BIOLUMINESCENCE RESONANCE ENERGY TRANSFER (BRET) SYSTEMS AND METHODS OF USE THEREOF
    1.
    发明申请
    BIOLUMINESCENCE RESONANCE ENERGY TRANSFER (BRET) SYSTEMS AND METHODS OF USE THEREOF 有权
    生物共振能量转移(BRET)系统及其使用方法

    公开(公告)号:US20100047813A1

    公开(公告)日:2010-02-25

    申请号:US12365984

    申请日:2009-02-05

    IPC分类号: G01N33/53

    CPC分类号: G01N33/542 C12Q1/66

    摘要: Briefly described, embodiments of this disclosure include bioluminescence resonance energy transfer (BRET) systems, methods of detecting a protein-protein interaction, noninvasive methods for detecting the interaction of a first protein with a second protein within a living animal, methods to determine the efficacy of a test compound administered to modulate the interaction of a first protein with a second protein in a living animal, BRET vectors, kits relating to each of the above, transgenic cell or progeny thereof and/or animals relating to each of the above, and the like.

    摘要翻译: 简要描述,本公开的实施方案包括生物发光共振能量转移(BRET)系统,检测蛋白质 - 蛋白质相互作用的方法,用于检测活体动物中第一种蛋白质与第二种蛋白质的相互作用的非侵入性方法,确定功效的方法 施用以调节活体动物中第一蛋白质与第二蛋白质的相互作用的测试化合物,BRET载体,与上述每种相关的试剂盒,转基因细胞或其后代和/或与上述每种相关的动物,和/或 类似。

    Bioluminescence resonance energy transfer (BRET) systems and methods of use thereof
    2.
    发明申请
    Bioluminescence resonance energy transfer (BRET) systems and methods of use thereof 有权
    生物发光共振能量转移(BRET)系统及其使用方法

    公开(公告)号:US20070077609A1

    公开(公告)日:2007-04-05

    申请号:US11373679

    申请日:2006-03-10

    IPC分类号: C12Q1/66 G06K9/00

    CPC分类号: G01N33/542 C12Q1/66

    摘要: Briefly described, embodiments of this disclosure include bioluminescence resonance energy transfer (BRET) systems, methods of detecting a protein-protein interaction, noninvasive methods for detecting the interaction of a first protein with a second protein within a living animal, methods to determine the efficacy of a test compound administered to modulate the interaction of a first protein with a second protein in a living animal, BRET vectors, kits relating to each of the above, transgenic cell or progeny thereof and/or animals relating to each of the above, and the like.

    摘要翻译: 简要描述,本公开的实施方案包括生物发光共振能量转移(BRET)系统,检测蛋白质 - 蛋白质相互作用的方法,用于检测活体动物中第一种蛋白质与第二种蛋白质的相互作用的非侵入性方法,确定功效的方法 施用以调节活体动物中第一蛋白质与第二蛋白质的相互作用的测试化合物,BRET载体,与上述每种相关的试剂盒,转基因细胞或其后代和/或与上述每种相关的动物,和/或 类似。

    Bioluminescence resonance energy transfer (BRET) systems and methods of use thereof
    3.
    发明授权
    Bioluminescence resonance energy transfer (BRET) systems and methods of use thereof 有权
    生物发光共振能量转移(BRET)系统及其使用方法

    公开(公告)号:US07842469B2

    公开(公告)日:2010-11-30

    申请号:US12365984

    申请日:2009-02-05

    IPC分类号: G01N33/53

    CPC分类号: G01N33/542 C12Q1/66

    摘要: Briefly described, embodiments of this disclosure include bioluminescence resonance energy transfer (BRET) systems, methods of detecting a protein-protein interaction, noninvasive methods for detecting the interaction of a first protein with a second protein within a living animal, methods to determine the efficacy of a test compound administered to modulate the interaction of a first protein with a second protein in a living animal, BRET vectors, kits relating to each of the above, transgenic cell or progeny thereof and/or animals relating to each of the above, and the like.

    摘要翻译: 简要描述,本公开的实施方案包括生物发光共振能量转移(BRET)系统,检测蛋白质 - 蛋白质相互作用的方法,用于检测活体动物中第一种蛋白质与第二种蛋白质的相互作用的非侵入性方法,确定功效的方法 施用以调节活体动物中第一蛋白质与第二蛋白质的相互作用的测试化合物,BRET载体,与上述每种相关的试剂盒,转基因细胞或其后代和/或与上述每种相关的动物,和/或 类似。

    Bioluminescence resonance energy transfer (BRET) systems and methods of use thereof
    4.
    发明授权
    Bioluminescence resonance energy transfer (BRET) systems and methods of use thereof 有权
    生物发光共振能量转移(BRET)系统及其使用方法

    公开(公告)号:US07507565B2

    公开(公告)日:2009-03-24

    申请号:US11373679

    申请日:2006-03-10

    IPC分类号: C12N9/02 G01N33/00 C07H21/04

    CPC分类号: G01N33/542 C12Q1/66

    摘要: Briefly described, embodiments of this disclosure include bioluminescence resonance energy transfer (BRET) systems, methods of detecting a protein-protein interaction, noninvasive methods for detecting the interaction of a first protein with a second protein within a living animal, methods to determine the efficacy of a test compound administered to modulate the interaction of a first protein with a second protein in a living animal, BRET vectors, kits relating to each of the above, transgenic cell or progeny thereof and/or animals relating to each of the above, and the like.

    摘要翻译: 简要描述,本公开的实施方案包括生物发光共振能量转移(BRET)系统,检测蛋白质 - 蛋白质相互作用的方法,用于检测活体动物中第一种蛋白质与第二种蛋白质的相互作用的非侵入性方法,确定功效的方法 施用以调节活体动物中第一蛋白质与第二蛋白质的相互作用的测试化合物,BRET载体,与上述每种相关的试剂盒,转基因细胞或其后代和/或与上述每种相关的动物,和/或 类似。