公开(公告)号：US3318874A

公开(公告)日：1967-05-09

申请号：US3318874D

CPC分类号： C07D251/68

公开(公告)号：US3045013A

公开(公告)日：1962-07-17

申请号：US3045013D

CPC分类号： C07D251/68

公开(公告)号：US2813864A

公开(公告)日：1957-11-19

申请号：US2813864D

CPC分类号： C07D251/68

公开(公告)号：US2762802A

公开(公告)日：1956-09-11

申请号：US2762802D

CPC分类号： C07D251/68

公开(公告)号：US2745830A

公开(公告)日：1956-05-15

申请号：US2745830D

CPC分类号： C07D251/68

公开(公告)号：US2703801A

公开(公告)日：1955-03-08

申请号：US2703801D

CPC分类号： C07D251/68 ,  C07D413/14

公开(公告)号：US2700665A

公开(公告)日：1955-01-25

申请号：US2700665D

CPC分类号： C07D251/68 ,  C07D403/12

公开(公告)号：US2666052A

公开(公告)日：1954-01-12

申请号：US2666052D

CPC分类号： C07D251/68 ,  C07D403/12 ,  C07D413/14

公开(公告)号：US20180236111A1

公开(公告)日：2018-08-23

申请号：US15961554

申请日：2018-04-24

申请人： The United States of America, as represented by the Secretary, Dept. of Health and Human Services ,  The Research Foundation of the State University of New York

发明人： Peter R. Williamson ,  Dale O. Kiesewetter ,  John Panepinto ,  Jin Qiu

IPC分类号： A61K51/04 ,  C07D251/68 ,  C07B59/00 ,  A61K31/53

CPC分类号： A61K51/0461 ,  A61K31/53 ,  C07B59/002 ,  C07D251/68

摘要： Disclosed herein are isotopically labeled calcofluor derivatives and uses of such to detect fungi, such as filamentous fungi, including Aspergillus species, such as by positron emission tomography (PET) scanning. In some examples, the disclosed compounds have a formula of wherein R1 is an amine, a hydroxyl group, a sulfide, a carboxylic acid, an amide, an alkyl, or aryl; R2 is —NHC(O)—R3-L or —C(O)NH—R3-L, wherein R3 is an aryl or an aliphatic group (such as alkyl); each R4 independently may be selected from halogen, aliphatic (such as alkyl), aryl, amine, hydroxyl, haloalkyl, carboxylic acid, amide, aralkyl, cyano, ester, thiol, thioether, or alkoxy; each R5 independently may be selected from hydrogen, aralkyl, alkyl, or aryl, with any one of the aralkyl, alkyl, or aryl groups optionally being substituted with any one of the substituents provided for R4; each n independently is 1, 2, 3, 4, or 5; and L is 18F or a chelator capable of chelating a radiolabel (such as chelators for [18F]AlF, 64Cu, 68Ga), 1,4,7,10-tetraazacyclododecane-tetraacetic acid (DOTA) or 1,4,7-triazacyclononane-triacetic acid (NOTA).

公开(公告)号：US09868858B2

公开(公告)日：2018-01-16

申请号：US14778101

申请日：2014-03-21

申请人： ARCHROMA IP GMBH

发明人： David Atkinson ,  Cristina Dominguez ,  Andrew Jackson

IPC分类号： D21H21/30 ,  C09B23/14 ,  C07D251/68 ,  D06P5/30 ,  C09K11/06 ,  D21H17/09 ,  D06L4/65

CPC分类号： C09B23/148 ,  C07D251/68 ,  C09K11/06 ,  C09K2211/1059 ,  D06L4/65 ,  D06P5/30 ,  D21H17/09 ,  D21H21/30

摘要： The instant invention relates to mixtures of stilbene compounds which provide superior fluorescent whitening effects when applied to the surface of ink-jet papers.