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公开(公告)号：US20070260091A1
公开(公告)日：2007-11-08
申请号：US11796395
申请日：2007-04-27
IPC分类号： C07C211/42
CPC分类号： C07C209/70 , C07C211/30
摘要： Provided is a process for preparing cinacalcet, (R)-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethane amine.
摘要翻译： 提供了制备西那卡塞，（R）-α-甲基-N- [3- [3-（三氟甲基）苯基]丙基] -1-萘甲烷胺的方法。
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62.发明授权Crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms 失效阿伐他汀半钙的晶体形式及其制备方法以及制备其他形式的新方法公开(公告)号：US07256212B2
公开(公告)日：2007-08-14
申请号：US11193089
申请日：2005-07-29
IPC分类号： A61K31/40 , C07D207/34
CPC分类号： C07D207/34 , A61K9/282 , A61K9/5021 , C07D405/06
摘要： The present invention provides novel forms of atorvastatin designated Forms VI, VIII, IX, X, XI and XII and novel processes for their preparation as well as processes for preparing atorvastatin Forms I, II, IV, V and amorphous atorvastatin.
摘要翻译： 本发明提供命名为形式VI，VIII，IX，X，XI和XII的阿托伐他汀的新形式及其制备方法以及制备阿托伐他汀形式I，II，IV，V和无定形阿托伐他汀的方法。
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公开(公告)号：US20070021616A1
公开(公告)日：2007-01-25
申请号：US11527083
申请日：2006-09-25
IPC分类号： C07F9/6506
CPC分类号： C07F9/6506
摘要： The invention relates to polymorphs of zoledronic acid and zoledronate sodium salts, amorphous zoledronate sodium salt, processes for making the polymorphs and amorphous zoledronate sodium salt, and pharmaceutical compositions containing the polymorphs and amorphous zoledronate sodium salt.
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公开(公告)号：US20050267198A1
公开(公告)日：2005-12-01
申请号：US11193112
申请日：2005-07-29
IPC分类号： A61K9/28 , A61K9/50 , A61K31/40 , A61K31/401 , A61P3/06 , A61P9/00 , B01D9/02 , C07D207/34 , C07D405/06
CPC分类号： C07D207/34 , A61K9/282 , A61K9/5021 , C07D405/06
摘要： The present invention provides novel forms of atorvastatin designated Forms VI, VIII, IX, X, XI and XII and novel processes for their preparation as well as processes for preparing atorvastatin Forms I, II, IV, V and amorphous atorvastatin.
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公开(公告)号：US20050261361A1
公开(公告)日：2005-11-24
申请号：US11193089
申请日：2005-07-29
IPC分类号： A61K9/28 , A61K9/50 , A61K31/40 , A61K31/401 , A61P3/06 , A61P9/00 , B01D9/02 , C07D207/34 , C07D405/06
CPC分类号： C07D207/34 , A61K9/282 , A61K9/5021 , C07D405/06
摘要： The present invention provides novel forms of atorvastatin designated Forms VI, VIII, IX, X, XI and XII and novel processes for their preparation as well as processes for preparing atorvastatin Forms I, II, IV, V and amorphous atorvastatin.
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公开(公告)号：US20050261359A1
公开(公告)日：2005-11-24
申请号：US11192672
申请日：2005-07-29
IPC分类号： A61K9/28 , A61K9/50 , A61K31/40 , A61K31/401 , A61P3/06 , A61P9/00 , B01D9/02 , C07D207/34 , C07D405/06
CPC分类号： C07D207/34 , A61K9/282 , A61K9/5021 , C07D405/06
摘要： The present invention provides novel forms of atorvastatin designated Forms VI, VIII, IX, X, XI and XII and novel processes for their preparation as well as processes for preparing atorvastatin Forms I, II, IV, V and amorphous atorvastatin.
摘要翻译： 本发明提供了形式为VI，VIII，IX，X，XI和XII的阿托伐他汀的新形式及其制备方法以及制备阿托伐他汀形式I，II，IV，V和无定形阿托伐他汀的方法。
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67.发明申请PROCESSES FOR PURIFYING VARENICLINE L-TARTRATE SALT AND PREPARING CRYSTALLINE FORMS OF VARENICLINE L-TARTRATE SALT 审中-公开稀释盐酸L-盐酸盐的制备方法和制备盐酸L-盐酸盐的晶体形式公开(公告)号：US20100010221A1
公开(公告)日：2010-01-14
申请号：US12473926
申请日：2009-05-28
申请人： Revital Lifshitz-Liron , Shalom Shabat , Sharon Tomer , Yuriy Raizi , Eyal Gilboa , Pramod Kumar Pandey
发明人： Revital Lifshitz-Liron , Shalom Shabat , Sharon Tomer , Yuriy Raizi , Eyal Gilboa , Pramod Kumar Pandey
IPC分类号： C07D471/04
CPC分类号： C07D471/08
摘要： Processes for purifying Varenicline base or the L-tartrate salt thereof and for preparing Varenicline L-tartrate crystalline forms A and B are provided.
摘要翻译： 提供了用于纯化瓦伦尼克碱碱或其L-酒石酸盐的方法和用于制备L-赖氨酸L-酒石酸盐结晶形式A和B的方法。
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68.发明授权Zoledronic acid crystal forms, zoledronate sodium salt crystal forms, amorphous zoledronate sodium salt, and processes for their preparation 失效唑来膦酸晶体形式，唑来膦酸钠盐晶体形式，无定形唑来膦酸钠盐及其制备方法公开(公告)号：US07582768B2
公开(公告)日：2009-09-01
申请号：US11527258
申请日：2006-09-25
IPC分类号： A61K31/675 , C07F9/06
CPC分类号： C07F9/6506
摘要： The invention relates to polymorphs of zoledronic acid and zoledronate sodium salts, amorphous zoledronate sodium salt, processes for making the polymorphs and amorphous zoledronate sodium salt, and pharmaceutical compositions containing the polymorphs and amorphous zoledronate sodium salt.
摘要翻译： 本发明涉及唑来膦酸和唑来膦酸钠盐，无定形唑来膦酸钠盐，制备多晶型物的方法和无定形唑来膦酸钠盐的多晶型物，以及含有多晶型物和无定形唑来膦酸钠盐的药物组合物。
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公开(公告)号：US07456297B2
公开(公告)日：2008-11-25
申请号：US11192674
申请日：2005-07-29
IPC分类号： C07D207/00
CPC分类号： C07D207/34 , A61K9/282 , A61K9/5021 , C07D405/06
摘要： The present invention provides novel forms of atorvastatin designated Forms VI, VIII, IX, X, XI and XII and novel processes for their preparation as well as processes for preparing atorvastatin Forms I, II, IV, V and amorphous atorvastatin.
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公开(公告)号：US07393967B2
公开(公告)日：2008-07-01
申请号：US11796395
申请日：2007-04-27
IPC分类号： C07C229/00
CPC分类号： C07C209/70 , C07C211/30
摘要： Provided is a process for preparing cinacalcet, (R)-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethane amine.
摘要翻译： 提供了制备西那卡塞，（R）-α-甲基-N- [3- [3-（三氟甲基）苯基]丙基] -1-萘甲烷胺的方法。
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