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公开(公告)号：US11166819B2
公开(公告)日：2021-11-09
申请号：US15899355
申请日：2018-02-19
发明人： Gerald B. Gollinger , William A. Maywald , Derrick Johnson , Brian S. Conklin , Ankita Bordoloi Gurunath , Da-Yu Chang
摘要： A heart valve sizer and sizer cover are provided for determining the size of a heart valve annulus. The valve sizer can include a handle, a shaft extending distally from the handle, a sizing element coupled to the distal end of the shaft, the sizing element being movable between a first retracted position and a second expanded position, and a sizer cover. The sizer cover can be formed from a continuous sheet of material configured to surround at least a portion of the sizing element of the heart valve sizer so as to guard against entanglement of the sizing element with structures of a human heart.
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公开(公告)号：US11154394B2
公开(公告)日：2021-10-26
申请号：US16270849
申请日：2019-02-08
发明人： Jessica Guttenberg , Da-Yu Chang , Derrick Johnson , Brian S. Conklin , Qinggang Zeng , Myron Howanec, Jr. , Grace Myong Kim
IPC分类号： A61F2/24
摘要： A prosthetic heart valve configured to replace a native heart valve and for post-implant expansion and having a valve-type indicator thereon visible from outside the body post-implant. The indicator communicates information about the valve, such as the size or orifice diameter of the valve, and/or that the valve has the capacity for post-implant expansion. The indicator can be an alphanumeric symbol or other symbol or combination of symbols that represent information about the characteristics of the valve such as the valve size. The capacity for post-implant expansion facilitates a valve-in-valve procedure, where the valve-type indicator conveys information to the surgeon about whether the implanted valve is suitable for the procedure and informs the choice of the secondary valve.
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公开(公告)号：US20210259841A1
公开(公告)日：2021-08-26
申请号：US17244435
申请日：2021-04-29
IPC分类号： A61F2/24
摘要： An articulating implant holder system for heart valve repair or replacement has an implant configured to be secured to a heart valve annulus, an implant holder secured to the implant, an articulating handle assembly comprising a handle, a swivel pivotably secured to the handle at a first location and a connector pivotably secured to the swivel at a second location, an actuating cable secured between the handle and the connector to cause the swivel to move from a first position to a second position, and a latch removably secured to the implant holder. A plurality of sizer heads are configured to correspond to different sizes of heart valve annuluses and each of the plurality of sizer heads has a latching feature. A latching feature of the swivel is configured to removably snap on to the latching feature of each of the plurality of sizer heads and is configured to permanently snap on to the latch.
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公开(公告)号：US10849752B2
公开(公告)日：2020-12-01
申请号：US16297187
申请日：2019-03-08
发明人： Brian S. Conklin
摘要： A method and device for anchoring a prosthetic heart valve or annuloplasty ring to a valve annulus in a heart and a method of implanting same is disclosed. The device can include a prosthetic valve or annuloplasty ring with one or more anchors configured to be threaded or otherwise passed underneath a native leaflet and/or subvalvular tissue to secure the device at the native annulus.
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公开(公告)号：US20200368014A1
公开(公告)日：2020-11-26
申请号：US16989826
申请日：2020-08-10
发明人： Brian S. Conklin
IPC分类号： A61F2/24
摘要： A prosthetic heart valve can include a valve frame having a wireform portion and a stent portion. The wireform and stent portions can be undetachably coupled together via a plurality of upright struts so as to form a one-piece prosthetic heart valve frame. Alternatively, a self-expanding wireform portion and a balloon-expandable stent portion can be coupled together via one or more leaflets and a subassembly having a flexible leaflet support stent and a sealing ring. The wireform portion can include cusps and commissures configured to support a plurality of leaflets. The prosthetic valve can be radially collapsible for minimally invasive and/or transcatheter delivery techniques. Disclosed embodiments can also provide flexion of the wireform portion (e.g., of the commissures) in response to physiologic pulsatile loading when the valve is implanted in a patient's native valve annulus. Methods of making and using prosthetic heart valves are also disclosed.
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公开(公告)号：US20200330226A1
公开(公告)日：2020-10-22
申请号：US16921901
申请日：2020-07-06
发明人： Hengchu Cao , Brian S. Conklin , Paul A. Schmidt , Grace Myong Kim , James A. Davidson , Hoa Trinh Tran , Kristy Luong Tam
IPC分类号： A61F2/24
摘要： Disclosed prosthetic valves can comprise a sewing ring configured to secure the valve to an implantation site. Some disclosed valves comprise a resiliently collapsible frame having a neutral configuration and a collapsed deployment configuration. Some disclosed frames can self-expand to the neutral configuration when released from the collapsed deployment configuration. Collapsing a disclosed valve can provide convenient access to the sewing ring, such as for securing the valve to the implantation site, as well as for the insertion of the valve through relatively small surgical incisions.
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公开(公告)号：US20200323633A1
公开(公告)日：2020-10-15
申请号：US16914255
申请日：2020-06-26
发明人： Brian S. Conklin , Qinggang Zeng
IPC分类号： A61F2/24
摘要： A hybrid prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be expanded post implant in order to receive and/or support an expandable prosthetic heart valve therein (a valve-in-valve procedure). The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander. An inflow stent frame is expandable for anchoring the valve in place, and may have an outflow end that is collapsible for delivery and expandable post-implant to facilitate a valve-in-valve procedure.
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公开(公告)号：US20190380835A1
公开(公告)日：2019-12-19
申请号：US16430334
申请日：2019-06-03
发明人： Sven Benjamin Iversen , Adam J. Yestrepsky , Amy E. Munnelly , Bin Tian , Danny Barrientos Baldo, JR. , Brian S. Conklin , Louis A. Campbell , John Richard Carpenter
摘要： A method for repairing a native valve of a patient during a non-open-heart procedure includes attaching two or more attachment members to the native valve. The method also includes applying a force to the two or more attachment members such that the two or more attachment members cause a cinching effect on at least a portion of the native valve. The method further includes securing the two or more attachment members with one or more anchor members such that the two or more attachment members maintain the cinching effect.
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公开(公告)号：USD867594S1
公开(公告)日：2019-11-19
申请号：US29579402
申请日：2016-09-29
设计人： Da-Yu Chang , Brian S. Conklin
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公开(公告)号：US10314706B2
公开(公告)日：2019-06-11
申请号：US15625801
申请日：2017-06-16
摘要： A cardiac implant system including a cardiac implant such as an annuloplasty ring, a prosthetic heart valve, or a valved conduit pre-assembled at the time of manufacture with devices for securing the implant to a heart valve annulus using knotless suture fasteners. The knotless suture fasteners may be embedded within a pliant sealing edge of the cardiac implant, or they may be positioned adjacent to the sealing edge. The knotless suture fasteners are spring-biased so as to grip onto annulus anchoring sutures pass to therethrough upon removal of a restraining device, such as a hypotube inserted within the suture fasteners. Guide tubes are assembled in line with the suture fasteners to permit introduction of suture snares that pass through the suture fasteners and through the sealing edge to facilitate capture of the pre-installed annulus anchoring sutures.
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