公开(公告)号：US07745795B2

公开(公告)日：2010-06-29

申请号：US12045934

申请日：2008-03-11

申请人： Katsutoshi Tsuchiya ,  Hiroshi Kitaguchi ,  Kazuma Yokoi ,  Kikuo Umegaki ,  Kensuke Amemiya ,  Yuuichirou Ueno ,  Norihito Yanagita ,  Shinichi Kojima

发明人： Katsutoshi Tsuchiya ,  Hiroshi Kitaguchi ,  Kazuma Yokoi ,  Kikuo Umegaki ,  Kensuke Amemiya ,  Yuuichirou Ueno ,  Norihito Yanagita ,  Shinichi Kojima

IPC分类号： G01T1/161

CPC分类号： G01T1/2928

摘要： In a gamma camera, a plurality of radiation detector elements having a rod-shaped first electrode, a semiconductor device surrounds the first electrode to contact with it for entering a radiation, and a second electrode provided for the side surface of the semiconductor device are detachably attached to a holding member. The holding member has a first electrode contact portion contacted with the first electrode and a second electrode contact portion contacted with the second electrode. A collimator in which a plurality of radiation paths provided corresponding to the plurality of radiation detector elements are formed is arranged on the radiation entering side of the plurality of radiation detector elements. A γ-ray detection signal outputted from the first electrode contact portion is sent to a signal processing integrated circuit. A high voltage is applied to the second electrode via the second electrode contact portion.

摘要翻译： 在伽马照相机中，具有杆状第一电极的多个辐射检测器元件，包围第一电极以与其接触以进入辐射的半导体器件以及为半导体器件的侧表面设置的第二电极是可拆卸的 附着于握持构件。 保持构件具有与第一电极接触的第一电极接触部分和与第二电极接触的第二电极接触部分。 在多个辐射检测器元件的辐射入射侧设置准直器，其中形成有与多个辐射检测器元件对应的多个辐射路径。 从第一电极接触部分输出的γ射线检测信号被发送到信号处理集成电路。 经由第二电极接触部分向第二电极施加高电压。

公开(公告)号：US07683338B2

公开(公告)日：2010-03-23

申请号：US10874359

申请日：2004-06-24

申请人： Yuuichirou Ueno ,  Hiroshi Kitaguchi ,  Katsutoshi Tsuchiya ,  Kensuke Amemiya ,  Kazuma Yokoi ,  Shinichi Kojima ,  Norihito Yanagita ,  Takafumi Ishitsu

发明人： Yuuichirou Ueno ,  Hiroshi Kitaguchi ,  Katsutoshi Tsuchiya ,  Kensuke Amemiya ,  Kazuma Yokoi ,  Shinichi Kojima ,  Norihito Yanagita ,  Takafumi Ishitsu

IPC分类号： G01T1/24

CPC分类号： A61B6/032 ,  A61B6/037 ,  G01T1/1611 ,  G01T1/1614 ,  G01T1/243 ,  G01T1/249 ,  G01T1/2985 ,  H01L31/1085 ,  H01L31/119

摘要： The radiological imaging system which can improve an energy resolution and perform a diagnosis with high accuracy includes a bed for carrying an examinee H, first and second imaging apparatuses and disposed along the longitudinal direction of the bed. The first imaging apparatus has a plurality of semiconductor radiation detectors for detecting γ-rays emitted from the examinee H, arranged around the bed, the second imaging apparatus has an X-ray source for emitting X-rays to the examinee H and a radiation detector for detecting X-rays which have been emitted from the X-ray source and passed through the examinee H, and the bed is shared by the first imaging apparatus and the second imaging apparatus.

摘要翻译： 能够高精度地提高能量分辨率和进行诊断的放射线成像系统包括：用于携带被检体H的床，第一和第二成像装置，沿着床的长度方向配置。 第一成像装置具有多个半导体辐射检测器，用于检测从被检体H发射的γ射线，布置在床周围，第二成像装置具有用于向受检者H发射X射线的X射线源和放射线检测器 用于检测从X射线源发射并通过受检者H的X射线，并且床由第一成像装置和第二成像装置共享。

公开(公告)号：US07535008B2

公开(公告)日：2009-05-19

申请号：US11836448

申请日：2007-08-09

申请人： Katsutoshi Tsuchiya ,  Tsuneaki Kawaguchi ,  Yuichi Morimoto ,  Masatoshi Tanaka ,  Hiroshi Kitaguchi ,  Kazuma Yokoi ,  Takafumi Ishitsu ,  Naoki Kubo ,  Nagara Tamaki

发明人： Katsutoshi Tsuchiya ,  Tsuneaki Kawaguchi ,  Yuichi Morimoto ,  Masatoshi Tanaka ,  Hiroshi Kitaguchi ,  Kazuma Yokoi ,  Takafumi Ishitsu ,  Naoki Kubo ,  Nagara Tamaki

IPC分类号： G01T1/166

CPC分类号： G01T1/2928

摘要： A radiation imaging system is configured by a collimator 30A including a detector 21 with a discrete detection pixel corresponding with a pixel and a plurality of radiation passages 31 and looks into a plurality of detectors 21 through one radiation passage 31 to set a step width of rotation around a rotation center axis X1 only for an angle θp made by lines provided by connecting a center detector 21 of the radiation passage 31 and the adjacent two detectors 21. In the case of generating a flat plane projection image for one direction, radio-graphing is carried out on a projection image in a plurality of predetermined angle positions (−θp, 0, +θp) in the circumferential direction of the rotation center axis X1 and thereby one plane projection image is obtained.

摘要翻译： 辐射成像系统由包括具有与像素对应的离散检测像素和多个辐射通道31的检测器21的准直仪30A配置，并且通过一个辐射通道31查看多个检测器21，以设置旋转的台阶宽度 围绕旋转中心轴线X1，仅对于通过连接辐射通道31的中心检测器21和相邻的两个检测器21而提供的线所形成的角度。在生成一个方向的平面投影图像的情况下，无线电绘图 在旋转中心轴X1的圆周方向上的多个预定角度位置（-thetap，0，+ thetap）中的投影图像上进行，从而获得一个平面投影图像。

公开(公告)号：US20080283760A1

公开(公告)日：2008-11-20

申请号：US12045934

申请日：2008-03-11

申请人： Katsutoshi TSUCHIYA ,  Hiroshi Kitaguchi ,  Kazuma Yokoi ,  Kikuo Umegaki ,  Kensuke Amemiya ,  Yuuichirou Ueno ,  Norihito Yanagita ,  Shinichi Kojima

发明人： Katsutoshi TSUCHIYA ,  Hiroshi Kitaguchi ,  Kazuma Yokoi ,  Kikuo Umegaki ,  Kensuke Amemiya ,  Yuuichirou Ueno ,  Norihito Yanagita ,  Shinichi Kojima

IPC分类号： G01T1/161

CPC分类号： G01T1/2928

摘要： In a gamma camera, a plurality of radiation detector elements having a rod-shaped first electrode, a semiconductor device surrounds the first electrode to contact with it for entering a radiation, and a second electrode provided for the side surface of the semiconductor device are detachably attached to a holding member. The holding member has a first electrode contact portion contacted with the first electrode and a second electrode contact portion contacted with the second electrode. A collimator in which a plurality of radiation paths provided corresponding to the plurality of radiation detector elements are formed is arranged on the radiation entering side of the plurality of radiation detector elements. A γ-ray detection signal outputted from the first electrode contact portion is sent to a signal processing integrated circuit. A high voltage is applied to the second electrode via the second electrode contact portion.

摘要翻译： 在伽马照相机中，具有棒状第一电极的多个辐射检测器元件，包围第一电极以与其接触以进入辐射的半导体器件以及为半导体器件的侧表面设置的第二电极是可拆卸的 附着于握持构件。 保持构件具有与第一电极接触的第一电极接触部分和与第二电极接触的第二电极接触部分。 在多个辐射检测器元件的辐射入射侧设置准直器，其中形成有与多个辐射检测器元件对应的多个辐射路径。 从第一电极接触部分输出的伽马射线检测信号被发送到信号处理集成电路。 经由第二电极接触部分向第二电极施加高电压。

公开(公告)号：US20080078937A1

公开(公告)日：2008-04-03

申请号：US11836448

申请日：2007-08-09

申请人： Katsutoshi TSUCHIYA ,  Tsuneaki Kawaguchi ,  Yuichi Morimoto ,  Masatoshi Tanaka ,  Hiroshi Kitaguchi ,  Kazuma Yokoi ,  Takafumi Ishitsu

发明人： Katsutoshi TSUCHIYA ,  Tsuneaki Kawaguchi ,  Yuichi Morimoto ,  Masatoshi Tanaka ,  Hiroshi Kitaguchi ,  Kazuma Yokoi ,  Takafumi Ishitsu

IPC分类号： G01T1/166

CPC分类号： G01T1/2928

摘要： A radiation imaging system is configured by a collimator 30A including a detector 21 with a discrete detection pixel corresponding with a pixel and a plurality of radiation passages 31 and looks into a plurality of detectors 21 through one radiation passage 31 to set a step width of rotation around a rotation center axis X1 only for an angle θp made by lines provided by connecting a center detector 21 of the radiation passage 31 and the adjacent two detectors 21. In the case of generating a flat plane projection image for one direction, radio-graphing is carried out on a projection image in a plurality of predetermined angle positions (−θp, 0, +θp) in the circumferential direction of the rotation center axis X1 and thereby one plane projection image is obtained.

摘要翻译： 放射线成像系统由包括具有与像素对应的离散检测像素的检测器21和多个辐射通道31的准直仪30A配置，并且通过一个辐射通道31查看多个检测器21，以设定步骤宽度 仅通过连接辐射通道31的中心检测器21和相邻的两个检测器21所提供的线所产生的角度来绕旋转中心轴线X 1旋转。 在为一个方向生成平面投影图像的情况下，在旋转中心轴X的圆周方向上的多个预定角度位置（-thetap，0，+ thetap）中的投影图像上进行放射线图 1，从而获得一个平面投影图像。

公开(公告)号：US20080029705A1

公开(公告)日：2008-02-07

申请号：US11822031

申请日：2007-06-29

申请人： Katsutoshi Tsuchiya ,  Hiroshi Kitaguchi ,  Yuichi Morimoto ,  Shinya Kominami ,  Kazuma Yokoi ,  Tsuneaki Kawaguchi ,  Masatoshi Tanaka ,  Takafumi Ishitsu

发明人： Katsutoshi Tsuchiya ,  Hiroshi Kitaguchi ,  Yuichi Morimoto ,  Shinya Kominami ,  Kazuma Yokoi ,  Tsuneaki Kawaguchi ,  Masatoshi Tanaka ,  Takafumi Ishitsu

IPC分类号： G21K1/02

CPC分类号： G01T1/1648 ,  A61B6/037

摘要： Disclosed herein is a radiation imaging apparatus and radiation-imaging-apparatus-based nuclear medicine diagnosis apparatus having a collimator in which a plurality of rectangular through-holes are arranged in a grid pattern and separated by septa is rotated through a predetermined angle as viewed from above in relation to the layout of a plurality of rectangular detectors that are arranged in a grid pattern. The predetermined angle ranges from 20 to 70 degree and more preferably from 30 deg to 60 deg. With this configuration, the influence of sensitivity variations (moire patterns) that are included in an image picked up due to interference with a collimator when pixel type detectors are used is eliminated.

公开(公告)号：US07297958B2

公开(公告)日：2007-11-20

申请号：US10270151

申请日：2002-10-15

申请人： Shinichi Kojima ,  Takashi Okazaki ,  Yuuichirou Ueno ,  Kikuo Umegaki ,  Kensuke Amemiya ,  Kazuhiro Takeuchi ,  Hiroshi Kitaguchi ,  Kazuma Yokoi ,  Norihito Yanagita

发明人： Shinichi Kojima ,  Takashi Okazaki ,  Yuuichirou Ueno ,  Kikuo Umegaki ,  Kensuke Amemiya ,  Kazuhiro Takeuchi ,  Hiroshi Kitaguchi ,  Kazuma Yokoi ,  Norihito Yanagita

IPC分类号： G01T1/24 ,  G01T1/161 ,  G01T1/172 ,  G01T1/29 ,  H05G1/64

CPC分类号： G01T1/1611 ,  A61B6/037 ,  A61B6/4241 ,  A61B6/5235 ,  G01N23/046 ,  G01N2223/419 ,  G01N2223/612 ,  G01T1/2985 ,  Y10S378/901

摘要： A radiological imaging apparatus of the present invention comprises an image pickup device and a medical examinee holding device that is provided with a bed. The image pickup device includes a large number of radiation detectors and radiation detector support plates. A large number of radiation detectors are mounted around the circumference of a through-hole and arranged in the axial direction of the through-hole. The radiation detectors are arranged in three layers formed radially with respect to the center of the through-hole and mounted on the lateral surfaces of the radiation detector support plates. Since the radiation detectors are not only arranged in the axial direction and circumferential direction of the through-hole but also arrayed in the radial direction, it is possible to obtain accurate information about a γ-ray arrival position in the radial direction of the through-hole (the positional information about a radiation detector from which a γ-ray image pickup signal is output). The use of accurate information about γ-ray arrival increases the tomogram accuracy. As a result, the present invention enhances the tomogram accuracy, that is, the PET examination accuracy.

摘要翻译： 本发明的放射学成像装置包括：图像拾取装置和设有床的医疗检查者保持装置。 图像拾取装置包括大量的辐射检测器和辐射检测器支撑板。 大量的辐射探测器安装在通孔的圆周周围并沿通孔的轴向布置。 辐射检测器被布置成相对于通孔的中心径向形成的三层，并且安装在辐射检测器支撑板的侧表面上。 由于辐射检测器不仅沿着通孔的轴向方向和圆周方向布置，而且沿径向排列，可以获得关于通孔的径向方向上的伽马射线到达位置的准确信息， （关于从其输出伽马射线摄像信号的放射线检测器的位置信息）。 使用关于伽马射线到达的准确信息增加了断层图像的准确性。 结果，本发明增强了断层图像精度，即PET检查精度。

公开(公告)号：US07264790B2

公开(公告)日：2007-09-04

申请号：US10487319

申请日：2002-08-22

申请人： Kazunobu Takahashi ,  Hiroshi Kitaguchi ,  Kazuhiro Aikawa

发明人： Kazunobu Takahashi ,  Hiroshi Kitaguchi ,  Kazuhiro Aikawa

IPC分类号： A61K49/00 ,  C07C53/00 ,  C07C57/00 ,  C07C59/00 ,  C08G63/48 ,  A61K49/04

CPC分类号： C07C233/83 ,  A61K49/0433 ,  A61K49/0466 ,  C07C69/66 ,  C07C69/712 ,  C07C69/736 ,  C07C233/18 ,  C07C237/20 ,  C07C323/52

摘要： A compound represented by the following general formula (I) or a salt thereof: wherein Ar1 and Ar2 independently represent a substituted or unsubstituted aryl group having at least one iodine atom as a substituent; L1 and L2 independently represent a divalent bridging group of which main chain consists of 7 or more atoms at least one of which is a heteroatom; and X represents —CH(OH)— or —CO—, which is suitable for an iodine-containing contrast medium containing liposomes.

摘要翻译： 由以下通式（I）表示的化合物或其盐：其中Ar 1和Ar 2独立地表示具有至少一个碘原子的取代或未取代的芳基 作为取代基; L 1和L 2独立地表示二价桥连基团，其主链由7个或更多个原子组成，其中至少一个是杂原子; X表示-CH（OH） - 或-CO-，适用于含有脂质体的含碘造影剂。

公开(公告)号：US07218701B2

公开(公告)日：2007-05-15

申请号：US11370915

申请日：2006-03-09

申请人： Yuuichirou Ueno ,  Hiroshi Kitaguchi ,  Kensuke Amemiya ,  Kikuo Umegaki ,  Norihito Yanagita ,  Shinichi Kojima ,  Kazuma Yokoi

发明人： Yuuichirou Ueno ,  Hiroshi Kitaguchi ,  Kensuke Amemiya ,  Kikuo Umegaki ,  Norihito Yanagita ,  Shinichi Kojima ,  Kazuma Yokoi

IPC分类号： A61B6/00

CPC分类号： G01T1/2985 ,  A61B6/032 ,  A61B6/037 ,  A61B6/5235 ,  G01T1/1615 ,  G01T1/1644

摘要： The image pickup apparatus of the radiological imaging apparatus of the present invention includes many detector units, a ring-shaped detector support member and an X-ray source circumferential transport apparatus. Each of the detector units is attached to the detector support section in a detachable manner. A plurality of radiation detectors provided for the detector units are arranged in three layers in the radius direction of the detector support member and in three columns in the axial direction of the detector support member. Since the radiation detectors are arranged in three layers in the radius direction, it is possible to recognize the detection position of radiation in the radius direction in detail. Furthermore, since the detector units are attached in a detachable manner, it is easy to replace damaged radiation detectors.

摘要翻译： 本发明的放射线摄影装置的摄像装置具备许多探测器单元，环形探测器支撑构件和X射线源圆周传送装置。 每个检测器单元以可拆卸的方式附接到检测器支撑部分。 为检测器单元设置的多个辐射检测器在检测器支撑构件的半径方向上布置成三层，并且沿检测器支撑构件的轴向方向布置成三列。 由于辐射检测器在半径方向上布置成三层，因此可以详细地识别辐射在半径方向上的检测位置。 此外，由于检测器单元以可拆卸的方式附接，所以易于替换损坏的辐射探测器。

公开(公告)号：US07183557B2

公开(公告)日：2007-02-27

申请号：US11257127

申请日：2005-10-25

申请人： Kazuma Yokoi ,  Hiroshi Kitaguchi ,  Takafumi Ishitsu ,  Naoyuki Yamada ,  Kensuke Amemiya ,  Yuuichirou Ueno ,  Katsutoshi Tsuchiya ,  Norihito Yanagita

发明人： Kazuma Yokoi ,  Hiroshi Kitaguchi ,  Takafumi Ishitsu ,  Naoyuki Yamada ,  Kensuke Amemiya ,  Yuuichirou Ueno ,  Katsutoshi Tsuchiya ,  Norihito Yanagita

IPC分类号： G01T1/24

CPC分类号： G01T1/249 ,  G01T1/243 ,  H01L27/14658 ,  H01R12/88

摘要： A radiological imaging apparatus allowing semiconductor radiation detectors to be easily replaced with new ones and densely arranged. Terminals (31cjk) and (33cjk) are provided on a bottom surface of a detector aggregate (40mn) including a plurality of semiconductor radiation detectors (1); the terminals is connected to electrodes (3 and 4) of the detectors (1). A plurality of zero insertion force connectors (56) are provided on a connecting device (33jk) installed on a support substrate (32h). The terminals (31cjk and 33cjk) are detachably attached to the zero insertion force connectors (56) to mount the detector aggregates (40mn) that are the semiconductor radiation detectors (1), on the support substrate (32h). When the detector aggregates (40mn) are attached to the zero insertion force connectors (56), since no frictional force acts on the terminals, the size of the gap between the detector aggregates (40mn) is reduced.