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公开(公告)号:US07232562B2
公开(公告)日:2007-06-19
申请号:US10369495
申请日:2003-02-19
CPC分类号: A61K47/60
摘要: A conjugate exhibiting interferon gamma activity and comprising at least one first non-polypeptide moiety covalently linked to an IFG polypeptide, the polypeptide comprising an amino acid sequence that differs from that of a parent IFNG polypeptide in at least one introduced and/or at least one removed amino acid residue comprising an attachment group for the non-polypeptide moiety. The conjugate may be used for treatment of various diseases.
摘要翻译: 一种显示干扰素γ活性并包含与IFG多肽共价连接的至少一个第一非多肽部分的缀合物,所述多肽包含与至少一个引入的和/或至少一个的IFIF多肽的母体IFNG多肽不同的氨基酸序列 去除的氨基酸残基包含非多肽部分的连接基团。 缀合物可用于治疗各种疾病。