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公开(公告)号：US20110154888A1
公开(公告)日：2011-06-30
申请号：US12737999
申请日：2009-09-17
IPC分类号： G01N11/02
CPC分类号： G01N35/08 , G01F1/704 , G01F1/7086 , G01N2015/1006 , G01N2015/105 , G01N2015/1495
摘要： The present invention relates to an analysis apparatus 1 comprising a resistive body 2 for giving a travel resistance to a sample, and power sources 33, 54 for giving power to cause the sample to pass through the resistive body 2. The power sources 33, 54 include a pressurizing mechanism 33 arranged at an upstream side of the resistive body 2 and a pressure-reduction mechanism 54 arranged at a downstream side of the resistive body. The pressurizing mechanism 33 and the pressure-reduction mechanism 54 are each a tube pump, for example. The resistive body 2 is provided with a plurality of minute fluid channels, for example.
摘要翻译： 本发明涉及一种分析装置1，其包括用于赋予样品行进阻力的电阻体2，以及用于给予试样通过电阻体2的电力的电源33,54。电源33,54 包括布置在电阻体2的上游侧的加压机构33和布置在电阻体的下游侧的减压机构54。 加压机构33和减压机构54例如都是管式泵。 电阻体2例如具有多个微小的流体通道。
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公开(公告)号：USD596322S1
公开(公告)日：2009-07-14
申请号：US29309635
申请日：2008-09-16
申请人： Daisuke Takahashi , Valerio Aiello
设计人： Daisuke Takahashi , Valerio Aiello
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公开(公告)号：US20090171084A1
公开(公告)日：2009-07-02
申请号：US12338242
申请日：2008-12-18
申请人： Daisuke Takahashi , Kunisuke Izawa
发明人： Daisuke Takahashi , Kunisuke Izawa
IPC分类号： C07D239/52
CPC分类号： C07D239/47
摘要： Aminopyrimidine compounds represented by formula (3) may be efficiently prepared by reacting an azlactone compound represented by formula (1) with an amidine compound represented by formula (2) or a salt thereof: wherein R1, R2 and M are as defined in the specification.
摘要翻译： 由式（3）表示的氨基嘧啶化合物可以通过使式（1）表示的吖内酯化合物与式（2）表示的脒化合物或其盐反应来有效制备：其中R1，R2和M如说明书中所定义 。
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公开(公告)号：US07491822B2
公开(公告)日：2009-02-17
申请号：US11081631
申请日：2005-03-17
申请人： Daisuke Takahashi , Kunisuke Izawa
发明人： Daisuke Takahashi , Kunisuke Izawa
IPC分类号： C07D239/02
CPC分类号： C07D239/47
摘要： Aminopyrimidine compounds represented by formula (3) may be efficiently prepared by reacting an azlactone compound represented by formula (1) with an amidine compound represented by formula (2) or a salt thereof: wherein R1, R2 and M are as defined in the specification.
摘要翻译： 由式（3）表示的氨基嘧啶化合物可以通过使式（1）表示的吖内酯化合物与式（2）表示的脒化合物或其盐反应来有效制备：其中R1，R2和M如说明书中所定义 。
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公开(公告)号：USD582317S1
公开(公告)日：2008-12-09
申请号：US29290150
申请日：2007-10-25
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公开(公告)号：US07392103B2
公开(公告)日：2008-06-24
申请号：US10898725
申请日：2004-07-23
申请人： Daisuke Takahashi
发明人： Daisuke Takahashi
IPC分类号： G06F17/00
CPC分类号： H04H60/04
摘要： In an audio signal processing device which processes audio signals and outputs the audio signals, on the recalling setting data representing a setting status of the device, protection setting defining a group which is not recalled at the time of recalling the setting data among a plurality of groups constituting the setting data is accepted as a local setting for each setting data and a global setting common to each setting data separately, and an enabled or disabled setting of the protection setting for the setting data is accepted for each setting data, wherein when the setting data is recalled, the recall is performed in accordance with the local protection setting when the protection setting for the setting data is enabled, and in accordance with the global protection setting when the protection setting for the setting data is disabled.
摘要翻译： 在处理音频信号并输出音频信号的音频信号处理设备中，对表示设备的设置状态的调用设置数据，保护设置定义在多个调用中调用设置数据之后未调用的组 构成设置数据的组被接受为用于每个设置数据的本地设置和每个设置数据共同的全局设置，并且对于每个设置数据接受用于设置数据的保护设置的启用或禁用设置，其中当 设置数据被调用时，当设置数据的保护设置被使能时，根据设置数据的保护设置被禁用时根据全局保护设置，根据本地保护设置执行调用。
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公开(公告)号：US07345164B2
公开(公告)日：2008-03-18
申请号：US10829950
申请日：2004-04-23
申请人： Daisuke Takahashi , Kunisuke Izawa
发明人： Daisuke Takahashi , Kunisuke Izawa
IPC分类号： C07H19/067 , C07H19/167
摘要： A production method for conveniently producing a 5′-acyloxynucleoside compound shown by the formula [A] in a good yield while suppressing formation of by-products, including subjecting a 2′,3′,5′-triacyloxynucleoside compound represented by the formula [I] to selective deacylation in an alcohol represented by the formula [II] using a base selected from the group consisting of alkali metal hydroxide, alkali metal alkoxide and alkali metal carbonate: wherein each symbol in the formula is as defined in the specification.
摘要翻译： 包括使式[A]所示的2'，3'，5'-三酰氧基核苷化合物抑制副产物的形成，以良好的产率方便地制备式[A]所示的5'-酰氧基核苷化合物的方法， I]使用选自碱金属氢氧化物，碱金属醇盐和碱金属碳酸盐的碱选自式[II]表示的醇中的选择性脱酰基：其中式中的每个符号如说明书中所定义。
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公开(公告)号：US20080015353A1
公开(公告)日：2008-01-17
申请号：US11832769
申请日：2007-08-02
申请人： Daisuke Takahashi , Kunisuke Izawa
发明人： Daisuke Takahashi , Kunisuke Izawa
IPC分类号： C07D239/02 , C07D403/02
CPC分类号： C07D239/38 , C07C45/68 , C07C45/70 , C07C49/255
摘要： Compound (II) is reacted with formate in the presence of an alkali metal alkoxide and the like to give compound (III); then this is reacted with compound (IVa) or compound (IVb) to give compound (V); then this is reacted with compound (VI) to give compound (VII); and then this is deprotected to give compound (I). The present invention provides an industrially advantageous production method of a 4-acetylpyrimidine compound useful as a synthetic intermediate for a pharmaceutical product: wherein X is a methylthio group and the like, R1 is a lower alkyl group and the like, R2 is a lower alkyl group optionally having substituent(s) and the like, M is an alkali metal and X1 is a halogen atom.
摘要翻译： 在碱金属醇盐等存在下使化合物（II）与甲酸酯反应，得到化合物（III）; 然后使其与化合物（IVa）或化合物（IVb）反应，得到化合物（V）; 然后使其与化合物（VI）反应，得到化合物（VII）; 然后将其脱保护，得到化合物（I）。 本发明提供了可用作药物合成中间体的4-乙酰基嘧啶化合物的工业上有利的制备方法：其中X是甲硫基等，R 1是低级烷基， R 2是任选具有取代基等的低级烷基，M是碱金属，X 1是卤素原子。
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公开(公告)号：US07208622B2
公开(公告)日：2007-04-24
申请号：US10418105
申请日：2003-04-18
IPC分类号： C07C229/00
CPC分类号： C07C231/02 , C07C231/24 , C07C2601/14 , C07C233/63
摘要： There is provided methods for producing nateglinide crystals, which comprises the steps of adding an acid(s) to a reaction mixture containing nateglinide to make it acidic, the reaction mixture being obtained by reacting trans-4-isopropylcyclohexylcarbonyl chloride with D-phenylalanine in a mixed solvent of ketone solvent and water in the presence of an alkali; and then adjusting the temperature of the mixture to 58° C. to 72° C. and the concentration of ketone solvent to more than 8 wt % and less than 22 wt % to conduct precipitation of nateglinide crystals. This producing method is the industrially beneficial methods for crystallization of nateglinide.
摘要翻译： 提供了那格列奈晶体的制备方法，其包括以下步骤：向含有那格列奈的反应混合物中加入酸以使其呈酸性，反应混合物通过反式-4-异丙基环己基羰基氯与D-苯丙氨酸反应获得 酮溶剂和水的混合溶剂在碱的存在下; 然后将混合物的温度调节至58℃至72℃，酮溶剂的浓度大于8重量％且小于22重量％，以进行那格列奈晶体的沉淀。 这种生产方法是奈格列奈结晶的工业上有益的方法。
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公开(公告)号：US07148313B2
公开(公告)日：2006-12-12
申请号：US10885739
申请日：2004-07-08
申请人： Takashi Koga , Daisuke Takahashi , Mitsuhiro Takeo
发明人： Takashi Koga , Daisuke Takahashi , Mitsuhiro Takeo
IPC分类号： C08G63/00
CPC分类号： C08K5/103 , C08K5/0008 , C08K5/3437 , C08L69/00
摘要： A polycarbonate resin composition comprising 100 parts by weight of a polycarbonate resin (component A), 0.01 to 10 parts by weight of at least one ultraviolet light absorber (component B) selected from the group of a specific cyclic imino ester, and 0.01 to 1 part by weight of a fatty acid ester compound (component C) which is an ester of a polyhydric alcohol and an aliphatic carboxylic acid and has a molecular weight of 500 to 2,000 g/mol, as well as molded articles thereof.The polycarbonate resin composition provides molded articles having excellent transparency, color and resistance to ultraviolet radiation, is excellent in heat stability at the time of molding and releasability and fully suppresses the production of a deposit on a metal mold.
摘要翻译： 一种聚碳酸酯树脂组合物，其包含100重量份的聚碳酸酯树脂（组分A），0.01至10重量份的选自特定的环亚氨基酯的至少一种紫外线吸收剂（组分B）和0.01至1 重量份分子量为500〜2000g / mol的作为多元醇和脂肪族羧酸的酯的脂肪酸酯化合物（C成分）及其成型品。 聚碳酸酯树脂组合物提供具有优异的透明性，耐紫外线性，耐紫外线性的成型体，成型时的热稳定性和脱模性优异，完全抑制金属模具上的沉积物的制造。
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