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公开(公告)号:US20060056580A1
公开(公告)日:2006-03-16
申请号:US11222949
申请日:2005-09-09
申请人: John Frangioni , Alec De Grand
发明人: John Frangioni , Alec De Grand
CPC分类号: G01N23/223 , G01N2223/076
摘要: The invention is based, in part, on the discovery that by combining certain components one can generate a tissue-like phantom that mimics any desired tissue, is simple and inexpensive to prepare, and is stable over many weeks or months. In addition, new multi-modal imaging objects (e.g., beads) can be inserted into the phantoms to mimic tissue pathologies, such as cancer, or merely to serve as calibration standards. These objects can be imaged using one, two, or more (e.g., four) different imaging modalities (e.g., x-ray computed tomography (CT), positron emission tomography (PET), single photon emission computed tomography (SPECT), and near-infrared (NIR) fluorescence) simultaneously.
摘要翻译: 本发明部分地基于通过组合某些组分的发现,可以产生模拟任何所需组织的组织样模型,其制备简单且便宜,并且在多个星期或数月内是稳定的。 此外,可以将新的多模态成像对象(例如珠)插入到模体中以模拟诸如癌症的组织病理学,或者仅用作校准标准。 这些物体可以使用一个,两个或更多(例如四个)不同的成像模式(例如,x射线计算机断层摄影(CT),正电子发射断层摄影(PET),单光子发射计算机断层摄影(SPECT)和近距离 - 红外(NIR)荧光)。