公开(公告)号：US08829000B2

公开(公告)日：2014-09-09

申请号：US13617683

申请日：2012-09-14

申请人： Makoto Okada ,  Shuichiro Sato ,  Kenji Kawade ,  Kotaro Gotanda ,  Atsushi Shinbo ,  Youichi Nakano ,  Hideo Kobayashi

发明人： Makoto Okada ,  Shuichiro Sato ,  Kenji Kawade ,  Kotaro Gotanda ,  Atsushi Shinbo ,  Youichi Nakano ,  Hideo Kobayashi

IPC分类号： A61K31/4985 ,  C07D487/04 ,  C07D487/14

CPC分类号： C07D487/04 ,  C07D487/14

摘要： The invention discloses quinoxaline derivatives or salts thereof having PDE9-inhibiting activity and being useful as treating agent of dysuria and the like, which are represented by the formula (I) in the formula, R1 and R2 each independently stands for hydrogen, halogen, alkyl, alkoxy, acyl, amino and the like, R3 stands for alkyl, aryl, saturated carbocyclic group, saturated heterocyclic group, acyl and the like, R4 stands for hydrogen, hydroxy, alkyl or amino, R5 and R8 each independently stands for hydrogen, halogen, alkyl, alkenyl, alkoxy, cyano or nitro, R6 and R7 each independently stands for hydrogen, halogen, alkyl, alkenyl, alkynyl, alkoxy, cyano, amino, carbocyclic group, heterocyclic group, COR9 or SO2R9, R9 stands for hydrogen, hydroxy, alkyl, amino, pyrrolidin-1-yl, piperidin-1-yl, pyperazin-1-yl or the like, X stands for S or O, and A1, A2 and A3 each independently stands for N or C.

摘要翻译： 本发明公开了具有PDE9抑制活性的喹喔啉衍生物或其盐，可用作式（I）所示的排尿困难等的治疗剂，R 1和R 2各自独立地表示氢，卤素，烷基 烷氧基，酰基，氨基等，R3代表烷基，芳基，饱和碳环基，饱和杂环基，酰基等，R4代表氢，羟基，烷基或氨基，R5和R8各自独立代表氢， 卤素，烷基，烯基，烷氧基，氰基或硝基，R6和R7各自独立地代表氢，卤素，烷基，烯基，炔基，烷氧基，氰基，氨基，碳环基，杂环基，COR9或SO2R9，R9代表氢， 羟基，烷基，氨基，吡咯烷-1-基，哌啶-1-基，哒嗪-1-基等，X表示S或O，并且，A1，A2和A3各自独立地表示N或C.

公开(公告)号：US07975291B2

公开(公告)日：2011-07-05

申请号：US11949719

申请日：2007-12-03

申请人： Makoto Amamiya ,  Satoshi Amamiya ,  Tadashige Iwao ,  Makoto Okada

发明人： Makoto Amamiya ,  Satoshi Amamiya ,  Tadashige Iwao ,  Makoto Okada

IPC分类号： G06F7/04 ,  G06F15/16 ,  G06F17/30 ,  H04L29/06 ,  G06F21/00 ,  G06F15/173

CPC分类号： H04L63/0209 ,  G06F21/6227

摘要： In the global information sharing and distributing service system, the public use of idle resources can be propelled and sufficient security can be guaranteed on the resources for private use. A node machine configuring an information network includes resources located in a private zone available to private use, resources located in a public zone for public service use, and a private resource security management unit for management of the security of the resources located in the private zone.

摘要翻译： 在全球信息共享和分配服务体系中，可以推动公共闲置资源的利用，并为私人资源提供足够的安全保障。 配置信息网络的节点机器包括位于私人区域中的资源，可用于私人使用的私人区域，位于公共区域中的资源用于公共服务使用，以及私人资源安全管理单元，用于管理位于私人区域中的资源的安全性 。

公开(公告)号：US07866504B2

公开(公告)日：2011-01-11

申请号：US11431622

申请日：2006-05-11

申请人： Makoto Okada ,  Hiroshi Zushi ,  Katsuhiro Katagiri

发明人： Makoto Okada ,  Hiroshi Zushi ,  Katsuhiro Katagiri

IPC分类号： B65D43/14 ,  B65D43/12 ,  B65D25/00

CPC分类号： B60N3/101 ,  B60R7/04

摘要： A storage apparatus includes a container body, a lid member with an arm, a shaft, an urging member, and a slot. The container body has a top opening. The lid member opens and closes the top opening of the container body, and is held swingably to the container body. The arm extends downward from the lid member. The shaft supports the arm pivotably to the container body, and is fitted into the slot so as to pivotably hold the arm. The urging member urges the lid member upward. The slot extends up-and-downward. Moreover, the container body further has a receiver. The receiver is brought into contact with the lid member so as to support the lid member when the pivotably-supporting shaft moves relatively within the slot so as to move the lid member downward. Therefore, the arm and pivotably-supporting shaft hardly deform because no excessive load acts onto them.

摘要翻译： 存储装置包括容器主体，具有臂的盖构件，轴，推动构件和狭槽。 容器主体具有顶部开口。 盖构件打开和关闭容器主体的顶部开口，并且可摆动地保持在容器主体上。 臂从盖构件向下延伸。 轴支撑臂可枢转地连接到容器主体，并且被装配到槽中以枢转地保持臂。 推动构件向上推动盖构件。 插槽向上和向下延伸。 此外，容器主体还具有接收器。 接收器与盖构件接触，以便当可枢转支撑的轴相对地在槽内移动时支撑盖构件，以使盖构件向下移动。 因此，臂和可枢转支撑的轴几乎不变形，因为没有过大的负载作用在它们上。

公开(公告)号：US07842331B2

公开(公告)日：2010-11-30

申请号：US11892217

申请日：2007-08-21

申请人： Eishin Yamakawa ,  Makoto Okada ,  Jun Fujii ,  Takako Yamauchi

发明人： Eishin Yamakawa ,  Makoto Okada ,  Jun Fujii ,  Takako Yamauchi

IPC分类号： B05D3/00

CPC分类号： G11B5/8408

摘要： A manufacturing method of a magnetic recording medium having a surface where a lubricating layer is provided, the manufacturing method includes the steps of: applying a lubricant so that the lubricating layer is formed; and inspecting the magnetic recording medium where the lubricating layer is formed; wherein the step of inspecting includes a first step of floating a magnetic head over the magnetic recording medium or sliding the magnetic head on a surface of the magnetic recording medium; a second step of adhering a medium facing surface of the magnetic head to a surface of a substrate for measuring, standing the medium facing surface of the magnetic head on the surface of the substrate for measuring, and transferring the lubricant from the medium facing surface of the magnetic head to the substrate for measuring; a third step of measuring an amount of the lubricant on the surface of the substrate for measuring; and a fourth step of determining whether the amount of the lubricant is proper.

摘要翻译： 一种具有设置有润滑层的表面的磁记录介质的制造方法，其制造方法包括以下步骤：涂布润滑剂以形成润滑层; 并检查形成润滑层的磁记录介质; 其中检查步骤包括将磁头浮在磁记录介质上或将磁头滑动在磁记录介质的表面上的第一步骤; 将磁头的面向中间的表面粘附到用于测量的基板的表面的第二步骤，用于测量在基板的表面上的磁头的介质相对表面，用于测量，并将润滑剂从面向介质的表面 磁头到基板进行测量; 测量用于测量的基板的表面上的润滑剂的量的第三步骤; 以及确定润滑剂的量是否适当的第四步骤。

公开(公告)号：US07735092B2

公开(公告)日：2010-06-08

申请号：US10652485

申请日：2003-09-02

申请人： Makoto Okada ,  Tadashige Iwao

发明人： Makoto Okada ,  Tadashige Iwao

IPC分类号： G06F3/00 ,  G06F9/44 ,  G06F9/46 ,  G06F13/00

CPC分类号： H04L29/06 ,  H04L67/40 ,  H04L67/42 ,  Y10S707/99942

摘要： An object cooperative network system for executing processing in cooperation between objects connected by a common communication path. Each of the objects includes a transmitting section to transmit messages that include predetermined information to the network system. In addition, each object includes a monitoring section to monitor the predetermined information of the transmitted messages, and a reaction table to indicate correspondence between the transmitted messages. Each of the objects sets information to which the object should respond in the monitoring section, and receives a message to execute processing by making reference to the reaction table when information to which the object should respond is detected.

摘要翻译： 一种用于通过公共通信路径连接的对象之间协作执行处理的对象协作网络系统。 每个对象包括发送部分，用于向网络系统发送包括预定信息的消息。 此外，每个对象包括监视所发送的消息的预定信息的监视部分和用于指示所发送的消息之间的对应关系的响应表。 每个对象在监视部分中设置对象应该响应的信息，并且当检测到对象应该响应的信息时，通过参考反应表来接收执行处理的消息。

公开(公告)号：US07589895B2

公开(公告)日：2009-09-15

申请号：US10574833

申请日：2004-10-05

申请人： Makoto Okada ,  Kayoko Fujimura

发明人： Makoto Okada ,  Kayoko Fujimura

IPC分类号： G02B5/18

CPC分类号： G11B7/1356 ,  G02B5/1809 ,  G11B7/1353 ,  G11B2007/0006

摘要： A polarizing element usable for two wavelengths in a predetermined wavelength region and having a simple structure. The polarizing element has a two-layer structure in which a grid pattern of a constant period Λ having a triangular cross-section is formed on a substrate and a film with a refractive index higher than that of the substrate is deposited on the grid pattern. When first and second wavelengths λ1, λ2 satisfy λ1

摘要翻译： 一种可用于预定波长区域中的两个波长且具有简单结构的偏振元件。 偏振元件具有两层结构，其中在基板上形成具有三角形横截面的恒定周期λ的栅格图案，并且将折射率高于基板的膜沉积在栅格图案上。 当第一和第二波长λ1，λ2满足λ1<λ2时，λcosθ0<λ1，其中θ0是网格表面上的入射角。 确定网格周期，网格高度和膜厚度，使得相对于第一波长λ1，TE偏振零级衍射光的反射效率为预定值或更大，并且TM的传输效率 极化零级衍射光是预定值以上，因此相对于波长λ2，TE偏振零级衍射光的透射效率为规定值以上，TM- 极化零级衍射光是预定值以上。

公开(公告)号：US20090203703A1

公开(公告)日：2009-08-13

申请号：US11922233

申请日：2006-06-13

申请人： Kotaro Gotanda ,  Atsushi Shinbo ,  Youichi Nakano ,  Hideo Kobayashi ,  Makoto Okada ,  Akira Asagarasu

发明人： Kotaro Gotanda ,  Atsushi Shinbo ,  Youichi Nakano ,  Hideo Kobayashi ,  Makoto Okada ,  Akira Asagarasu

IPC分类号： A61K31/4985 ,  C07D495/04 ,  A61K31/519

CPC分类号： C07D495/04

摘要： This invention provides thienopyrimidine derivatives of the formula, wherein R1 stands for hydrogen atom, an alkyl group or the like; R2 stands for a hydrogen atom, an alkyl or amino group or the like, R3 stands for an alkyl, alkenyl or alkylthio group or the like or a group Y—X—; or R2 and R3 may together form tetramethylene group; X standing for a direct bond or linking group such as CH2, CH(OH), S, O, NH; Y standing for a substituted or unsubstituted aromatic carbocycylic, aromatic heterocylic, cycloalkyl or saturated heterocyclic group or the like; Z stands for S or O, and n is 0 or an integer of 1 to 4, or salts thereof, which exhibit an inhibitory effect on PDE9, and are therefore useful for prevention or treatment of overactive bladder syndrome, pollakiuria, urinary incontinence, dysuria associated with prostatic hyperplasia, urolithiasis, Alzheimer's disease, chronic obstructive pulmonary disease, myocardial infarction, thrombosis, diabetes and the like.

摘要翻译： 本发明提供下式的噻吩并嘧啶衍生物，其中R1代表氢原子，烷基等; R2表示氢原子，烷基或氨基等，R3表示烷基，烯基或烷硫基等或Y-X-基团; 或者R 2和R 3可以一起形成四亚甲基; X代表直接键或连接基团如CH 2，CH（OH），S，O，NH; Y表示取代或未取代的芳族碳环，芳香杂环，环烷基或饱和杂环基等; Z代表S或O，n为0或1〜4的整数，或其盐，对PDE9具有抑制作用，因此可用于预防或治疗膀胱过度活动症，尿频尿失禁，排尿困难 与前列腺增生，尿石症，阿尔茨海默病，慢性阻塞性肺疾病，心肌梗死，血栓形成，糖尿病等相关。

公开(公告)号：US07520405B2

公开(公告)日：2009-04-21

申请号：US11600773

申请日：2006-11-17

申请人： Tomohiro Ishida ,  Makoto Okada ,  Katsuhiro Katagiri

发明人： Tomohiro Ishida ,  Makoto Okada ,  Katsuhiro Katagiri

IPC分类号： B65D25/00

CPC分类号： B60N3/106

摘要： A cup holder includes a holder body, an inner-peripheral-side supporting member, a first urging member, an outer-peripheral-side supporting member, and a second urging member. The holder body has an accommodation portion. The first urging member urges the inner-peripheral-side supporting member rotatably upward to a first datum position. The second urging member urges the outer-peripheral-side supporting member rotatably upward to a second datum position. The first rotary shaft-center of the inner-peripheral-side supporting member, which is located at the first datum position, being disposed at a position, which is displaced by a predetermined magnitude toward an imaginary center of the accommodation portion of the holder body with respect to the second rotary shaft-center of the outer-peripheral-side supporting member, which is located at the second datum position.

摘要翻译： 杯架包括保持器主体，内周侧支撑构件，第一施力构件，外周侧支撑构件和第二施力构件。 保持体具有容纳部。 第一推动构件将内周侧支撑构件可旋转地向上推动到第一基准位置。 第二推动构件将外周侧支撑构件可旋转地向上推动到第二基准位置。 位于第一基准位置的内周侧支撑构件的第一旋转轴心设置在朝向保持体的收容部的假想中心位移一定位置的位置 相对于位于第二基准位置的外周侧支撑构件的第二旋转轴中心。

公开(公告)号：US20090059416A1

公开(公告)日：2009-03-05

申请号：US12172730

申请日：2008-07-14

申请人： Makoto Okada ,  Eishin Yamakawa ,  Yoshihiro Mitobe

发明人： Makoto Okada ,  Eishin Yamakawa ,  Yoshihiro Mitobe

IPC分类号： G11B21/02 ,  G11B5/33

CPC分类号： G11B5/725 ,  G11B5/8408

摘要： According to an aspect of an embodiment, an storage device includes a storage medium having a substrate, a storage medium layer for storing information, a first lubricating layer on a first area of the storage medium layer, and a second lubricating layer on a second area of the storage medium, the second lubricating layer having a viscosity lower than the first lubricating layer. The storage device further comprises a head for writing information into the storage medium layer or reading information from the storage medium layer.

摘要翻译： 根据实施例的一个方面，一种存储装置包括具有基板的存储介质，用于存储信息的存储介质层，在存储介质层的第一区域上的第一润滑层和在第二区域上的第二润滑层 所述第二润滑层的粘度低于所述第一润滑层。 存储装置还包括用于将信息写入存储介质层或从存储介质层读取信息的头。

公开(公告)号：US20090053394A1

公开(公告)日：2009-02-26

申请号：US11892217

申请日：2007-08-21

申请人： Eishin Yamakawa ,  Makoto Okada ,  Jun Fujii ,  Takako Yamauchi

发明人： Eishin Yamakawa ,  Makoto Okada ,  Jun Fujii ,  Takako Yamauchi

IPC分类号： B05D3/00 ,  G01N33/00

CPC分类号： G11B5/8408

摘要： A manufacturing method of a magnetic recording medium having a surface where a lubricating layer is provided, the manufacturing method includes the steps of: applying a lubricant so that the lubricating layer is formed; and inspecting the magnetic recording medium where the lubricating layer is formed; wherein the step of inspecting includes a first step of floating a magnetic head over the magnetic recording medium or sliding the magnetic head on a surface of the magnetic recording medium; a second step of adhering a medium facing surface of the magnetic head to a surface of a substrate for measuring, standing the medium facing surface of the magnetic head on the surface of the substrate for measuring, and transferring the lubricant from the medium facing surface of the magnetic head to the substrate for measuring; a third step of measuring an amount of the lubricant on the surface of the substrate for measuring; and a fourth step of determining whether the amount of the lubricant is proper.

摘要翻译： 一种具有设置有润滑层的表面的磁记录介质的制造方法，其制造方法包括以下步骤：涂布润滑剂以形成润滑层; 并检查形成润滑层的磁记录介质; 其中检查步骤包括将磁头浮在磁记录介质上或将磁头滑动在磁记录介质的表面上的第一步骤; 将磁头的面向中间的表面粘附到用于测量的基板的表面的第二步骤，用于测量在基板的表面上的磁头的介质相对表面，用于测量，并将润滑剂从面向介质的表面 磁头到基板进行测量; 测量用于测量的基板的表面上的润滑剂的量的第三步骤; 以及确定润滑剂的量是否适当的第四步骤。