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公开(公告)号:US20230256017A1
公开(公告)日:2023-08-17
申请号:US17801669
申请日:2021-02-26
申请人: Jennifer BROGDON , Glenn DRANOFF , Michael R. GREENE , Anniesha HACK , Olja KODRASI , Elizabeth Dorothy PRATICO , Andrew PRICE , Andrew Marc STEIN , Amy RAYO , Jennifer YANG , Brian Walter GRANDA , Novartis AG
发明人: Jennifer BROGDON , Glenn DRANOFF , Michael R. GREENE , Anniesha HACK , Olja KODRASI , Elizabeth Dorothy PRATICO , Andrew PRICE , Andrew Marc STEIN , Amy RAYO , Jennifer YANG , Brian Walter GRANDA , Attilio BONDANZA , Boris ENGELS , Hyungwook LIM , Akash SOHONI , Louise TREANOR , Xu ZHU , Carla GUIMARAES , Shyamali JAYASHANKAR , Sandeep Tharian KOSHY , Regis CEBE , Michael BARDROFF , Sandra MILLER
摘要: The invention provides methods of making immune effector cells (for example, T cells, NK cells) that express a chimeric antigen receptor (CAR), and compositions generated by such methods.