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公开(公告)号:US20080108551A1
公开(公告)日:2008-05-08
申请号:US11823209
申请日:2007-06-27
申请人: Adele Horobin , Kevin Shakesheff , David Pritchard
发明人: Adele Horobin , Kevin Shakesheff , David Pritchard
CPC分类号: C12N9/6408 , A61K38/00
摘要: The invention generally provides compositions and methods that promote wound healing. Such compositions comprise isolated L. sericata polypeptides having serine protease activity. Desirably, the serine protease degrades fibronectin. The invention further provides biologically active fragments of fibronectin that promote wound healing that are the degradation products of incubation with ES.
摘要翻译: 本发明通常提供促进伤口愈合的组合物和方法。 这种组合物包含具有丝氨酸蛋白酶活性的分离的丝胶多糖。 希望丝氨酸蛋白酶降解纤连蛋白。 本发明还提供促进伤口愈合的纤连蛋白的生物活性片段,其是与ES孵育的降解产物。