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    Portable vehicle battery jump start apparatus with safety protection and jumper cable device thereof
    2.
    发明授权
    Portable vehicle battery jump start apparatus with safety protection and jumper cable device thereof 有权

    公开(公告)号：US11447023B2

    公开(公告)日：2022-09-20

    申请号：US16450422

    申请日：2019-06-24

    申请人： THE NOCO COMPANY

    发明人： Jonathan Lewis Nook ,  William Knight Nook ,  James Richard Stanfield ,  Derek Michael Underhill

    IPC分类号： B60L53/14 ,  H02J7/00 ,  H02J7/34 ,  H02J1/10

    摘要： A handheld device for jump starting a vehicle engine includes a rechargeable lithium ion battery pack and a microcontroller. The lithium ion battery is coupled to a power output port of the device through a FET smart switch actuated by the microcontroller. A vehicle battery isolation sensor connected in circuit with positive and negative polarity outputs detects the presence of a vehicle battery connected between the positive and negative polarity outputs. A reverse polarity sensor connected in circuit with the positive and negative polarity outputs detects the polarity of a vehicle battery connected between the positive and negative polarity outputs, such that the microcontroller will enable power to be delivered from the lithium ion power pack to the output port only when a good battery is connected to the output port and only when the battery is connected with proper polarity of positive and negative terminals.

    Mopping unit
    7.
    发明授权
    Mopping unit 有权

    公开(公告)号：US11337577B2

    公开(公告)日：2022-05-24

    申请号：US16584255

    申请日：2019-09-26

    申请人： Tyroler Ltd.

    发明人： Dan Tyroler

    IPC分类号： A47L13/256 ,  A47L13/258

    摘要： Provided is a mopping unit including: a mop base, a head unit and a coupling element; wherein the coupling element having two parallel elongated reinforcing end segments integral with and flanking a central, coupling segment; the base, being a single-piece molded article having a bottom face and a top face; two elongated bores are formed in elongated abutments on the top face, each accommodating one of the two reinforcing end segments; the base being configured for attaching a mopping substrate on the bottom face; and wherein the head unit being pivotally coupled to said central segment to permit it to pivot about a first axis essentially parallel to said central segment and including a receptacle for an end of a mopping handle.

    Pharmaceutical composition for treatment of lung cancer comprising glucocorticoid-based compound
    10.
    发明授权
    Pharmaceutical composition for treatment of lung cancer comprising glucocorticoid-based compound 有权

    公开(公告)号：US11260062B2

    公开(公告)日：2022-03-01

    申请号：US15772714

    申请日：2016-11-02

    申请人： AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

    发明人： Sang-Min Jeon

    IPC分类号： A61K31/573 ,  A61P35/00 ,  A61K31/404 ,  A61K31/436

    摘要： Provided is a composition for treating or ameliorating lung cancer including a glucocorticoid-based compound, a glucocorticoid-based compound and an mTOR inhibitor, or a glucocorticoid-based compound and an AMPK inhibitor as an active ingredient. The glucocorticoid-based compounds inhibit the growth of cancer cells by suppressing NRF2 in KEAP1 mutant lung cancer or KEAP1 and LKB1 mutant lung cancer, and exhibit a more potent anticancer effect when used in combination with the mTOR inhibitor, and thus the compounds can be effectively used as anticancer agents for mutant lung cancer. Further, the glucocorticoid-based compounds exhibit a strong anticancer synergistic effect in a low nutritional state when treated in combination with an AMPK inhibitor in KEAP1 and LKB1 normal lung cancer, and thus the compounds can also be used as an anticancer agent for KEAP1 normal lung cancer.