公开(公告)号：US6061107A

公开(公告)日：2000-05-09

申请号：US852589

申请日：1997-05-07

申请人： Deng-Ke Yang ,  Zhijian Lu ,  J. William Doane

发明人： Deng-Ke Yang ,  Zhijian Lu ,  J. William Doane

IPC分类号： G02F1/1334 ,  G02F1/137 ,  G02F1/1333 ,  G02F1/1339

CPC分类号： G02F1/13718 ,  G02F1/1334

摘要： Polymer/cholesteric liquid crystal dispersions are provided in which the liquid crystal phase separated from the polymer matrix to form droplets. The cholesteric liquid crystals were positive dielectric anisotropic. At a zero field condition, the liquid crystal in the droplets was bistable, that is, the liquid crystal can be in either the reflecting planar state or the scattering focal conic state. When the liquid crystal 101 was in the planar texture, the helical axis of the liquid crystal was more or less perpendicular to the cell surface; colored light 105 was Bragg reflected. When the liquid crystal 101 was in the focal conic texture, the helical axis was more or less parallel to the cell surface, incident light was scattering 106 in the forward direction.

摘要翻译： 提供聚合物/胆甾型液晶分散体，其中液晶相与聚合物基质分离形成液滴。 胆固醇液晶呈正介电各向异性。 在零场条件下，液滴中的液晶是双稳态的，即液晶可以处于反射平面状态或散射焦锥状态。 当液晶101处于平面结构时，液晶的螺旋轴或多或少垂直于单元表面; 彩色灯105被布拉格反射。 当液晶101处于焦锥状纹理时，螺旋轴或多或少地平行于单元表面，入射光向前方散射106。

公开(公告)号：US5731317A

公开(公告)日：1998-03-24

申请号：US401849

申请日：1995-03-10

申请人： Zhijian Lu ,  Arthur A. Patchett ,  James R. Tata

发明人： Zhijian Lu ,  Arthur A. Patchett ,  James R. Tata

IPC分类号： C07D451/02 ,  A61K31/445 ,  A61K31/46

CPC分类号： C07D451/00 ,  C07D451/02

摘要： The present invention is directed to certain novel compounds identified as bridged piperidines of the general structural formula: ##STR1## wherein R.sup.1, R.sup.1a, R.sup.2a, R.sup.3, R.sup.3a,R.sup.4, R.sup.5, A, X, and Y are as defined herein. These compounds promote the release of growth hormone in humans and animals. This property can be utilized to promote the growth of food animals to render the production of edible meat products more efficient, and in humans, to treat physiological or medical conditions characterized by a deficiency in growth hormone secretion, such as short stature in growth hormone deficient children, and to treat medical conditions which are improved by the anabolic effects of growth hormone. Growth hormone releasing compositions containing such compounds as the active ingredient thereof are also disclosed.

摘要翻译： 本发明涉及确定为通式结构式的桥连哌啶的某些新化合物：其中R1，R1a，R2a，R3，R3a，R4，R5，A，X和Y如本文所定义。 这些化合物促进人和动物中生长激素的释放。 这种性质可以用于促进食用动物的生长，使食用肉制品的生产更有效，并且在人类中，用于治疗以生长激素分泌不足为特征的生理或医学病症，例如生长激素缺乏的身材矮小 儿童，并且治疗通过生长激素的合成代谢作用改善的医疗状况。 还公开了含有这些化合物作为其活性成分的生长激素释放组合物。