

申请日：2007-05-16

申请人： Kai Gerlach , Georg Dahmann , Herbert Nar , Roland Pfau , Henning Priepke , Annette Schuler-Metz , Wolfgang Wienen

发明人： Kai Gerlach , Georg Dahmann , Herbert Nar , Roland Pfau , Henning Priepke , Annette Schuler-Metz , Wolfgang Wienen

IPC分类号： A61K31/4375 , A61K31/4725 , C07D217/22 , C07D471/04

CPC分类号： C07D401/12 , C07D401/14 , C07D471/04

摘要： The present invention relates to new substituted prolinamides of general formula (I) wherein D, L, E, G, J, M, R3, R4, R5 and R13 are defined as in the specification, the tautomers, the enantiomers, the diastereomers, the mixtures, and the salts thereof.

摘要翻译： 本发明涉及通式（I）的新的取代的脯氨酸酰胺，其中D，L，E，G，J，M，R 3，R 4，R SUP 说明书中定义的“5”和“R”13互变异构体，对映异构体，非对映异构体，混合物及其盐。

63.

发明申请
SUBSTITUTED BIARYLS, PROCESS FOR THEIR MANUFACTURE AND USE THEREOF AS MEDICAMENTS 审中-公开
标题翻译：替代生物制品及其制造工艺及其作为药物的使用

公开(公告)号：US20080051578A1

公开(公告)日：2008-02-28

申请号：US11466923

申请日：2006-08-24

申请人： Georg Dahmann , Kai Gerlach , Roland Pfau , Henning Priepke , Wolfgang Wienen , Annette Schuler-Metz , Herbert Nar

发明人： Georg Dahmann , Kai Gerlach , Roland Pfau , Henning Priepke , Wolfgang Wienen , Annette Schuler-Metz , Herbert Nar

IPC分类号： C07D279/06 , C07D279/12 , C07D273/04

CPC分类号： C07D409/14 , C07D413/10 , C07D413/14 , C07D417/14

摘要： The present invention relates to compounds of general formula (I) wherein A, B, L, R1, R2, R3a and R3b are defined as in the specification, the tautomers, the enantiomers, the diastereomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, which have valuable properties.

摘要翻译： 本发明涉及通式（I）的化合物，其中A，B，L，R 1，R 2，R 3，R 3和R 3 在本说明书中定义了互变异构体，对映异构体，非对映异构体，其混合物及其盐，特别是其与无机或有机酸或碱的生理上可接受的盐，其具有有价值的性质。