Improved Peptide Composition
    1.
    发明申请
    Improved Peptide Composition 有权
    改进的肽组成

    公开(公告)号:US20100173850A1

    公开(公告)日:2010-07-08

    申请号:US12514738

    申请日:2007-11-15

    IPC分类号: C07K7/06 A61K38/08 A61P25/28

    摘要: A peptide sequence of the form: X(Lys,Arg)XXXXX(Arg,Lys)X, wherein Lys and Arg arc replaceable and X is preferably one or more of the following amino acids: hydrophobic amino acid residues (eg Pro, Leu. Met, Ile), basic amino acid residues or threonine; and wherein the sequence is capable of engaging Λβ and ameliorating its SOD activity and/or metal ion binding.

    摘要翻译: 具有以下形式的肽序列:X(Lys,Arg)XXXXX(Arg,Lys)X,其中Lys和Arg可替代,X优选为以下氨基酸中的一个或多个:疏水性氨基酸残基(例如Pro,Leu。 Met,Ile),碱性氨基酸残基或苏氨酸; 并且其中所述序列能够接合Λ和bgr; 并改善其SOD活性和/或金属离子结合。