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公开(公告)号:US10888380B2
公开(公告)日:2021-01-12
申请号:US16171515
申请日:2018-10-26
Applicant: Alcon Research, Ltd.
Inventor: Zsolt Bor , Imre Hegedus
Abstract: Systems and methods for intraocular lens selection include receiving, by one or more computing devices implementing a prediction engine, pre-operative multi-dimensional images of an eye; extracting, by the prediction engine, pre-operative measurements of the eye based on the pre-operative images; estimating, by the prediction engine using a prediction model based on a machine learning strategy, a post-operative position of an intraocular lens based on the extracted pre-operative measurements; selecting a power of the intraocular lens based on the estimated post-operative position of the intraocular lens; and selecting the intraocular lens based on the selected power. In some embodiments, the systems and methods further include receiving post-operative multi-dimensional images of the eye after implantation of the selected intraocular lens, extracting post-operative measurements of the eye, and updating the prediction model based on the pre-operative measurements and the post-operative measurements.
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公开(公告)号:US10828320B2
公开(公告)日:2020-11-10
申请号:US16721443
申请日:2019-12-19
Applicant: Alcon Research, Ltd.
Inventor: James W. Davis , Howard Allen Ketelson , Elaine E. Campbell , David L. Meadows , Rekha Rangarajan
IPC: A61K31/736 , A61K9/00 , A61K47/02 , A61K47/10 , A61K47/26 , A61K47/36 , A61K47/32 , A61K31/728
Abstract: The present invention relates to artificial tear compositions and ophthalmic compositions suitable for drug delivery. In one embodiment of the present invention, the compositions comprise a galactomannan polymer such as guar or hydroxypropyl guar, hyaluronic acid, and a cis-diol such as sorbitol. In a preferred embodiment, the compositions also comprise a borate compound.
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公开(公告)号:US10660704B2
公开(公告)日:2020-05-26
申请号:US15397283
申请日:2017-01-03
Applicant: Alcon Research, Ltd.
Inventor: Ronald T. Smith
Abstract: An optical surgical probe includes a handpiece, a light guide within the handpiece, and a multi-spot generator at a distal end of the handpiece. The handpiece is configured to optically couple to a light source. The light guide is configured to carry a light beam from the light source to a distal end of the handpiece. The multi-spot generator includes a faceted optical element with a faceted end surface spaced from a distal end of the light guide. The faceted end surface includes at least one facet oblique to a path of the light beam.
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公开(公告)号:US20200138853A1
公开(公告)日:2020-05-07
申请号:US16721443
申请日:2019-12-19
Applicant: Alcon Research, Ltd.
Inventor: James W. Davis , Howard Allen Ketelson , Elaine E. Campbell , David L. Meadows , Rekha Rangarajan
IPC: A61K31/736 , A61K9/00 , A61K47/02 , A61K47/10 , A61K47/26 , A61K31/728 , A61K47/36 , A61K47/32
Abstract: The present invention relates to artificial tear compositions and ophthalmic compositions suitable for drug delivery. In one embodiment of the present invention, the compositions comprise a galactomannan polymer such as guar or hydroxypropyl guar, hyaluronic acid, and a cis-diol such as sorbitol. In a preferred embodiment, the compositions also comprise a borate compound.
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公开(公告)号:US10478532B2
公开(公告)日:2019-11-19
申请号:US15842991
申请日:2017-12-15
Applicant: Alcon Research, Ltd.
Inventor: Glenn Robert Sussman , Mikhail Boukhny , John Morgan Bourne
Abstract: A surgical hand piece is described that maintains a vacuum pressure within the hand piece at a selected level. A check valve is provided substantially near an inlet of an integrated aspirating pump. The check valve opens to introduce fluid into the hand piece to maintain the vacuum pressure within the hand piece at or above the selected level so as to prevent or substantially reduce post-occlusion flow.
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公开(公告)号:US20190290380A1
公开(公告)日:2019-09-26
申请号:US16282403
申请日:2019-02-22
Applicant: Alcon Research, Ltd.
Inventor: Geoffrey C. Jawidzik
Abstract: The present disclosure describes composite frame systems. The internal composite frame system may include at least one composite frame component including an intermediate frame element having a first side and a second side. A first plate may be positioned on the first side, and a second plate may be positioned on the second side. One or more fastener assemblies are operable to couple the first and second plates to the intermediate frame element.
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公开(公告)号:US10328025B2
公开(公告)日:2019-06-25
申请号:US15989383
申请日:2018-05-25
Applicant: ALCON RESEARCH, LTD.
Inventor: Howard Allen Ketelson , David L. Meadows
Abstract: The present invention is directed to an ophthalmic emulsion. The emulsion has a unique combination of ingredients that promotes the stability of small oil droplets within the emulsion. The emulsion also includes a mucoadhesive polymer that aid in delivering a lipid to the ocular surface.
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公开(公告)号:US10039565B2
公开(公告)日:2018-08-07
申请号:US15075861
申请日:2016-03-21
Applicant: Alcon Research, Ltd.
Inventor: Guido Vezzu
Abstract: Membrane forceps for performing an ILM or ERM peel procedure include a handle, a tube extending from the handle, and forceps jaws extending from the tube. The forceps jaws may be configured to grasp an ILM or ERM, and may include an outer surface having a roughened surface. The roughened surface may be structurally configured to aid in gaining an edge of the ILM or ERM.
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公开(公告)号:US20180126050A1
公开(公告)日:2018-05-10
申请号:US15842991
申请日:2017-12-15
Applicant: Alcon Research, Ltd.
Inventor: Glenn Robert Sussman , Mikhail Boukhny , John Morgan Bourne
CPC classification number: A61M1/0031 , A61F9/00745 , A61M1/0039 , A61M1/0058 , A61M2210/0612
Abstract: A surgical hand piece is described that maintains a vacuum pressure within the hand piece at a selected level. A check valve is provided substantially near an inlet of an integrated aspirating pump. The check valve opens to introduce fluid into the hand piece to maintain the vacuum pressure within the hand piece at or above the selected level so as to prevent or substantially reduce post-occlusion flow.
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公开(公告)号:US09910338B2
公开(公告)日:2018-03-06
申请号:US14569798
申请日:2014-12-15
Applicant: Alcon Research, Ltd.
Inventor: Ronald T. Smith
IPC: A61B18/18 , G02F1/29 , G02F1/13 , A61F9/008 , G02F1/1334
CPC classification number: G02F1/29 , A61F9/00823 , A61F2009/00863 , A61F2009/00897 , G02F1/1326 , G02F1/1334 , G02F1/292
Abstract: In certain embodiments, a system may include a housing, one or more lenses, and a scanning system. The housing has an interior region. A lens is disposed within the interior region and transmits a light beam. The scanning system is disposed within the interior region and comprises a number of scanning cells, where each scanning cell comprises an electro-optical (EO) material. The scanning system performs the following for a number of iterations to yield a spot pattern: receive one or more voltages and electrically steer the light beam with the EO material from a current direction to a next direction in response to the voltages.
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