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公开(公告)号：US06890352B1
公开(公告)日：2005-05-10
申请号：US10149017
申请日：2000-11-09
申请人： Jan Lentell
发明人： Jan Lentell
CPC分类号： A61F2/2403
摘要： A vessel valve including a sleeve or ring having a central opening and openable and closeable flap elements intended to allow the flow of blood through the central opening in one direction, whereas the flap elements are designed as circle segments, and the sector angle is 360 ° n wherein n is a number of circle segments and is equal to 3, 4, 5 or 6, and wherein each flap element at its outer edge is pivotably connected to an inwardly directed flange on the inside of the ring so that in a closed position they co-operate to form a sealing body and in an open position they allow free passage of blood. The ring is composed of n sections, whose pair-wise juxtaposed ends form recesses in the flange accommodating hinge elements which are arranged in the middle of the outer edge of each of the flap elements and which with assembled sections are locked by undercutting; and a method for the manufacture of such vessel valve.
摘要翻译： 一种容器阀，包括具有中心开口和可打开和可开启的舌片元件的套筒或环，其旨在允许血液在一个方向上流过中心开口，而瓣片元件被设计为圆形段，并且扇形角度为<数学 id =“MATH-US-00001”num =“00001”>
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公开(公告)号：US20040122515A1
公开(公告)日：2004-06-24
申请号：US10717817
申请日：2003-11-20
发明人： Xi Chu
IPC分类号： A61F002/24
CPC分类号： A61F2/2403 , Y10T29/49405
摘要： The present invention relates to noval design of mechanical valve prostheses and manufacturing methods. A series of prosthetic valves with novel design and a unique manufacturing approach are disclosed. These devices possess unique designs and are made of nanostructurely engineered biomaterial. In addition, a novel manufacturing approach will be used to produce these devices because the convention technique is incapable of fabricating the devices due to the small size, design requirements and material properties restrain. Furthermore, it provides the convenience and thus low cost in manufacturing. The devices are particularly but not exclusively useful in human circulation system to restore the normal functions.
摘要翻译： 本发明涉及机械阀门假体的设计和制造方法。 公开了一系列具有新颖设计和独特制造方法的人工瓣膜。 这些设备具有独特的设计，并由纳米结构设计的生物材料制成。 另外，由于由于尺寸小，设计要求和材料特性的限制，常规技术无法制造器件，因此将使用新颖的制造方法来生产这些器件。 此外，它提供了制造方便和因此低的成本。 这些装置在人体循环系统中特别有用但不是专门用于恢复正常功能。
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公开(公告)号：US06730122B1
公开(公告)日：2004-05-04
申请号：US09724618
申请日：2000-11-28
申请人： Karl K. Pan , James R. Ringdal , Steven D. Kruse
发明人： Karl K. Pan , James R. Ringdal , Steven D. Kruse
IPC分类号： A61F224
CPC分类号： A61F2/2403
摘要： A prosthetic heart valve for replacing a native heart valve is provided and includes a generally circular heart valve body having an inner wall defining a lumen configured to allow blood flow therethrough. Occluders are configured to rotate about opposed occluder ends between an open position and a closed position. The minor radius arcs cooperate with the occluders to allow the occluders to block blood flow through lumen when in a closed position yet provide an increased lumen when the occluders are in an open position.
摘要翻译： 提供了用于替换原生心脏瓣膜的假体心脏瓣膜，并且包括大致圆形的心脏瓣膜体，其具有限定被配置为允许血液流过其中的内腔的内壁。 封堵器构造成在打开位置和关闭位置之间围绕相对的封堵器端旋转。 小半径弧与闭塞器配合以允许闭塞器在处于闭合位置时阻塞血液流过管腔，同时当闭塞器处于打开位置时提供增加的内腔。
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公开(公告)号：US06569197B2
公开(公告)日：2003-05-27
申请号：US09893227
申请日：2001-06-27
IPC分类号： A61F224
CPC分类号： A61F2/2403
摘要： The present invention relates to a heart valve prosthesis having an annular body with a pair of flanges, and a closing element in the form of two or three flaps mounted through bearings into the body's recesses with freedom to be rotated. The annular body has a constant height on a greater portion of a ring circle, and a number of ledges equal to that of the flaps. The ledges are provided with flap rotation limiters. The flaps have ascending and descending surfaces oriented to the direct and reverse flow of blood, a side edge and an edge for joining the other flap. The descending surface of a flap is flat and the ascending surface thereof is spherically concave. The flaps have the minimal thickness on an axis of symmetry at the joining edge. The axes of rotation of the three flap embodiment are arranged relative to each other at an angle of 60° thereby to form the sides of an equilateral triangle. For the valve with two flaps the flange facing the direct flow of blood is thickened. Recesses for bearings enter into the thickened flange with the recesses having a lateral cylindrical surface and a concave bottom.
摘要翻译： 本发明涉及一种心脏瓣膜假体，其具有带有一对凸缘的环形体，以及两个或三个翼片形式的闭合元件，其通过轴承安装到主体的凹部中，自由旋转。 环形体在环形圈的较大部分上具有恒定的高度，并且多个凸缘等于襟翼的凸缘。 凸缘设有挡板旋转限位器。 翼片具有定向为血液直接和反向流动的上升和下降表面，侧边缘和用于连接另一个皮瓣的边缘。 翼片的下降表面是平坦的，其上升的表面是球形的。 翼片在接合边缘处具有对称轴线上的最小厚度。 三个翼片实施例的旋转轴线相对于彼此以60°的角度布置，从而形成等边三角形的侧面。 对于具有两个襟翼的阀门，面向血液直接流动的法兰变厚。 轴承的凹槽进入加厚法兰，凹槽具有侧面圆柱形表面和凹形底部。
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公开(公告)号：US20020161432A1
公开(公告)日：2002-10-31
申请号：US10132440
申请日：2002-04-25
IPC分类号： A61F002/24
CPC分类号： A61F2/2409 , A61F2/2403
摘要： A mechanical heart valve prosthesis has a generally rectangular orifice and two leaflets that move between a closed position nearly perpendicular to blood flow and an open position nearly parallel to blood flow. Due to the uniform dimension of a rectangle, the leaflets are hinged at the periphery of the orifice, and present a single large central flow region to the blood when opened. The base provides several means of constraining the leaflet rotation during opening and closing.
摘要翻译： 机械心脏瓣膜假体具有大致矩形的孔口和两个小叶，其在几乎垂直于血流的关闭位置和几乎平行于血流的打开位置之间移动。 由于矩形的尺寸均匀，小叶在孔的周边铰接，并且当打开时呈现单个大的中央流动区域到血液。 底座提供了几种在打开和关闭期间约束小叶旋转的方法。
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公开(公告)号：US06432135B1
公开(公告)日：2002-08-13
申请号：US09579313
申请日：2000-05-25
IPC分类号： A61F206
CPC分类号： A61F2/2403 , Y10T137/7839 , Y10T137/7898 , Y10T137/7922
摘要： A rigid leaflet blood check valve uses a torsion wire suspension to suspend the leaflet. The leaflet is non-contacting with the housing. Complete washout of all valve parts in blood contact exists. This eliminates areas of blood stasis which exist in valves employing conventional pivot bearings. Relative motion, wear, and washout problems have been eliminated in the valve.
摘要翻译： 刚性单张止血阀使用扭力线悬挂悬挂传单。 传单与房屋非接触。 血液接触中所有阀门部件完全冲洗存在。 这消除了使用常规枢转轴承的阀门中存在的血瘀区域。 在阀门中已经消除了相对运动，磨损和冲洗问题。
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公开(公告)号：US06395025B1
公开(公告)日：2002-05-28
申请号：US09224149
申请日：1998-12-31
IPC分类号： A61F206
CPC分类号： A61F2/2403
摘要： Mechanical heart valve prostheses are disclosed that inherently reduce the probability of thrombus formation by minimizing blood flow disturbance, high shear stress, and stagnation. The pivot configuration includes a recess, preferably in the housing, that has a profile which promotes smooth blood flow.
摘要翻译： 公开了机械心脏瓣膜假体，其通过最小化血流紊乱，高剪切应力和停滞来固有地降低血栓形成的可能性。 枢轴构造包括优选在壳体中的凹部，其具有促进平滑血流的轮廓。
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公开(公告)号：US20010031972A1
公开(公告)日：2001-10-18
申请号：US09798827
申请日：2001-03-02
IPC分类号： A61B017/10
CPC分类号： A61F2/2427 , A61B17/068 , A61B17/072 , A61B17/1155 , A61B2017/00243 , A61B2017/07214 , A61F2/2403
摘要： A surgical stapler for securing a prosthetic heart valve within a patient is disclosed and generally includes a first cylindrical portion for carrying a staple assembly on a distal end thereof, a second cylindrical portion positioned concentrically about the first cylindrical portion and having a camming arm on a distal end thereof and a third cylindrical portion positioned concentrically about the second cylindrical portion and having an anvil flange on a distal end thereof, the camming arm configured to cam the staple assembly radially outward and drive the staple assembly distally such that a first leg of the staple assembly penetrates a cuff of the prosthetic heart valve and a second leg of the staple assembly pierces a portion of heart tissue surrounding the prosthetic heart valve to secure the valve. A method of installing a heart valve within a patient utilizing the surgical stapler is also disclosed.
摘要翻译： 公开了一种用于将假体心脏瓣膜固定在患者体内的手术吻合器，并且通常包括用于在其远端上承载缝合钉组件的第一圆柱形部分，与第一圆柱形部分同心地定位的第二圆柱形部分， 其远端和第三圆柱形部分，其围绕第二圆柱形部分同心地定位并且在其远端具有砧座凸缘，所述凸轮臂构造成径向向外凸轮订做钉组件，并使钉组件向远侧方向移动，使得第一腿部 钉组件穿透假体心脏瓣膜的袖带，并且钉组件的第二腿刺穿围绕假体心脏瓣膜的心脏组织的一部分以固定瓣膜。 还公开了使用外科缝合器在患者体内安装心脏瓣膜的方法。
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公开(公告)号：US06228112B1
公开(公告)日：2001-05-08
申请号：US09312686
申请日：1999-05-14
申请人： Jack Klootz , Brian W. Hummel
发明人： Jack Klootz , Brian W. Hummel
IPC分类号： A61F224
CPC分类号： A61F2/2403
摘要： A prosthesis for use in a human heart as a valve that reduces or eliminates blood stagnation, and therefore, the possibility of thrombosis while increasing available blood flow area through the artificial heart valve without using hinges which can become inoperable due to interaction with blood and human tissue. The artificial heart valve includes a supporting ring, a pair of radially-disposed supporting arms having specially designed and support heads of a particular shape and a pair of semi-circular valve plates that hang from the support arm and engage the support arm heads. The valve plates each include a specially designed slot that receives the support arm head which allows movement of each of the valve plates during operation of the valve to prevent accumulation of human tissue from blocking the operation of the valve. Also, the support ring aperture, in conjunction with the support ring and the mounting of the valve plates has a configuration that aids in blood flow through the valve thereby preventing stagnation and the possibility of thrombosis.
摘要翻译： 在人心脏中使用的假体作为减少或消除血液滞留的瓣膜，因此在通过人造心脏瓣膜增加可用的血液流通面积的同时可以产生血栓形成，而不使用由于与血液和人类相互作用而可能变得不可操作的铰链 组织。 人造心脏瓣膜包括支撑环，一对径向设置的支撑臂，其具有特别设计的特殊形状的支撑头和一对从支撑臂悬挂并与支撑臂头部接合的半圆形阀板。 阀板各自包括专门设计的狭槽，其容纳支撑臂头部，该支撑臂头部在阀的操作期间允许每个阀板的移动，以防止人体组织的积聚阻塞阀的操作。 此外，支撑环孔与支撑环结合并且阀板的安装具有帮助血液流过阀的构造，从而防止血栓停滞和血栓形成的可能性。
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80.发明授权Heart valve prosthesis having a pivot design for improving flow characteristics 有权心脏瓣膜假体具有用于改善流动特征的枢轴设计公开(公告)号：US06206918B1
公开(公告)日：2001-03-27
申请号：US09310801
申请日：1999-05-12
IPC分类号： A61F224
CPC分类号： A61F2/2403
摘要： A heart valve prosthesis having improved flow characteristics. A heart valve prosthesis includes a valve body and a pair of leaflet occluders. The valve body includes an interior surface that defines a central passage for blood flow. The pair of leaflet occluders are pivotably mounted in the passage via ears or tabs that are received in recesses formed in the interior surface that defines the central passage. The recesses are formed with sloped sidewalls to improve the blood flow therethrough. The recesses are also formed such that the leaflet occluder ears act against at least two surfaces that limit the motion of the leaflet occluder to provide a more stable movement that is less damaging to blood cells.
摘要翻译： 具有改善的流动特性的心脏瓣膜假体。 心脏瓣膜假体包括阀体和一对小叶闭塞器。 阀体包括限定用于血流的中心通道的内表面。 一对小叶封堵器通过耳部或突出部枢转地安装在通道中，该耳或接头被容纳在形成在限定中心通道的内表面中的凹部中。 这些凹部形成有倾斜的侧壁以改善通过其中的血液流动。 这些凹陷也形成为使得小叶闭塞器耳朵抵抗限制小叶闭塞器运动的至少两个表面，以提供对血细胞损伤较小的更稳定的运动。
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