公开(公告)号：US07231249B2

公开(公告)日：2007-06-12

申请号：US10625526

申请日：2003-07-24

申请人： Morton M. Mower

发明人： Morton M. Mower

IPC分类号： A61N1/00

CPC分类号： A61N1/368 ,  A61N1/3627 ,  A61N1/3684

摘要： Methods, apparatus, and systems are provided to stimulate multiple sites in a heart. A controller senses electrical activity associated with sinus rhythm of the heart. A signal generator is configured to generate an electrical signal for stimulating the heart. Based on the electrical signal, a distributor circuit then distributes the stimulating signals, such as pacing pulses, to a heart. The distributor circuit may vary the delay time between stimulating signals, inhibit a stimulating signal, trigger application of a stimulating signal, or vary the characteristics, such as the pulse width and amplitude, of a stimulating signal.

摘要翻译： 提供方法，装置和系统以刺激心脏中的多个部位。 控制器感测与心脏窦性心律相关的电活动。 信号发生器被配置为产生用于刺激心脏的电信号。 基于电信号，分配器电路然后将刺激信号（例如起搏脉冲）分配到心脏。 分配器电路可以改变刺激信号之间的延迟时间，抑制刺激信号，触发施加刺激信号，或改变刺激信号的特性，例如脉冲宽度和幅度。

公开(公告)号：US08744558B2

公开(公告)日：2014-06-03

申请号：US11692114

申请日：2007-03-27

申请人： Morton M. Mower

发明人： Morton M. Mower

IPC分类号： A61N1/362

CPC分类号： A61N1/368 ,  A61N1/3627

摘要： Methods, apparatus, and systems are provided to control contraction of the heart. At least one sensing element receives signals indicating electrical activity of sinus rhythm of the heart. The electrical activity is monitored and analyzed to detect an event. In addition, the electrical activity is monitored to detect, for example, premature stimulation and contraction of a portion of the heart, such as the left ventricle. Contraction in the pre-excited portion of the heart is then suppressed using electrical pulses. The heart may then be allowed to contract naturally, or a stimulating pulse may be applied to assist the heart in contracting.

摘要翻译： 提供了方法，装置和系统来控制心脏收缩。 至少一个感测元件接收指示心脏的窦性心律的电活动的信号。 监测和分析电活动以检测事件。 此外，监测电活动以检测例如心脏的一部分例如左心室的过早刺激和收缩。 然后使用电脉冲抑制心脏的预激动部分的收缩。 然后可以让心脏自然收缩，或者可以施加刺激性脉搏来帮助心脏收缩。

公开(公告)号：US20120253418A1

公开(公告)日：2012-10-04

申请号：US13487891

申请日：2012-06-04

申请人： Morton M. MOWER

发明人： Morton M. MOWER

IPC分类号： A61N1/365

CPC分类号： A61N1/368 ,  A61N1/3627 ,  A61N1/3684

摘要： Methods, apparatus, and systems are provided to stimulate multiple sites in a heart. A controller senses electrical activity associated with sinus rhythm of the heart. A signal generator is configured to generate an electrical signal for stimulating the heart. Based on the electrical signal, a distributor circuit then distributes the stimulating signals, such as pacing pulses, to a heart. The distributor circuit may vary the delay time between stimulating signals, inhibit a stimulating signal, trigger application of a stimulating signal, or vary the characteristics, such as the pulse width and amplitude, of a stimulating signal.

摘要翻译： 提供方法，装置和系统以刺激心脏中的多个部位。 控制器感测与心脏窦性心律相关的电活动。 信号发生器被配置为产生用于刺激心脏的电信号。 基于电信号，分配器电路然后将刺激信号（例如起搏脉冲）分配到心脏。 分配器电路可以改变刺激信号之间的延迟时间，抑制刺激信号，触发施加刺激信号，或改变刺激信号的特性，例如脉冲宽度和幅度。

公开(公告)号：US20070191893A1

公开(公告)日：2007-08-16

申请号：US11692114

申请日：2007-03-27

申请人： Morton MOWER

发明人： Morton MOWER

IPC分类号： A61N1/362

CPC分类号： A61N1/368 ,  A61N1/3627

摘要： Methods, apparatus, and systems are provided to control contraction of the heart. At least one sensing element receives signals indicating electrical activity of sinus rhythm of the heart. The electrical activity is monitored and analyzed to detect an event. In addition, the electrical activity is monitored to detect, for example, premature stimulation and contraction of a portion of the heart, such as the left ventricle. Contraction in the pre-excited portion of the heart is then suppressed using electrical pulses. The heart may then be allowed to contract naturally, or a stimulating pulse may be applied to assist the heart in contracting.

摘要翻译： 提供了方法，装置和系统来控制心脏收缩。 至少一个感测元件接收指示心脏的窦性心律的电活动的信号。 监测和分析电活动以检测事件。 此外，监测电活动以检测例如心脏的一部分例如左心室的过早刺激和收缩。 然后使用电脉冲抑制心脏的预激动部分的收缩。 然后可以让心脏自然收缩，或者可以施加刺激性脉搏来帮助心脏收缩。

公开(公告)号：US09566444B2

公开(公告)日：2017-02-14

申请号：US14272730

申请日：2014-05-08

申请人： Morton M. Mower

发明人： Morton M. Mower

IPC分类号： A61N1/36 ,  A61N1/368 ,  A61N1/362

CPC分类号： A61N1/368 ,  A61N1/3627 ,  A61N1/3684

摘要： Methods, apparatus, and systems are provided to stimulate multiple sites in a heart. A controller senses electrical activity associated with sinus rhythm of the heart. A signal generator is configured to generate an electrical signal for stimulating the heart. Based on the electrical signal, a distributor circuit then distributes the stimulating signals, such as pacing pulses, to a heart. The distributor circuit may vary the delay time between stimulating signals, inhibit a stimulating signal, trigger application of a stimulating signal, or vary the characteristics, such as the pulse width and amplitude, of a stimulating signal.

摘要翻译： 提供方法，装置和系统以刺激心脏中的多个部位。 控制器感测与心脏窦性心律相关的电活动。 信号发生器被配置为产生用于刺激心脏的电信号。 基于电信号，分配器电路然后将刺激信号（例如起搏脉冲）分配到心脏。 分配器电路可以改变刺激信号之间的延迟时间，抑制刺激信号，触发施加刺激信号，或改变刺激信号的特性，例如脉冲宽度和幅度。

公开(公告)号：US08249725B2

公开(公告)日：2012-08-21

申请号：US11745593

申请日：2007-05-08

申请人： Morton M Mower

发明人： Morton M Mower

IPC分类号： A61N1/08

CPC分类号： A61N1/368 ,  A61N1/3627 ,  A61N1/3684

摘要： Methods, apparatus, and systems are provided to stimulate multiple sites in a heart. A controller senses electrical activity associated with sinus rhythm of the heart. A signal generator is configured to generate an electrical signal for stimulating the heart. Based on the electrical signal, a distributor circuit then distributes the stimulating signals, such as pacing pulses, to a heart. The distributor circuit may vary the delay time between stimulating signals, inhibit a stimulating signal, trigger application of a stimulating signal, or vary the characteristics, such as the pulse width and amplitude, of a stimulating signal.

摘要翻译： 提供方法，装置和系统以刺激心脏中的多个部位。 控制器感测与心脏窦性心律相关的电活动。 信号发生器被配置为产生用于刺激心脏的电信号。 基于电信号，分配器电路然后将刺激信号（例如起搏脉冲）分配到心脏。 分配器电路可以改变刺激信号之间的延迟时间，抑制刺激信号，触发施加刺激信号，或改变刺激信号的特性，例如脉冲宽度和幅度。

公开(公告)号：USRE39897E1

公开(公告)日：2007-10-23

申请号：US10214474

申请日：2002-08-08

申请人： Morton M. Mower

发明人： Morton M. Mower

IPC分类号： A61N1/362

CPC分类号： A61N1/3627 ,  A61N1/368 ,  A61N1/3684

摘要： A method of treating hemodynamic disfunction by simultaneously pacing both ventricles of a heart. At least one ECG amplifier is arranged to separately detect contraction of each ventricle and a stimulator is then activated for issuing stimulating pulses to both ventricles in a manner to assure simultaneous contraction of both ventricles, thereby to assure hemodynamic efficiency. A first ventricle is stimulated simultaneously with contraction of a second ventricle when the first fails to properly contract. Further, both ventricles are stimulated after lapse of a predetermined A-V escape interval. One of a pair of electrodes, connected in series, in placed through the superior vena cava into the right ventricle and a second is placed in the coronary sinus about the left ventricle. Each electrode performs both pacing and sensing functions. The pacer is particularly suitable for treating bundle branch blocks or slow conduction in a portion of the ventricles.

摘要翻译： 通过同时起搏心脏的两个心室来治疗血液动力学障碍的方法。 至少一个ECG放大器被设置为分别检测每个心室的收缩，然后激活刺激器以便以两种心室的刺激脉冲发出刺激脉冲，以确保两个脑室同时收缩，从而确保血液动力学效率。 当第一个心室不能正常收缩时，第一个心室与第二个心室的收缩同时受到刺激。 此外，在经过预定的A-V逃逸间隔之后刺激两个心室。 串联连接的一对电极之一，通过上腔静脉置入右心室，另一个电极放置在围绕左心室的冠状窦中。 每个电极执行起搏和感应功能。 该起搏器特别适用于治疗束支传导阻滞或在一部分心室中缓慢传导。

公开(公告)号：US20050021096A1

公开(公告)日：2005-01-27

申请号：US10625526

申请日：2003-07-24

申请人： Morton Mower

发明人： Morton Mower

IPC分类号： A61N1/362 ,  A61N1/368

CPC分类号： A61N1/368 ,  A61N1/3627 ,  A61N1/3684

摘要： Methods, apparatus, and systems are provided to stimulate multiple sites in a heart. A controller senses electrical activity associated with sinus rhythm of the heart. A signal generator is configured to generate an electrical signal for stimulating the heart. Based on the electrical signal, a distributor circuit then distributes the stimulating signals, such as pacing pulses, to a heart. The distributor circuit may vary the delay time between stimulating signals, inhibit a stimulating signal, trigger application of a stimulating signal, or vary the characteristics, such as the pulse width and amplitude, of a stimulating signal.

摘要翻译： 提供方法，装置和系统以刺激心脏中的多个部位。 控制器感测与心脏窦性心律相关的电活动。 信号发生器被配置为产生用于刺激心脏的电信号。 基于电信号，分配器电路然后将刺激信号（例如起搏脉冲）分配到心脏。 分配器电路可以改变刺激信号之间的延迟时间，抑制刺激信号，触发施加刺激信号，或改变刺激信号的特性，例如脉冲宽度和幅度。

公开(公告)号：US08761905B2

公开(公告)日：2014-06-24

申请号：US13487891

申请日：2012-06-04

申请人： Morton M. Mower

发明人： Morton M. Mower

IPC分类号： A61N1/362

CPC分类号： A61N1/368 ,  A61N1/3627 ,  A61N1/3684

摘要： Methods, apparatus, and systems are provided to stimulate multiple sites in a heart. A controller senses electrical activity associated with sinus rhythm of the heart. A signal generator is configured to generate an electrical signal for stimulating the heart. Based on the electrical signal, a distributor circuit then distributes the stimulating signals, such as pacing pulses, to a heart. The distributor circuit may vary the delay time between stimulating signals, inhibit a stimulating signal, trigger application of a stimulating signal, or vary the characteristics, such as the pulse width and amplitude, of a stimulating signal.

摘要翻译： 提供方法，装置和系统以刺激心脏中的多个部位。 控制器感测与心脏窦性心律相关的电活动。 信号发生器被配置为产生用于刺激心脏的电信号。 基于电信号，分配器电路然后将刺激信号（例如起搏脉冲）分配到心脏。 分配器电路可以改变刺激信号之间的延迟时间，抑制刺激信号，触发施加刺激信号，或改变刺激信号的特性，例如脉冲宽度和幅度。

公开(公告)号：US20070208387A1

公开(公告)日：2007-09-06

申请号：US11745593

申请日：2007-05-08

申请人： Morton MOWER

发明人： Morton MOWER

IPC分类号： A61N1/36

CPC分类号： A61N1/368 ,  A61N1/3627 ,  A61N1/3684

摘要： Methods, apparatus, and systems are provided to stimulate multiple sites in a heart. A controller senses electrical activity associated with sinus rhythm of the heart. A signal generator is configured to generate an electrical signal for stimulating the heart. Based on the electrical signal, a distributor circuit then distributes the stimulating signals, such as pacing pulses, to a heart. The distributor circuit may vary the delay time between stimulating signals, inhibit a stimulating signal, trigger application of a stimulating signal, or vary the characteristics, such as the pulse width and amplitude, of a stimulating signal.

摘要翻译： 提供方法，装置和系统以刺激心脏中的多个部位。 控制器感测与心脏窦性心律相关的电活动。 信号发生器被配置为产生用于刺激心脏的电信号。 基于电信号，分配器电路然后将刺激信号（例如起搏脉冲）分配到心脏。 分配器电路可以改变刺激信号之间的延迟时间，抑制刺激信号，触发施加刺激信号，或改变刺激信号的特性，例如脉冲宽度和幅度。