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65 条记录 (耗时 0.021 秒)

    Immunoassay method for measuring immunological antigen in fluid sample
    62.
    发明授权
    Immunoassay method for measuring immunological antigen in fluid sample 失效
    用于测量流体样品中免疫学抗原的免疫测定方法

    公开(公告)号：US4613567A

    公开(公告)日：1986-09-23

    申请号：US520072

    申请日：1983-08-03

    申请人： Seikichi Yasoshima ,  Mikio Koyama ,  Kenichiro Okaniwa

    发明人： Seikichi Yasoshima ,  Mikio Koyama ,  Kenichiro Okaniwa

    IPC分类号： G01N33/543 ,  C12Q1/00 ,  G01N21/64 ,  G01N33/558

    CPC分类号： G01N33/54386 ,  Y10S435/805 ,  Y10S435/97 ,  Y10S436/807

    摘要： There is disclosed an immunoassay comprising carrying out an immunological reaction by contacting a fluid sample with an element for immunoassay, having at least three layers of a first detecting layer, a blocking layer and a second detecting layer which are successively laminated, the element containing a substance capable of binding specifically to an immunologically active substance in a fluid sample only in either one of the first and the second detecting layers, and then measuring the detected quantities corresponding to the immunological reaction quantities from both of the first and the second detecting layers.The immunoassay by the use of the immunological analytical element according to this invention improves the precision immunoassay by measuring both of Bound and Free.

    摘要翻译： 公开了一种免疫测定，其包括通过使流体样品与用于免疫测定的元件接触而进行免疫反应，所述元件具有至少三层依次层压的第一检测层，阻挡层和第二检测层，所述元件含有 能够仅在第一和第二检测层中的任一个中在流体样品中特异性结合免疫活性物质的物质，然后测量对应于来自第一和第二检测层的免疫反应量的检测量。 通过使用根据本发明的免疫分析元件的免疫测定通过测量结合和自由来提高精确的免疫测定。

    Analytical element
    63.
    发明授权
    Analytical element 失效
    分析要素

    公开(公告)号：US4594224A

    公开(公告)日：1986-06-10

    申请号：US597818

    申请日：1984-04-09

    申请人： Kenichiro Okaniwa ,  Shozo Kikugawa ,  Mikio Koyama

    发明人： Kenichiro Okaniwa ,  Shozo Kikugawa ,  Mikio Koyama

    IPC分类号： G01N31/22 ,  C12Q1/54 ,  G01N33/52 ,  G01N21/78

    CPC分类号： G01N33/525 ,  C12Q1/54 ,  Y10S435/805

    摘要： There is presented an improved simple quantitative analytical element for analysis of components in a body fluid such as blood, having a reagent layer constituted of a hydrophilic colloid containing at least one reagent reactive with a component in a liquid sample provided on a support, and also a development layer of a fibrous structure on the reagent layer on the opposite side to the support. A liquid sample can be distributed uniformly through the reagent layer to enable quantitative analysis.

    摘要翻译： 提出了一种用于分析诸如血液的体液中的组分的改进的简单定量分析元件，其具有由含有至少一种与在载体上提供的液体样品中的组分反应的试剂的亲水胶体构成的试剂层，以及 在与载体相反的一侧上的试剂层上的纤维结构的显影层。 液体样品可以均匀地分布在试剂层中，以进行定量分析。

    Analytical element and method of use
    64.
    发明授权
    Analytical element and method of use 失效
    分析要素和使用方法

    公开(公告)号：US4486537A

    公开(公告)日：1984-12-04

    申请号：US419931

    申请日：1982-09-20

    申请人： Mikio Koyama ,  Kenichiro Okaniwa

    发明人： Mikio Koyama ,  Kenichiro Okaniwa

    IPC分类号： G01N31/22 ,  G01N33/52 ,  G01N21/78

    CPC分类号： G01N33/525 ,  Y10S435/805

    摘要： An analytical element comprising a light-transmissive and liquid-impervious support, at least one reagent layer containing at least one reagent which reacts with a component in a fluid sample and at least one development layer provided at a position on the reagent layer on the opposite side to that of the support for permitting the component in said fluid sample to permeate into the reagent layer, at least one layer of reagent layers being constituted of polymeric particulate units each having a core-shell multi-layer structure comprising a core, which is hydrophobic and substantially unswellable with a fluid sample, and a hydrophilic outer shell.

    摘要翻译： 一种分析元件，包括透光和液体不可渗透的载体，至少一个试剂层，其含有至少一种与流体样品中的组分反应的试剂，以及设置在相对的试剂层上的至少一个显影层 与允许所述流体样品中的组分渗透到试剂层中的载体的一侧，至少一层试剂层由聚合物颗粒单元构成，每个聚合物颗粒单元均具有包含芯的核 - 壳多层结构， 疏水性并且基本上不能与流体样品一起使用，以及亲水性外壳。