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公开(公告)号：US20100324874A9
公开(公告)日：2010-12-23
申请号：US10961523
申请日：2004-10-07
申请人： Alex Bangs , Kevin Bowling , Thomas Paterson
发明人： Alex Bangs , Kevin Bowling , Thomas Paterson
摘要： The invention encompasses systems, methods, and apparatus for predicting and monitoring an individual's response to a therapeutic regimen. The invention includes multiple virtual patients, an associating subsystem operable to associate the subject with one or more of the virtual patients, and a simulation engine operable to apply one or more experimental protocols to the one or more virtual patients identified with the subject to generate a set of outputs. The set of outputs can represent therapeutic efficacy, identify biomarkers for monitoring therapeutic efficacy, or merely report the status of the biological system as it represents a particular individual
摘要翻译： 本发明包括用于预测和监测个体对治疗方案的反应的系统，方法和装置。 本发明包括多个虚拟患者，可操作以将受试者与一个或多个虚拟患者相关联的关联子系统，以及可操作以将一个或多个实验协议应用于被识别为受试者的一个或多个虚拟患者以产生 一组输出 该组输出可以代表治疗功效，鉴定用于监测治疗功效的生物标志物，或仅仅报告生物系统的状态，因为它代表特定个体
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公开(公告)号：US20060031059A1
公开(公告)日：2006-02-09
申请号：US11248706
申请日：2005-10-11
申请人： Thomas Paterson , Alex Bangs
发明人： Thomas Paterson , Alex Bangs
IPC分类号： G06F9/45
CPC分类号： G16H50/50 , G06F19/00 , G06F19/324 , G06F19/325
摘要： A method of conducting a sequence of linked simulation operations, utilizing a computer-based simulation model, commences with the performance of a first simulation operation to generate an output condition. A further simulation operation, which is defined to sequentially follow the first simulation operation, is then formed utilizing the simulation model. The second simulation operation at least partially and automatically inherits the output condition generated by the first simulation operation as an input condition. In this way, the second simulation operation commences with a configuration captured from a preceding simulation operation as an input condition. Multiple simulation operations may at least partially inherit a configuration from the first simulation operation.
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公开(公告)号：US20050131663A1
公开(公告)日：2005-06-16
申请号：US10961523
申请日：2004-10-07
申请人： Alex Bangs , Kevin Bowling , Thomas Paterson
发明人： Alex Bangs , Kevin Bowling , Thomas Paterson
CPC分类号： G16H50/50
摘要： The invention encompasses systems, methods, and apparatus for predicting and monitoring an individual's response to a therapeutic regimen. The invention includes multiple virtual patients, an associating subsystem operable to associate the subject with one or more of the virtual patients, and a simulation engine operable to apply one or more experimental protocols to the one or more virtual patients identified with the subject to generate a set of outputs. The set of outputs can represent therapeutic efficacy, identify biomarkers for monitoring therapeutic efficacy, or merely report the status of the biological system as it represents a particular individual
摘要翻译： 本发明包括用于预测和监测个体对治疗方案的反应的系统，方法和装置。 本发明包括多个虚拟患者，可操作以将受试者与一个或多个虚拟患者相关联的关联子系统，以及可操作以将一个或多个实验协议应用于被识别为受试者的一个或多个虚拟患者以产生 一组输出 该组输出可以代表治疗功效，鉴定用于监测治疗功效的生物标志物，或仅仅报告生物系统的状态，因为它代表特定个体
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