公开(公告)号：US07524879B2

公开(公告)日：2009-04-28

申请号：US11757880

申请日：2007-06-04

申请人： Gregory N. Beatch ,  Bertrand M. C. Plouvier ,  Tao Sheng ,  Michael J. A. Walker ,  Richard A. Wall ,  Sandro L. Yong ,  Jeff Jiqun Zhu ,  Alexander R. Zolotoy

发明人： Gregory N. Beatch ,  Bertrand M. C. Plouvier ,  Tao Sheng ,  Michael J. A. Walker ,  Richard A. Wall ,  Sandro L. Yong ,  Jeff Jiqun Zhu ,  Alexander R. Zolotoy

IPC分类号： A61K31/40

CPC分类号： A61K31/40 ,  A61K9/0019 ,  A61K31/4015 ,  C07D209/36

摘要： Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.

公开(公告)号：US20100056603A1

公开(公告)日：2010-03-04

申请号：US12412010

申请日：2009-03-26

申请人： Gregory N. Beatch ,  Bertrand M.C. Plouvier ,  Tao Sheng ,  Michael J.A. Walker ,  Richard A. Wall ,  Sandro L. Yong ,  Jeff Jiqun Zhu ,  Alexander R. Zolotoy

发明人： Gregory N. Beatch ,  Bertrand M.C. Plouvier ,  Tao Sheng ,  Michael J.A. Walker ,  Richard A. Wall ,  Sandro L. Yong ,  Jeff Jiqun Zhu ,  Alexander R. Zolotoy

IPC分类号： A61K31/40 ,  A61P9/06

CPC分类号： A61K31/40 ,  A61K9/0019 ,  A61K31/4015 ,  C07D209/36

摘要： Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.

公开(公告)号：US08008342B2

公开(公告)日：2011-08-30

申请号：US12412010

申请日：2009-03-26

申请人： Gregory N. Beatch ,  Bertrand M. C. Plouvier ,  Tao Sheng ,  Michael J. A. Walker ,  Richard A. Wall ,  Sandro L. Yong ,  Jeff Jiqun Zhu ,  Alexander R. Zolotoy

发明人： Gregory N. Beatch ,  Bertrand M. C. Plouvier ,  Tao Sheng ,  Michael J. A. Walker ,  Richard A. Wall ,  Sandro L. Yong ,  Jeff Jiqun Zhu ,  Alexander R. Zolotoy

IPC分类号： A61K31/40

CPC分类号： A61K31/40 ,  A61K9/0019 ,  A61K31/4015 ,  C07D209/36

摘要： Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.