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    Acid tolerant Lactobacillus sakei probio-65 with the ability of growth suppression of pathogenic microorganisms and the anti-allergic effect
    1.
    发明授权
    Acid tolerant Lactobacillus sakei probio-65 with the ability of growth suppression of pathogenic microorganisms and the anti-allergic effect 有权
    耐酸性乳酸杆菌probi-65具有生长抑制病原微生物的能力和抗过敏作用

    公开(公告)号：US08034606B2

    公开(公告)日：2011-10-11

    申请号：US11883398

    申请日：2006-01-27

    申请人： Yong Ha Park ,  In-seon Lee ,  Hong-ik Kim ,  Kook-hee Kang

    发明人： Yong Ha Park ,  In-seon Lee ,  Hong-ik Kim ,  Kook-hee Kang

    IPC分类号： C12N1/20

    CPC分类号： C12R1/225 ,  A23K10/18 ,  A23L33/135 ,  A61K8/99 ,  A61K35/747 ,  A61Q17/005 ,  A61Q19/00

    摘要： Disclosed are a novel tactic acid bacterium, Lactobacillus sakei Probio-65, and the use thereof. The L. sakei Probio-65 strain has acid tolerance, bile acid tolerance and antibiotic resistance, inhibits the growth of harmful pathogenic microorganisms in the body and the intestine of animals, and has immunuenhancing activity. In particular, the novel strain inhibits the growth of Staphylocccus aureus, which is known to be a factor aggravating atopic dermatitis. Thus, the novel strain is useful for preventing or treating atopic dermatitis and allergy-related disorders. Also, the novel strain stabilizes intestinal microflors by inhibiting the abnormal proliferation of harmful microorganisms in the intestine. The L. sakei Probio-65 strain or a culture thereof is useful in pharmaceutical, feed, food, and cosmetic compositions.

    摘要翻译： 公开了一种新型的乳酸菌，益气乳杆菌Probio-65及其用途。 李氏酵母Probio-65菌株具有耐酸性，胆汁酸耐受性和抗生素抗性，抑制动物身体和肠道中有害致病微生物的生长，并具有免疫增强活性。 特别地，新菌株抑制金黄色葡萄球菌的生长，其已知是加重特应性皮炎的因素。 因此，新型菌株可用于预防或治疗特应性皮炎和过敏相关疾病。 此外，新菌株通过抑制肠中有害微生物的异常增殖来稳定肠道微生物群落。 莱氏酵母Probio-65菌株或其培养物可用于药物，饲料，食品和化妆品组合物中。